Patents by Inventor Aditya PATWA

Aditya PATWA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Asymmetric synthesis of alpha-branched chiral amines
    Patent number: 11279672
    Abstract: The present invention relates to an improved asymmetric synthesis of alpha-branched amines (hereafter referred to as the compound) and relative chiral amines (1?) or its pharmaceutically acceptable salt and derivatives. The process comprises an unusual substrate specific regioselective ortho lithiation of substituted arene compounds, followed by its highly diastereoselective addition to N-tert-butanesulfinylimines resulting in the selective formation of alpha-branched sulfinyl amine and chiral amine; which on subsequently removing the sulfinyl group provides corresponding alpha-branched amines or relative chiral amines (1?).
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: March 22, 2022
    Assignee: PIRAMAL PHARMA LIMITED
    Inventors: Rajender Reddy Leleti, Sharadsrikar Kotturi, Yogesh Waman, Chirag Patel, Aditya Patwa, Rajesh Shenoy
  • AN IMPROVED ASYMMETRIC SYNTHESIS OF alpha-BRANCHED CHIRAL AMINES
    Publication number: 20210114977
    Abstract: The present invention relates to an improved asymmetric synthesis of alpha-branched amines (hereafter referred to as the compound) and relative chiral amines (1?) or its pharmaceutically acceptable salt and derivatives. The process comprises an unusual substrate specific regioselective ortho lithiation of substituted arene compounds, followed by its highly diastereoselective addition to N-tert-butanesulfinylimines resulting in the selective formation of alpha-branched sulfinyl amine and chiral amine; which on subsequently removing the sulfinyl group provides corresponding alpha-branched amines or relative chiral amines (1?).
    Type: Application
    Filed: April 17, 2019
    Publication date: April 22, 2021
    Applicant: PIRAMAL ENTERPRISES LIMITED
    Inventors: Rajender Reddy LELETI, Sharadsrikar KOTTURI, Yogesh WAMAN, Chirag PATEL, Aditya PATWA, Rajesh SHENOY