Patents by Inventor Aditya Konar
Aditya Konar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9408888Abstract: The present invention describes a novel bivalent helically constrained peptide targeted against S100B that is an effective anti-cancer drug against cancers that over-express S100B. This helix mimetic targeted against S100B induces rapid apoptosis in cancer cells that over-express a calcium binding protein S100B through simultaneous inhibition of key growth pathways including activation of p53.Type: GrantFiled: January 30, 2012Date of Patent: August 9, 2016Assignee: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Amlanjyoti Dhar, Shampa Mallick, Israr Ahmed, Aditya Konar, Santu Bandyopadhyay, Siddhartha Roy
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Patent number: 9302967Abstract: The present invention relates to compounds of general formula 1 for the treatment of bronchial asthma by inhibition of IL-4 or IL-5 pathway inhibition. The present invention also relates to the use of compound of general formula 1 for the treatment of bronchial by inhibition of IL-4 or IL-5 pathway. The present invention also relates to the method of treating asthma by inhibition of IL-4 or IL-5 pathway by administration of compound or said composition through oral, intranasal, route or by inhalation to a mammal in need thereof. Compound of general formula 1 may be used for reducing perivascular and peribronchial inflammation.Type: GrantFiled: April 11, 2012Date of Patent: April 5, 2016Assignee: Council of Scientific & Industrial ResearchInventors: Santu Bandyopadhyay, Balaram Ghosh, Parasuraman Jaisankar, Bikas Chandra Pal, Siddhartha Roy, Bholanath Paul, Arjun Ram, Ulaganathan Mabalirajan, Nahid Ali, Arun Bandopadhyay, Aditya Konar, Jayashree Bagchi Chakraborty, Indrani Choudhury Mukherjee, Jaydeep Chaudhuri, Sanjit Kumar Mahato, Anirban Manna, Roma Sinha, Pradyot Bhattacharya, Jayaraman Vinayagam, Deba Prasad Jana, Sushovan Chowdhury
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Patent number: 9290473Abstract: The present invention relates to compounds of general formula 1 for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention also relates to the use of compound of general formula 1 for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention further relates to a method of treating malignancy by inhibition of PI3-Akt pathway and or induction of NO by administration of compound or said composition to a mammal in need thereof.Type: GrantFiled: January 12, 2010Date of Patent: March 22, 2016Assignee: COUCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Santu Bandyopadhyay, Bikas Chandra Pal, Jaisankar Parasuraman, Siddhartha Roy, Jayashree Bagchi Chakrabotry, Indrani Choudhury Mukherjee, Sanjit Kumar Mahato, Aditya Konar, Srabanti Rakshit, Labanya Mandal, Dipyaman Ganguly, Kausik Paul, Anirban Manna, Jayaraman Vinayagam, Churala Pal
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Publication number: 20140155331Abstract: The present invention describes a novel bivalent helically constrained peptide targeted against S100B that is an effective anti-cancer drug against cancers that over-express S100B. This helix mimetic targeted against S100B induces rapid apoptosis in cancer cells that over-express a calcium binding protein S100B through simultaneous inhibition of key growth pathways including activation of p53.Type: ApplicationFiled: January 30, 2012Publication date: June 5, 2014Inventors: Amlanjyoti Dhar, Shampa Mallick, Israr Ahmed, Aditya Konar, Santu Bandyopadhyay, Siddhartha Roy
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Publication number: 20140135393Abstract: The present invention relates to compounds of general formula 1 for the treatment of bronchial asthma by inhibition of IL-4 or IL-5 pathway inhibition. The present invention also relates to the use of compound of general formula 1 for the treatment of bronchial by inhibition of IL-4 or IL-5 pathway. The present invention also relates to the method of treating asthma by inhibition of IL-4 or IL-5 pathway by administration of compound or said composition through oral, intranasal, route or by inhalation to a mammal in need thereof. Compound of general formula 1 may be used for reducing perivascular and peribronchial inflammation.Type: ApplicationFiled: April 11, 2012Publication date: May 15, 2014Applicant: Council of Scientific & Industrial ResearchInventors: Santu Bandyopadhyay, Balaram Ghosh, Parasuraman Jaisankar, Bikas Chandra Pal, Siddhartha Roy, Balaram Ghosh, Parasuraman Jaisankar, Bikas Pal, Nahid Ali, Siddhartha Roy, Bholanath Paul, Arjun Ram, Siddhartha Roy, Bholanath Paul, Arjun Ram, Ulaganathan Mabalirajan, Nahid Ali, Arun Bandopadhyay, Aditya Konar, Jayashree Bagchi Chakraborty, Indrani Chowdhury Mukherjee, Jaydeep Chaudhuri, Sanjit Kumar Mahato, Anirban Manna, Roma Sinha, Prayot Bhattacharya, Jayaraman Vinayagam, Deba Prasad Jana, Sushovan Chowdhury
