Abstract: An anchor assembly, for securing a first portion and a second portion of a separated sternum, can include a lock, an anchor, and a cerclage. The anchor can include a body locatable between the first portion and the second portion of the sternum, where the body can define an end portion. The anchor can include a collar connected to the body and extending outward from the end portion of the body. The collar can engage an outer surface of the sternum to limit movement of the body beyond the outer surface of the sternum. The cerclage can be connected to and can extend from the anchor. The cerclage can be configured to at least partially surround the first portion and the second portion of the separated sternum.

Abstract: A method of replacing a portion of a cranium with a hard tissue implant can include resecting a first portion of the cranium to define a first margin region. The first portion of the cranium can be analyzed to determine if the first margin region is free of cancerous cells. A second portion of the cranium can be resected to define a second margin region that is larger than the first margin region when the first margin region is not free of cancerous cells. An outer implant can be secured to the cranium at the second margin region. An inner implant can be secured to the outer implant.