Patents by Inventor Adhar Manna

Adhar Manna has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for affecting virulence determinants in bacteria
    Patent number: 7339043
    Abstract: A novel sarR gene and sarR gene product which down regulates the expression of sarA and the resulting virulence determinants in Staphylococcus aureus is provided. Methods for modulating the expression of sarA and virulence determinants are also provided. A preferred embodiment of the present invention provides structural information relating to the gene product and enables the identification and formulation of lead compounds and reducements for treating and preventing infections by S. aureus and related bacteria.
    Type: Grant
    Filed: February 22, 2005
    Date of Patent: March 4, 2008
    Assignee: Trustees of Dartmouth College
    Inventors: Ambrose L. Cheung, Adhar Manna
  • Compositions and methods for affecting virulence determinants in bacteria
    Patent number: 7258995
    Abstract: A novel sarR gene and sarR gene product which down regulates the expression of sarA and the resulting virulence determinants in Staphylococcus aureus is provided. Methods for modulating the expression of sarA and virulence determinants are also provided. A preferred embodiment of the present invention provides structural information relating to the gene product and enables the identification and formulation of lead compounds and reducements for treating and preventing infections by S. aureus and related bacteria.
    Type: Grant
    Filed: January 11, 2002
    Date of Patent: August 21, 2007
    Assignee: Trustees of Dartmouth College
    Inventors: Ambrose L. Cheung, Adhar Manna, Gongyi Zhang
  • Compositions and methods for affecting virulence determinants in bacteria
    Publication number: 20050239704
    Abstract: A novel sarR gene and sarR gene product which down regulates the expression of sarA and the resulting virulence determinants in Staphylococcus aureus is provided. Methods for modulating the expression of sarA and virulence determinants are also provided. A preferred embodiment of the present invention provides structural information relating to the gene product and enables the identification and formulation of lead compounds and reducements for treating and preventing infections by S. aureus and related bacteria.
    Type: Application
    Filed: February 22, 2005
    Publication date: October 27, 2005
    Inventors: Ambrose Cheung, Adhar Manna, Gongyi Zhang
  • Compositions and methods for affecting virulence determinants in bacteria
    Publication number: 20030114650
    Abstract: A novel sarR gene and sarR gene product which down regulates the expression of sarA and the resulting virulence determinants in Staphylococcus aureus is provided. Methods for modulating the expression of sarA and virulence determinants are also provided. A preferred embodiment of the present invention provides structural information relating to the gene product and enables the identification and formulation of lead compounds and reducements for treating and preventing infections by S. aureus and related bacteria.
    Type: Application
    Filed: January 11, 2002
    Publication date: June 19, 2003
    Inventors: Ambrose L. Cheung, Adhar Manna, Gongyi Zhang