Patents by Inventor Adele Kay Fielding

Adele Kay Fielding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7854928
    Abstract: A method for treating cancer cells is provided comprising directly or systemically administering a therapeutically effective dose of an attenuated measles virus. In one embodiment, the therapeutically effective dose is from about 103 pfus to about 1012 pfus and is delivered by direct injection into a group of cancer cells or via intravenous injection.
    Type: Grant
    Filed: January 15, 2010
    Date of Patent: December 21, 2010
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Stephen J. Russell, Adele Kay Fielding, Kah-Whye Peng, Deanna Grote
  • Patent number: 7846429
    Abstract: Disclosed are compositions comprising a recombinant nucleic acid vector including a nucleotide sequence encoding a syncytium-inducing polypeptide expressible on a eukaryotic cell surface, and a host cell containing the recombinant vector and expressing the syncytium inducing polypeptide on its cell surface, the vectors and resultant host cells expressing the syncytium inducing polypeptide being useful for selective elimination of unwanted cells.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: December 7, 2010
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Stephen James Russell, Frances Joanne Morling, Adele Kay Fielding, Francois-Loic Cosset, Roberto Cattaneo
  • Patent number: 7670598
    Abstract: A method for treating cancer cells is provided comprising directly or systemically administering a therapeutically effective dose of an attenuated measles virus. In one embodiment, the therapeutically effective dose is from about 103 pfus to about 1012 pfus and is delivered by direct injection into a group of cancer cells or via intravenous injection.
    Type: Grant
    Filed: June 9, 2008
    Date of Patent: March 2, 2010
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Stephen J. Russell, Adele Kay Fielding, Kah-Whye Peng, Deanna Grote
  • Publication number: 20080226610
    Abstract: Disclosed are compositions comprising a recombinant nucleic acid vector including a nucleotide sequence encoding a syncytium-inducing polypeptide expressible on a eukaryotic cell surface, and a host cell containing the recombinant vector and expressing the syncytium inducing polypeptide on its cell surface, the vectors and resultant host cells expressing the syncytium inducing polypeptide being useful for selective elimination of unwanted cells.
    Type: Application
    Filed: October 31, 2007
    Publication date: September 18, 2008
    Inventors: Stephen James Russell, Frances Joanne Morling, Adele Kay Fielding, Francis-Loic Cosset, Roberto Cattaneo
  • Publication number: 20080227740
    Abstract: Disclosed are compositions comprising a recombinant nucleic acid vector including a nucleotide sequence encoding a syncytium-inducing polypeptide expressible on a eukaryotic cell surface, and a host cell containing the recombinant vector and expressing the syncytium inducing polypeptide on its cell surface, the vectors and resultant host cells expressing the syncytium inducing polypeptide being useful for selective elimination of unwanted cells.
    Type: Application
    Filed: October 31, 2007
    Publication date: September 18, 2008
    Inventors: Stephen James Russell, Frances Joanne Morling, Adele Kay Fielding, Francois-Loic Cosset, Roberto Cattaneo
  • Publication number: 20080171027
    Abstract: Disclosed are compositions comprising a recombinant nucleic acid vector including a nucleotide sequence encoding a syncytium-inducing polypeptide expressible on a eukaryotic cell surface, and a host cell containing the recombinant vector and expressing the syncytium inducing polypeptide on its cell surface, the vectors and resultant host cells expressing the syncytium inducing polypeptide being useful for selective elimination of unwanted cells.
    Type: Application
    Filed: October 31, 2007
    Publication date: July 17, 2008
    Inventors: Stephen James Russell, Frances Joanne Morling, Adele Kay Fielding, Francois-Loic Cosset, Roberto Cattaneo
  • Publication number: 20080171026
    Abstract: Disclosed are compositions comprising a recombinant nucleic acid vector including a nucleotide sequence encoding a syncytium-inducing polypeptide expressible on a eukaryotic cell surface, and a host cell containing the recombinant vector and expressing the syncytium inducing polypeptide on its cell surface, the vectors and resultant host cells expressing the syncytium inducing polypeptide being useful for selective elimination of unwanted cells.
