Patents by Inventor Adela Bonoiu

Adela Bonoiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of using gold nanorods-siRNA complexes
    Patent number: 8035016
    Abstract: Provided are methods and compositions for inhibiting expression of one or more target genes. The compositions contain RNA polynucleotides that can inhibit expression of a target gene via RNA interference (RNAi) electrostatically complexed with surface functionalized gold nanorods (GNRs). The RNA polynucleotides are not covalently bound to the surface functionalized GNRs. The method involves inhibiting expression of a target gene in an individual. The method is performed by administering to the individual an effective amount of a composition containing surface functionalized GNRs electrostatically complexed with RNA polynucleotides, such as siRNA, that can inhibit expression of the target gene via RNAi. The siRNA is not covalently bound to the surface functionalized GNRs.
    Type: Grant
    Filed: September 8, 2009
    Date of Patent: October 11, 2011
    Assignee: The Research Foundation of State University of New York
    Inventors: Earl J. Bergey, Adela Bonoiu, Supriya Mahajan, Paras N. Prasad, Indrajit Roy, Stanley A. Schwartz, Ken-Tye Yong
  • GOLD NANOROD-siRNA COMPLEXES AND METHODS OF USING SAME
    Publication number: 20100125100
    Abstract: Provided are methods and compositions for inhibiting expression of one or more target genes. The compositions contain RNA polynucleotides that can inhibit expression of a target gene via RNA interference (RNAi) electrostatically complexed with surface functionalized gold nanorods (GNRs). The RNA polynucleotides are not covalently bound to the surface functionalized GNRs. The method involves inhibiting expression of a target gene in an individual. The method is performed by administering to the individual an effective amount of a composition containing surface functionalized GNRs electrostatically complexed with RNA polynucleotides, such as siRNA, that can inhibit expression of the target gene via RNAi. The siRNA is not covalently bound to the surface functionalized GNRs.
    Type: Application
    Filed: September 8, 2009
    Publication date: May 20, 2010
    Inventors: Earl J. Bergey, Adela Bonoiu, Supriya Mahajan, Paras N. Prasad, Indrajit Roy, Stanley A. Schwartz, Ken-Tye Yong