Patents by Inventor Ademar Alves da Silva Filho

Ademar Alves da Silva Filho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Medicinal composition intended for the treatment of erectile dysfunction in mammals and use of the composition
    Patent number: 8829049
    Abstract: The use of cubebin, dibenzylbutyrolactolic lignan, its semi-synthetic and synthetic derivatives for the treatment of erectile dysfunction is shown and disclosed.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: September 9, 2014
    Assignee: ACEF S.A.
    Inventors: Sérgio Albuquerque, Jairo Kenupp Bastos, Paulo Sérgio Calefi, Katia Jorge Ciuffi, Wilson Roberto Cunha, Rosangela da Silva de Laurentiz, Rodrigo Lucarini, Eduardo José Nassar, Ademar Alves da Silva Filho, Márcio Luís Andrade e Silva
  • MEDICINAL COMPOSITION INTENDED FOR THE TREATMENT OF ERECTILE DYSFUNCTION IN MAMMALS AND USE OF THE COMPOSITION
    Publication number: 20130102660
    Abstract: The use of cubebin, dibenzylbutyrolactolic lignan, its semi-synthetic and synthetic derivatives for the treatment of erectile dysfunction is shown and disclosed.
    Type: Application
    Filed: December 21, 2009
    Publication date: April 25, 2013
    Applicant: ACEF S.A.
    Inventors: Sérgio Albuquerque, Jáiro Kenupp Bastos, Paulo Sérgio Calefi, Katia Jorge Ciuffi, Wilson Roberto Cunha, Rosangela da Silva de Laurentiz, Rodrigo Lucarini, Eduardo José Nassar, Ademar Alves da Silva Filho, Márcio Luís Andrae e Silva
  • Process To Obtain Synthetic And Semi-Synthetic Lignan Derivatives, Their Antiparasitic Activities And Corresponding Pharmaceutical Formulations, Including The Therapeutic Method Using Said Lignan For The Treatment Of Parasitosis
    Publication number: 20080194678
    Abstract: A process to obtain synthetic and semi-synthetic derivatives of lignans, especially dibenzylbutyrolactonic, tetrahydrofuranic, aryltetralynic, furofuranic and dibenzocyclooctanic lignans obtained by means of partial synthesis and/or full synthesis or also by isolation from plant extracts. It refers to a process to obtain synthetic and semi-synthetic derivatives of (?)-cubebin, such as: (?)-O-acetylcubebin; (?)-O-methylcubebin; (?)-O—N,N-(dimethylamino-ethyl)-cubebin; (?)-hinokinin; (?)-6,6?-dinitroinokinine; (?)-O-benzylcubebin; (?)-6,6?-diaminoinokinin, (?)-6,6?-dinitroinokinin, as well as to obtain dibenzocyclooctanic lignans from dibenzylbutyrolactoinic lignans by means of structural modifications in the positions 7, 7?, 8, 8?, 9? and in the aromatic rings (introduction and/or substitution of functional groups such as: —OH, —CO2H, —CO2CH3, —NO2, —NH2, —OCH3, —OAc, —SO2CH3, —SO2NH2, prenyl and halogens) is provided. A therapeutic method using the derivatives is also provided.
    Type: Application
    Filed: July 14, 2006
    Publication date: August 14, 2008
    Applicant: Fundacao de Amparo a Pesquissa do Estado de Aao Pa
    Inventors: Marcio Luis Andrade e Silva, Rosangela da Silva, Vanderlei Rodrigues, Olavo dos Santos Pereira, Ademar Alves da Silva Filho, Paulo Marcos Donate, Sergio Albuquerque, Jairo Kenupp Bastos