Patents by Inventor Adam Y. LIN

Adam Y. LIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HYDROPHOBIC DRUGS IN ORGANIC CORE HIGH DENSITY LIPOPROTEIN (HDL) NANOPARTICLES
    Publication number: 20230414509
    Abstract: Disclosed herein are high-density lipoprotein-like nanoparticles (HDL-NP) having a soft material core (e.g., a lipid-conjugated inorganic core) associated with hydrophobic therapeutic agents. In some embodiments, the HDL-NPs are targeted to scavenger receptor type B1 (SR-B1). In some embodiments, the hydrophobic therapeutic agents are chemotherapeutic agents. Also disclosed herein are methods for treating disorders such as cancer with the HDL-NPs.
    Type: Application
    Filed: October 22, 2021
    Publication date: December 28, 2023
    Inventors: Stephen E. Henrich, Jonathan S. Rink, Adam Y. Lin, C. Shad Thaxton, Leo I. Gordon, Sonbinh T. Nguyen, Steven T. Rosen, David Horne, Xu Hannah Zhang
  • GOLD NANOPARTICLES/NANOSHELLS IMMUNE CONJUGATES FOR ENHANCED IMMUNOTHERAPY AND PHOTOTHERMAL THERAPY FOR HEMATOLOGIC MALIGNANCIES
    Publication number: 20220401576
    Abstract: Disclosed herein are CpG conjugated nanoparticles for immunotherapy and photothermal therapy. The composition comprises class B CpG conjugated nanoparticles and/or a class C CpG conjugated nanoparticles where the class B CpG conjugated nanoparticles comprises a nanoparticle core and a class B CpG conjugated thereto and the class C CpG conjugated nanoparticles comprises a nanoparticle core and a class C CpG conjugated thereto.
    Type: Application
    Filed: November 2, 2020
    Publication date: December 22, 2022
    Inventors: Adam Y. Lin, Leo I. Gordon
  • Universal microbial diagnostics using random DNA probes
    Patent number: 11104964
    Abstract: The present disclosure is directed to compositions and methods present a universal microbial diagnostic (UMD) platform to screen for microbial organisms in a sample using a small number of random DNA probes that are agnostic to the target DNA sequences. The UMD platform can be used to direct and monitor appropriate treatments, thus minimizing the risk of antibiotic resistance, and enhancing patient care.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: August 31, 2021
    Assignee: William Marsh Rice University
    Inventors: Rebekah A. Drezek, Richard G. Baraniuk, Amirali Aghazadeh, Mona Sheikh, Adam Y. Lin, Allen L. Chen, Pallavi Bugga
  • UNIVERSAL MICROBIAL DIAGNOSTICS USING RANDOM DNA PROBES
    Publication number: 20180355411
    Abstract: The present disclosure is directed to compositions and methods present a universal microbial diagnostic (UMD) platform to screen for microbial organisms in a sample using a small number of random DNA probes that are agnostic to the target DNA sequences. The UMD platform can be used to direct and monitor appropriate treatments, thus minimizing the risk of antibiotic resistance, and enhancing patient care.
    Type: Application
    Filed: April 3, 2018
    Publication date: December 13, 2018
    Applicant: WILLIAM MARSH RICE UNIVERSITY
    Inventors: Rebekah A. DREZEK, Richard G. BARANIUK, Amirali AGHAZADEH, Mona SHEIKH, Adam Y. LIN, Allen L. CHEN, Pallavi BUGGA