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Patent number: 8519154Abstract: The present invention relates to a method for the treatment of bronchial asthma and chronic obstructive pulmonary disease (COPD) comprising administering to the patient suffering from asthma and COPD an effective dose of carbazole derivatives or salt thereof, optionally along with pharmaceutically acceptable excipients. Structural formula of the compounds of general formula 1 useful as phosphodiesterase-4 (PDE-4) enzyme inhibitors, inhibitor for signalling molecule for the treatment of asthma and asthma related diseases is given below: wherein R1=H or OCH3; R2?CH3 or CHO; R3?H or OCH3; R4?H or OCH3 Herbal route for the isolation of compound of general formula 1 from the bark of plant Murraya Koenigii and chemical route for the preparation of such compounds from basic compounds such as vanillin is also reported.Type: GrantFiled: February 3, 2012Date of Patent: August 27, 2013Assignee: Council of Scientific & Industrial ResearchInventors: Sibabrata Mukhopadhyay, Mumu Chakraborty, Tulika Mukherjee, Arun Bandyopadhyay, Dipak Kar, Tanima Banerjee, Aditya Konar, Debaprasad Jana, Siddhartha Roy, Santu Bandyopadhyay, Balram Ghosh, Mabalirajan Ulaganathan, Rakesh Kamal Johri, Subhash Chander Sharma, Gurdarshan Singh, Bholanath Paul, Vasanta Madhava Sharma Gangavaram, Jhillu Singh Yadav, Radha Krishna Palakodety
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Publication number: 20120202868Abstract: The present invention relates to a method for the treatment of bronchial asthma and chronic obstructive pulmonary disease (COPD) comprising administering to the patient suffering from asthama and COPD an effective dose of carbazole derivatives or salt thereof, optionally along with pharmaceutically acceptable excipients. Structural formula of the compounds of general formula 1 useful as phosphodiesterase-4 (PDE-4) enzyme inhibitors, inhibitor for signalling molecule for the treatment of asthma and asthma related diseases is given below: wherein R1=H or OCH3; R2?CH3 or CHO; R3?H or OCH3; R4?H or OCH3 Herbal route for the isolation of compound of general formula 1 from the bark of plant Murraya Koenigii and chemical route for the preparation of such compounds from basic compounds such as vanillin is also reported.Type: ApplicationFiled: February 3, 2012Publication date: August 9, 2012Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Sibabrata MUKHOPADHYAY, Mumu CHAKRABORTY, Tulika MUKHERJEE, Arun BANDYOPADHYAY, Dipak KAR, Tanima BANERJEE, Aditya KONAR, Debaprasad JANA, Siddhartha ROY, Santu BANDYOPADHYAY, Balram GHOSH, Mabalirajan ULAGANATHAN, Rakesh Kamal JOHRI, Subhash Chander SHARMA, Gurdarshan SINGH, Bholanath PAUL, Vasanta Madhava Sharma GANGAVARAM, Jhillu Singh YADAV, Radha Krishna PALAKODETY
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Publication number: 20120190738Abstract: The present invention relates to compounds of general formula I for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention also relates to the use of compound of general formula I for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention further relates to a method of treating malignancy by inhibition of PI3-Akt pathway and or induction of NO by administration of compound or said composition to a mammal in need thereof.Type: ApplicationFiled: January 12, 2010Publication date: July 26, 2012Inventors: Santu Bandyopadhyay, Bikas Chandra Pal, Jaisankar Parasuraman, Siddhartha Roy, Jayashree Bagchi Chakrabotry, Indrani Choudhury Mukherjee, Sanjit Kumar Mahato, Aditya Konar, Srabanti Rakshit, Labanya Mandal, Dipyaman Ganguly, Kausik Paul, Anirban Manna, Jayaraman Vinayagam, Churala Pal
