Abstract: A system and method for generating a gas-supersaturated fluid and delivering the fluid at high delivery pressures to thereby prevent bubble nucleation is disclosed. The system comprises a housing for containing a removable fluid assembly for housing a fluid to be gas-supersaturated and a drive assembly for delivering the fluid to a delivery site. The housing assembly comprises a cylinder and a piston which may be advanced along the inner surface of the cylinder to pressurize and to deliver the fluid. To generate a gas-supersaturated fluid, the housing assembly is removed from the system housing, filled with a fluid, and gas is introduced at or slightly above the desired gas partial pressure into the cylinder.

Abstract: A fluid level detector system, which may measure the amount of fluid in a reservoir, and may further trigger an alarm when the fluid level in the cassette reaches a low level condition. The cassette's reservoir may contain a transient sterile solution, which is moving through the cassette to be either cooled or heated in the heat exchanger area. The detection scheme includes a ring magnet housed in a float assembly located in the fluid reservoir of the cassette and, e.g., two magnetic sensors, such as may form a Hall effect integrated circuit, which may be fixed within the console.

Abstract: A system and method for generating a gas-supersaturated fluid and delivering the fluid at high delivery pressures to thereby prevent bubble nucleation is disclosed. The system comprises a housing for containing a removable fluid assembly for housing a fluid to be gas-supersaturated and a drive assembly for delivering the fluid to a delivery site. The housing assembly comprises a cylinder and a piston which may be advanced along the inner surface of the cylinder to pressurize and to deliver the fluid. To generate a gas-supersaturated fluid, the housing assembly is removed from the system housing, filled with a fluid, and gas is introduced at or slightly above the desired gas partial pressure into the cylinder.