Patents by Inventor Adam Wilkinson

Adam Wilkinson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240000861
    Abstract: The disclosure relates to therapeutic compositions comprising isolated bacteria useful in the treatment of ulcerative colitis or Crohn's disease. Related methods and uses are also disclosed.
    Type: Application
    Filed: October 4, 2021
    Publication date: January 4, 2024
    Inventors: Ghaith Bakdash, Simon Harris, Dominika Klisko, Trevor Lawley, Seánín McCluskey, Thomas Mitchell, Anne Neville, Amy Popple, Oliver Rimington, Matthew Robinson, Michael Romanos, Adam Wilkinson
  • Publication number: 20230416694
    Abstract: A modified bacteriophage capable of infecting a plurality of different target bacteria, which bacteriophage includes a toxin gene encoding a toxin protein which is toxic to the target bacteria; wherein the bacteriophage is lytic; and wherein the bacteriophage expresses host range determinant proteins which have a plurality of bacterial host specificities.
    Type: Application
    Filed: May 10, 2023
    Publication date: December 28, 2023
    Inventors: Heather FAIRHEAD, Adam WILKINSON
  • Publication number: 20230265395
    Abstract: Modified bacteriophage, uses thereof, and compositions containing the modified bacteriophage are described. The compositions are useful for human treatment and may treat various conditions, including bacterial infections.
    Type: Application
    Filed: September 19, 2022
    Publication date: August 24, 2023
    Inventors: Heather FAIRHEAD, Adam WILKINSON, Katy PITTS, Anne BARNARD, Emmanuele SEVERI, Neil ANDERSON
  • Patent number: 11732243
    Abstract: A modified bacteriophage capable of infecting a plurality of different target bacteria, which bacteriophage includes a toxin gene encoding a toxin protein which is toxic to the target bacteria; wherein the bacteriophage is lytic; and wherein the bacteriophage expresses host range determinant proteins which have a plurality of bacterial host specificities.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: August 22, 2023
    Assignee: PHICO THERAPEUTICS LTD
    Inventors: Heather Fairhead, Adam Wilkinson
  • Patent number: 11559560
    Abstract: Provided is a modified bacteriophage capable of infecting a target bacterium, which bacteriophage includes an ?/? small acid-soluble spore protein (SASP) gene encoding a SASP which is toxic to the target bacterium, wherein the SASP gene is under the control of a constitutive promoter which is foreign to the bacteriophage and the SASP gene.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: January 24, 2023
    Assignee: PHICO THERAPEUTICS LTD.
    Inventors: Heather Fairhead, Adam Wilkinson, Sarah Holme, Katy Pitts, Alison Jackson
  • Patent number: 11492601
    Abstract: Modified bacteriophage, uses thereof, and compositions containing the modified bacteriophage are described. The compositions are useful for human treatment and may treat various conditions, including bacterial infections.
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: November 8, 2022
    Assignee: PHICO THERAPEUTICS LTD.
    Inventors: Heather Fairhead, Adam Wilkinson, Katy Pitts, Anne Barnard, Emmanuele Severi, Neil Anderson
  • Publication number: 20220347232
    Abstract: The invention relates to bacterial compositions for the treatment or prevention thereof of a disease, in particular an infectious disease such as C. difficile infection.
    Type: Application
    Filed: August 14, 2020
    Publication date: November 3, 2022
    Inventors: Trevor Lawley, Anne Neville, Samuel Forster, Ian Holyer, Dominika Klisko, Seánin McCluskey, Georgia Kapatai, Nan Worrell, Adam Wilkinson
  • Patent number: 11236306
    Abstract: Modified bacteriophage and compositions containing the modified bacteriophage are described. Exemplary compositions are useful for human treatment and may treat various conditions, including bacterial infections.
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: February 1, 2022
    Assignee: PHICO THERAPEUTICS LTD
    Inventors: Heather Fairhead, Adam Wilkinson, Emmanuele Severi, Neil Anderson, Katy Pitts, Anne Barnard
  • Patent number: 10953052
    Abstract: A method for modifying the genome of a lytic target phage, uses of the method and products thereof are described. Compositions comprising such phage are also described. The compositions may be formulated as a medicament, which are useful for human treatment and may treat various conditions, including bacterial infections.
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: March 23, 2021
    Assignee: PHICO THERAPEUTICS LTD
    Inventors: Heather Fairhead, Adam Wilkinson, Anne Barnard, Emmanuele Severi, Neil Anderson, Katy Pitts
  • Publication number: 20210032806
    Abstract: A method of treating a fabric including contacting the fabric with an aqueous liquor comprising a bispyridinium alkane antimicrobial active wherein the aqueous liquor is substantially free of anionic surfactant.
    Type: Application
    Filed: July 8, 2020
    Publication date: February 4, 2021
    Inventors: Craig Adam WILKINSON, Eva Maria PEREZ-PRAT VINUESA
  • Patent number: 10781441
    Abstract: A method for producing one or more hybrid bacteriophage host range determinant (HRD) sequences, which comprises: (1) identifying at least two DNA sequences, each encoding an HRD in a series of regions in the DNA sequence, wherein the HRDs are different from one another, (2) incorporating each region into a vector in which each region is flanked by a recognition site of a restriction enzyme capable of cutting DNA at a specific cleavage site outside of the recognition sequence, so that the cleavage site of the restriction enzyme is situated at the boundary of each region, wherein the cleavage site sequences of the regions from an individual series are different from one another and wherein the cleavage site sequences at the boundaries of corresponding regions from different series are the same; (3) treating the vectors with a restriction enzyme capable of cutting DNA at a specific cleavage site outside of the recognition sequence so as to generate a mixture of the regions; and (4) treating the mixture of the re
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: September 22, 2020
    Assignee: Phico Therapeutics Ltd
    Inventors: Heather Fairhead, Adam Wilkinson, Emmanuele Severi
  • Patent number: 10662398
    Abstract: Low-pH automatic dishwashing detergent composition having a pH as measured in 1% weight aqueous solution at 25° C. of from about 5 to about 7.5 and comprising a protease selected from the group consisting of: (i) a metalloprotease; (ii) a cysteine protease, (iii) an aspartate protease, and mixtures thereof.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: May 26, 2020
    Assignee: The Procter & Gamble Company
    Inventors: Alan Thomas Brooker, Philip Frank Souter, Colin Ure, Craig Adam Wilkinson, Lindsay Suzanne Bewick
  • Publication number: 20190119651
    Abstract: A modified bacteriophage capable of infecting a plurality of different target bacteria, which bacteriophage includes a toxin gene encoding a toxin protein which is toxic to the target bacteria; wherein the bacteriophage is lytic; and wherein the bacteriophage expresses host range determinant proteins which have a plurality of bacterial host specificities.
