Abstract: A method of imaging an organism includes introducing a composite nanoparticle into a circulating fluid of an organism to form a circulating fluid mixture in the organism is provided. The composite nanoparticle comprises a core comprising at least one of a contrast agent and a magnetic material, and at least one layer of biocompatible material surrounding the core. The method further includes receiving an image of at least a portion of the organism where the circulating fluid has circulated, removing at least a portion of the circulating fluid mixture from the organism at a first rate, applying a magnetic field to the removed portion of the circulating fluid mixture to selectively remove the composite nanoparticle from the circulating fluid mixture and to produce a filtered fluid mixture, and returning the filtered fluid mixture to the circulating fluid of the organism at a second rate.

Abstract: High resolution time sequences of 3D images that show the dynamics of a time varying changes are provided. The 3D time series of images representing an object that include time varying changes may be produced from lower dimensional image time sequences, such as 2D images. The 2D images may be generated using angiography and may include fluid flow information (e.g., arrival times). The fluid flow information may be provided, for example, by injecting a chemical into the fluid and analyzing its position in the object or body over time. A varying contrast model may be applied to determine the location of the chemical at different points in time which may assist in detecting an ailment.

Abstract: High resolution time sequences of 3D images that show the dynamics of a time varying changes are provided. The 3D time series of images representing an object that include time varying changes may be produced from lower dimensional image time sequences, such as 2D images. The 2D images may be generated using angiography and may include fluid flow information (e.g., arrival times). The fluid flow information may be provided, for example, by injecting a chemical into the fluid and analyzing its position in the object or body over time. A varying contrast model may be applied to determine the location of the chemical at different points in time which may assist in detecting an ailment.