Abstract: The invention provides aptamer-gene modulator conjugates, where the aptamer and the gene modulator are linked together. The invention further provides a method for cell-specific delivery of gene modulators to hard to transfect cells such as CD4+ cell.

Abstract: Described herein are methods and compositions relating to the treatment of cancer, e.g., breast cancer, using, e.g., aptamer-siRNA chimera molecules.

Abstract: An embodiment of a method of communicating between a surface processing unit and an energy industry tool includes: receiving a power signal from a power source at an integrated interface device of a communication and processing system, the communication and processing system located between a surface processing unit and an energy industry tool, the interface device including a processor and a variable output power supply; receiving a communication at the processor from a surface processing unit; transmitting a control signal from the processor to the variable output power supply, the control signal including a series of pulses having a duty cycle that is varied to cause the power supply to generate a modulated direct current (DC) output signal having at least one of a frequency and an amplitude that is modulated according to a communication protocol to represent the communication; and transmitting the modulated output signal to a tool.

Abstract: The invention provides aptamer-gene modulator conjugates, where the aptamer and the gene modulator are linked together. The invention further provides a method for cell-specific delivery of gene modulators to hard to transfect cells such as CD4+ cell.

Abstract: Described herein are methods and compositions relating to the treatment of cancer, e.g., breast cancer, using, e.g., aptamer-siRNA chimera molecules.

Abstract: Described herein are methods and compositions relating to the treatment of cancer, e.g., breast cancer, using, e.g., aptamer-siRNA chimera molecules.

Abstract: The invention provides aptamer-gene modulator conjugates, where the aptamer and the gene modulator are linked together. The invention further provides a method for cell-specific delivery of gene modulators to hard to transfect cells such as CD4+ cell.

Abstract: Described herein are methods and compositions relating to the treatment of cancer, e.g., breast cancer, using, e.g., aptamer-siRNA chimera molecules.

Abstract: An embodiment of a method of communicating between a surface processing unit and an energy industry tool includes: receiving a power signal from a power source at an integrated interface device of a communication and processing system, the communication and processing system located between a surface processing unit and an energy industry tool, the interface device including a processor and a variable output power supply; receiving a communication at the processor from a surface processing unit; transmitting a control signal from the processor to the variable output power supply, the control signal including a series of pulses having a duty cycle that is varied to cause the power supply to generate a modulated direct current (DC) output signal having at least one of a frequency and an amplitude that is modulated according to a communication protocol to represent the communication; and transmitting the modulated output signal to a tool.

Abstract: The invention provides aptamer-gene modulator conjugates, where the aptamer and the gene modulator are linked together. The invention further provides a method for cell-specific delivery of gene modulators to hard to transfect cells such as CD4+ cell.