Patents by Inventor Adeela Kamal

Adeela Kamal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-CXCR4 ANTIBODIES AND METHODS OF USE
    Publication number: 20140314784
    Abstract: The disclosure relates to antibodies or antigen binding fragments that specifically bind to CXCR4 and inhibit the biological activity of CXCR4 and uses of such agents. More specifically the disclosure relates to fully human antibodies or antigen binding fragments directed to CXCR4 that specifically bind to CXCR4 and uses of these antibodies. Aspects of the disclosure also relate to hybridomas or other cell lines expressing such antibodies. The disclosed antibodies (including antigen binding fragments) are useful as diagnostics and for the treatment of diseases associated with the activity and/or expression of CXCR4.
    Type: Application
    Filed: July 19, 2012
    Publication date: October 23, 2014
    Applicant: Medlmmune Limited
    Inventors: Vahe Bedian, Youzhen Wang, Ian Foltz, Palaniswami Rathanaswami, Jaspal Singh Kang, Adeela Kamal, Philipp Steiner
  • Assays and Implements for Determining and Modulating HSP90 Binding Activity
    Publication number: 20080318338
    Abstract: Ligand binding assays as applied to HSP90s as receptors or ligands, and reagents useful therefore, are described and claimed, as are methods of assaying for HSP90 modulators and methods of using the resulting products identified thereby.
    Type: Application
    Filed: April 15, 2008
    Publication date: December 25, 2008
    Inventors: Adeela Kamal, Francis J. Burrows, Lin Zhang, Marcus F. Boehm
  • Methods and Compositions for Treating Chronic Lymphocytic Leukemia
    Publication number: 20080280878
    Abstract: Novel method of treating chronic lymphocytic leukemia by the administering of HSP90 inhibitors, particularly ansamycins, more particularly I 7-allylamino-I 7-demethoxygetdanarnycin (17-AAG).
    Type: Application
    Filed: November 2, 2005
    Publication date: November 13, 2008
    Inventors: Januario E. Castro, Thomas J. Kipps, Francis J. Burrows, Adeela Kamal, Carlos E. Prada
  • Cytotoxins and diagnostic imaging agents comprising hsp90 ligands
    Publication number: 20060251574
    Abstract: Cytotoxic compounds and diagnostic imaging agents comprising HSP90-ligands and methods of use thereof are described.
    Type: Application
    Filed: June 12, 2003
    Publication date: November 9, 2006
    Inventors: Adeela Kamal, Francis Burrows, Lin Zhang, Marcus Boehm
  • Assays and implements for determining and modulating hsp90 binding activity
    Publication number: 20050074457
    Abstract: Ligand binding assays as applied to HSP90s as receptors or ligands, and reagents useful therefore, are described and claimed, as are methods of assaying for HSP90 modulators and methods of using the resulting products identified thereby.
    Type: Application
    Filed: December 12, 2002
    Publication date: April 7, 2005
    Inventors: Adeela Kamal, Francis Burrows, Lin Zhang, Marcus Boehm
  • Assays for inhibitors of neuronal transport of Alzheimer's amyloid precursor protein
    Patent number: 6673332
    Abstract: The present invention provides methods and compositions for the treatment of Alzheimer's disease. In particular, the present invention provides methods and compositions suitable to assess, characterize, and identify inhibitors of neuronal transport of Alzheimer's amyloid precursor protein.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: January 6, 2004
    Assignee: The Regents of the University of California
    Inventors: Lawrence S. B. Goldstein, Adeela Kamal, Gorazd Stokin