Abstract: A stent (18) for treating a treatment site (14) of an internal vessel (12) of a mammal, includes a tubular stent frame (222) that is moveable between a retracted configuration (218B) in which the stent frame (222) can be moved within the vessel (12), and an expanded configuration (18A) in which the stent frame (222) is moved against the vessel (12). The stent frame (222) includes a first edge (222A), a second edge (222B), and a longitudinal axis (222C). In certain embodiments, the first edge (222A) is at a first edge angle (224A) relative to the longitudinal axis (222C) when the stent frame (222) is in the expanded configuration (18A) that is less than ninety degrees. As a result thereof, for example, the stent (18) is better suit to fully support a treatment site (14) that is located at an intersection of an angled side branch (12B) and a main branch (12A) of the vessel (12).

Abstract: A treatment device (16C) for treating a treatment site (14) of a vessel (12) includes a tubular shaft (430), a first passageway (434), and a second passageway (436). The shaft (430) includes a distal shaft region (430A) that is sized and shaped to fit within the vessel (12) and a proximal shaft region (430B) that is used to move the distal shaft region (430A) in the vessel (12). The first passageway (434) receives a first guide wire (16A) and extends along at least a portion of the shaft (430). The first passageway (434) includes a first passageway inlet (434A) that receives the first guide wire (16A) and a first passageway outlet (434B). The first passageway inlet (434A) is positioned between the distal shaft region (430A) and the proximal shaft region (430B). The first passageway outlet (434B) is positioned near the proximal region (430B). The second passageway (436) receives a second guide wire (16B) and extends along the shaft (430).

Abstract: A guide catheter (16) for movement within a vessel (12) includes a tubular catheter assembly (20) having an exposed end (16B) that is positioned outside the vessel (12), and a catheter tip (16A) that is movable within the vessel (12) with manipulation of the exposed end (16B). In certain embodiments, at least one of a stiffness and a shape of the catheter tip (16A) can be adjusted between a first configuration (18) and a second configuration (318) with the exposed end (16B). As a result of this design, the physician can move the distal catheter tip (16A) with less resistance through narrow, tortuous vessels (12), the physician can accurately position the distal catheter tip (16A) in the ostium (12C), and the distal catheter tip (16A) is more likely to remain in position in the ostium (12C) when a guide wire and other treatment devices are directed through the guide catheter (16).