Patents by Inventor Aditi QAMRA

Aditi QAMRA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220081723
    Abstract: The present invention relates to a method of identifying a patient suffering from cancer as benefiting or not benefiting from immune checkpoint inhibition therapy comprising the steps of measuring an expression level of one or more preselected markers in a cancerous biological sample obtained from the patient, identifying a differentially expressed alternative promoter based on the expression level of the one or more preselected markers, calculating an alternative promoter usage score and identifying the patient as benefiting or not benefiting from immune checkpoint inhibition therapy using the alternative promoter usage score. The present invention also relates to a biomarker for excluding a patient suffering from cancer from immune checkpoint inhibition therapy.
    Type: Application
    Filed: December 20, 2019
    Publication date: March 17, 2022
    Inventors: Patrick Tan, Raghav Sundar, Kie Kyon Huang, Aditi Qamra, Jonathan Goke, Deniz Demircioglu
  • Publication number: 20210301348
    Abstract: The present invention relates to a method for determining the presence or absence of at least one promoter in a cancerous biological sample relative to a non-cancerous biological sample. The present invention also relates to a method for determining the prognosis of cancer in a subject, a method for modulating the activity of at least one cancer-associated promoter in a cell, a method for modulating the immune response of a subject to cancer, a method for determining the presence of at least one cancer-associated promoter in a cancerous biological sample relative to a non-cancerous biological sample and a biomarker for detecting cancer in a subject.
    Type: Application
    Filed: February 16, 2017
    Publication date: September 30, 2021
    Inventors: Patrick TAN, Aditi QAMRA, Manjie XING, Wen Fong OOI
  • Publication number: 20160355886
    Abstract: The present invention is directed to methods for determining the activity of a promoter. The present invention further describes a method for determining the susceptibility of a subject to cancer and biomarkers for detecting cancer in a subject.
    Type: Application
    Filed: December 30, 2014
    Publication date: December 8, 2016
    Inventors: Boon Ooi Patrick TAN, Masafumi MURATANI, Aditi QAMRA