    Type: Application
    Filed: April 7, 2017
    Publication date: April 25, 2019
    Applicant: Phico Therapeutics Ltd
    Inventors: Heather FAIRHEAD, Adam WILKINSON
  • Patent number: 10266796
    Abstract: Low-pH automatic dishwashing detergent composition comprising a low temperature amylase and a lime soap dispersing agent and wherein the composition has a pH as measured in 1% weight aqueous solution at 25° C. of from about 5 to about 7.5, preferably less than 6.9.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: April 23, 2019
    Assignee: The Procter & Gamble Company
    Inventors: Philip Frank Souter, Alan Thomas Brooker, Colin Ure, Craig Adam Wilkinson, Lindsay Suzanne Bewick, Kelly Ann Millward
  • Publication number: 20190093100
    Abstract: A method for producing one or more hybrid bacteriophage host range determinant (HRD) sequences, which comprises: (1) identifying at least two DNA sequences, each encoding an HRD in a series of regions in the DNA sequence, wherein the HRDs are different from one another, (2) incorporating each region into a vector in which each region is flanked by a recognition site of a restriction enzyme capable of cutting DNA at a specific cleavage site outside of the recognition sequence, so that the cleavage site of the restriction enzyme is situated at the boundary of each region, wherein the cleavage site sequences of the regions from an individual series are different from one another and wherein the cleavage site sequences at the boundaries of corresponding regions from different series are the same; (3) treating the vectors with a restriction enzyme capable of cutting DNA at a specific cleavage site outside of the recognition sequence so as to generate a mixture of the regions; and (4) treating the mixture of the re
    Type: Application
    Filed: April 7, 2017
    Publication date: March 28, 2019
    Inventors: Heather FAIRHEAD, Adam WILKINSON, Emmanuele SEVERI
  • Publication number: 20190071648
    Abstract: Provided is a modified bacteriophage capable of infecting a target bacterium, which bacteriophage includes an ?/? small acid-soluble spore protein (SASP) gene encoding a SASP which is toxic to the target bacterium, wherein the SASP gene is under the control of a constitutive promoter which is foreign to the bacteriophage and the SASP gene.
    Type: Application
    Filed: September 12, 2018
    Publication date: March 7, 2019
    Inventors: Heather FAIRHEAD, Adam Wilkinson, Sarah Holme, Kathy Pitts, Alison Jackson
  • Patent number: 10106784
    Abstract: Provided is a modified bacteriophage capable of infecting a target bacterium, which bacteriophage includes an ?/? small acid-soluble spore protein (SASP) gene encoding a SASP which is toxic to the target bacterium, wherein the SASP gene is under the control of a constitutive promoter which is foreign to the bacteriophage and the SASP gene.
    Type: Grant
    Filed: May 5, 2016
    Date of Patent: October 23, 2018
    Assignee: PHICO THERAPEUTICS
    Inventors: Heather Fairhead, Adam Wilkinson, Sarah Holme, Katy Pitts, Alison Jackson
  • Patent number: 10081782
    Abstract: Low-pH automatic dishwashing detergent composition comprising an endoprotease having an isoelectric point from about 4 to about 9 and wherein the composition has a pH as measured in 1% weight aqueous solution at 25° C. of from about 5 to about 7.5.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: September 25, 2018
    Assignee: The Procter & Gamble Company
    Inventors: Alan Thomas Brooker, Philip Frank Souter, Colin Ure, Craig Adam Wilkinson, Lindsay Suzanne Bewick
  • Publication number: 20180094224
    Abstract: The present invention relates to a solid free flowing particulate laundry detergent composition comprising: (a) anionic detersive surfactant; (b) wherein the composition is essentially free of zeolite builder; (c) wherein the composition is essentially free of phosphate builder; (d) wherein the composition is essentially free of sodium carbonate; (e) wherein the composition is essentially free of sodium silicate; (f) from about 4 wt % to about 20 wt % organic acid; and (g) hueing agent selected from Acid Violet 50, Direct Violet 9, 66 and 99, Solvent Violet 13 and any combination thereof, wherein the composition at 1 wt % dilution in deionized water at 20° C., has an equilibrium pH in the range of from about 6.5 to about 9.
    Type: Application
    Filed: October 3, 2017
    Publication date: April 5, 2018
    Inventors: Andre CHIEFFI, Alan Thomas BROOKER, Craig Adam WILKINSON, Linsey Sarah FULLER, Paul Anthony GOULD, Hossam Hassan TANTAWY
  • Patent number: D1050789
    Type: Grant
    Filed: August 1, 2022
    Date of Patent: November 12, 2024
    Assignee: COSTA EXPRESS LIMITED
    Inventors: Adam Wilkinson, Mark Jones, Nathan Matthews, Christoph Proessler