    Type: Application
    Filed: October 31, 2007
    Publication date: July 17, 2008
    Inventors: Stephen James Russell, Frances Joanne Morling, Adele Kay Fielding, Francis-Loic Cosset, Roberto Cattaneo
  • Patent number: 7317004
    Abstract: Disclosed are compositions comprising a recombinant nucleic acid vector including a nucleotide sequence encoding a syncytium-inducing polypeptide expressible on a eukaryotic cell surface, and a host cell containing the recombinant vector and expressing the syncytium inducing polypeptide on its cell surface, the vectors and resultant host cells expressing the syncytium inducing polypeptide being useful for selective elimination of unwanted cells.
    Type: Grant
    Filed: August 18, 2005
    Date of Patent: January 8, 2008
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Stephen James Russell, Frances Joanne Morling, Adele Kay Fielding, Francois-Loic Cosset, Roberto Cattaneo
  • Patent number: 7314868
    Abstract: Disclosed are compositions comprising a recombinant nucleic acid vector including a nucleotide sequence encoding a syncytium-inducing polypeptide expressible on a eukaryotic cell surface, and a host cell containing the recombinant vector and expressing the syncytium inducing polypeptide on its cell surface, the vectors and resultant host cells expressing the syncytium inducing polypeptide being useful for selective elimination of unwanted cells.
    Type: Grant
    Filed: December 10, 2003
    Date of Patent: January 1, 2008
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Stephen James Russell, Frances Joanne Morling, Adele Kay Fielding, Francois-Loic Cosset, Roberto Cattaneo
  • Publication number: 20040253214
    Abstract: Disclosed are compositions comprising a recombinant nucleic acid vector including a nucleotide sequence encoding a syncytium-inducing polypeptide expressible on a eukaryotic cell surface, and a host cell containing the recombinant vector and expressing the syncytium inducing polypeptide on its cell surface, the vectors and resultant host cells expressing the syncytium inducing polypeptide being useful for selective elimination of unwanted cells,
    Type: Application
    Filed: December 10, 2003
    Publication date: December 16, 2004
    Applicant: Mayo Foundation For Medical Education and Research, a Minnesota corporation
    Inventors: Stephen James Russell, Frances Joanne Morling, Adele Kay Fielding, Francois-Loic Cosset, Roberto Cattaneo
  • Publication number: 20040161849
    Abstract: Materials and methods for transferring nucleic acid encoding a polypeptide for treating a disease or disorder into populations of quiescent cells such as haematopoietic stem cells (HSCs), using retroviral packaging cell lines and retroviral particles expressing and displaying a growth factor such as stem cell factor (SCF) on the cell surface or as a fusion with a viral envelope protein. The present invention also relates compositions comprising the retroviral packaging cell lines and viral particles, and their use in methods of medical treatment, in vivo and ex vivo.
    Type: Application
    Filed: February 17, 2004
    Publication date: August 19, 2004
    Applicant: Mayo Foundation For Medical Education and Research, a Minnesota corporation
    Inventors: Stephen James Russell, Adele Kay Fielding, Colin Maurice Casimir
  • Patent number: 6750206
    Abstract: Disclosed are compositions comprising a recombinant nucleic acid vector including a nucleotide sequence encoding a syncytium-inducing polypeptide expressible on a eukaryotic cell surface, and a host cell containing the recombinant vector and expressing the syncytium inducing polypeptide on its cell surface, the vectors and resultant host cells expressing the syncytium inducing polypeptide being useful for selective elimination of unwanted cells.
    Type: Grant
    Filed: April 30, 1998
    Date of Patent: June 15, 2004
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Stephen James Russell, Frances Joanne Morling, Adele Kay Fielding, Francois-Loic Cosset, Roberto Cattaneo
  • Patent number: 6723561
    Abstract: Materials and methods for transferring nucleic acid encoding a polypeptide for treating a disease or disorder into populations of quiescent cells such as haematopoietic stem cells (HSCs), using retroviral packaging cell lines and retroviral particles expressing and display a growth factor such as stem cell factor (SCF) on the cell surface or as a fusion with a viral envelope protein. The present invention also relates to compositions comprising the retroviral packaging cell lines and retroviral particles, and their use in methods of medical treatment, in vivo and ex vivo.
    Type: Grant
    Filed: October 5, 1998
    Date of Patent: April 20, 2004
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Stephen James Russell, Adele Kay Fielding, Colin Maurice Casimir