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Patent number: 7276258Abstract: The present invention relates to a method of preventing and/or treating diabetes type 2, also, it relates to a method of augmenting Glut4 phosphorylation and Glut4 translocation to a target cell membrane to enhance insulin signal in a signal transduction pathway; further, it relates to a simplified and inexpensive process of obtaining extract and thereafter selectively, its active n-butanol fraction and active molecule Lupinoside PA (LPA4), useful in preventing and/or treating diabetes type 2; and lastly, a pharmaceutical composition thereof.Type: GrantFiled: March 25, 2004Date of Patent: October 2, 2007Assignee: Council of Scientific & Industrial ResearchInventors: Debleena Dey, Swapan Kumar Mandal, Mohua Mukherjee, Bikash Chandra Pal, Tanushree Biswas, Malabika Datta, Sib Sankar Roy, Arun Bandyopadhyay, Samir Bhattacharya, Bir Bhanu Giri, Santu Bandopadhyay, Aditya Konar
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Publication number: 20070161704Abstract: This invention relates to a pharmaceutical composition useful for treating chronic myeloid leukemia where Bcr-Abl kinase is constitutively expressed in animals and humans, and a treatment of chronic myeloid leukemia (CML) by a composition comprising an effective amount of analogs and/or salts of chlorogenic acid. The analogs are preferably sodium chlorogenate (Na-Chl) or potassium or ammonium salts, which were prepared from Chlorogenic acid or its analogs.Type: ApplicationFiled: December 18, 2006Publication date: July 12, 2007Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Santu Bandyopadhyay, Bikas Pal, Samir Bhattacharyay, Swapan Mondal, Chhabinath Mandal, Aditya Konar, Keshab Roy, Tanusree Biswas, Gautam Bandyopadhyay
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Publication number: 20050282892Abstract: This invention relates to a pharmaceutical composition useful for treating chronic myeloid leukemia where Bcr-Abl kinase is constitutively expressed in animals and humans, and a treatment of chronic myeloid leukemia (CML) by a composition comprising an effective amount of analogs and/or salts of chlorogenic acid. The analogs are preferably sodium chlorogenate (Na-Chl) or potassium or ammonium salts, which were prepared from Chlorogenic acid or its analogs.Type: ApplicationFiled: July 6, 2005Publication date: December 22, 2005Inventors: Santu Bandyopadhyay, Bikas Pal, Samir Bhattacharyay, Swapan Mondal, Chhabinath Mandal, Aditya Konar, Keshab Roy, Tanusree Biswas, Gautam Bandyopadhyay
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Publication number: 20050153000Abstract: The present invention relates to a method of preventing and/or treating diabetes type 2, also, it relates to a method of augmenting Glut4 phosphorylation and Glut4 translocation to a target cell membrane to enhance insulin signal in a signal transduction pathway; further, it relates to a simplified and inexpensive process of obtaining extract and thereafter selectively, its active n-butanol fraction and active molecule Lupinoside PA (LPA4), useful in preventing and/or treating diabetes type 2; and lastly, a pharmaceutical composition thereof.Type: ApplicationFiled: March 25, 2004Publication date: July 14, 2005Applicant: Council Of Scientific & Industrial ResearchInventors: Debleena Dey, Swapan Mandal, Mohua Mukherjee, Bikash Pal, Tanushree Biswas, Malabika Datta, Sib Roy, Arun Bandyopadhyay, Samir Bhattacharya, B. Giri, Santu Bandopadhyay, Aditya Konar
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Publication number: 20040006138Abstract: The present invention relates to a pharmaceutical composition useful for treating chronic myeloid leukemia where Bcr-Abl kinase is constitutively expressed in animals and humans, said composition comprising an effective amount of analogs of chlorogenic acid such as neochlorogenic acid (5-O-caffeoyl quinic acid), cryptochlorogenic acid (4-O-Caffeoyl quinic acid), 3-O-(3′-methylcaffeoyl) quinic acid and 5-O-(Caffeoyl-4′-methyl) quinic acid and/or its salts such as sodium, potassium and ammonium together with pharmaceutically acceptable additives.Type: ApplicationFiled: January 9, 2003Publication date: January 8, 2004Applicants: COUNCIL OF SCIENTIFIC, INDUSTRIAL RESEARCHInventors: Santu Bandyopadhyay, Bikas Chandra Pal, Samir Bhattacharyay, Swapan Mondal, Chhabinath Mandal, Aditya Konar, Keshab Chandra Roy, Tanusree Biswas, Gautam Bandyopadhyay