Patents by Inventor Admassu Abebe

Admassu Abebe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL FORMULATIONS OF INDOLEAMINE 2, 3-DIOXYGENASE INHIBITORS
    Publication number: 20240122857
    Abstract: The present application is directed to a pharmaceutical composition comprising (R)—N-(4-chlorophenyl)-2-((1S, 4S)-4-(6-fluoroquinolin-4-yl) cyclohexyl) propanamide methane sulfonic acid salt that is resistant to salt disproportionation:
    Type: Application
    Filed: September 10, 2020
    Publication date: April 18, 2024
    Inventors: Jing TAO, Anisha PATEL, Umesh KESTUR, Admassu ABEBE, Divyakant Shantilal DESAI
  • BILAYER TABLET FORMULATIONS
    Publication number: 20170333353
    Abstract: The present invention relates to bilayer tablet formulations comprising metformin extended release (XR) or reduced mass metformin XR formulation as the first layer, an SGLT2 inhibitor formulation as the second layer, and optionally a film coating. The present invention provides methods of preparing the bilayer tablet formulations and methods of treating diseases or disorders associated with SGLT2 activity employing the bilayer tablet formulations.
    Type: Application
    Filed: March 6, 2017
    Publication date: November 23, 2017
    Inventors: Admassu Abebe, Kyle Martin, Jatin M. Patel, Divyakant Desai, Peter Timmins
  • Bilayer tablet formulations
    Patent number: 9616028
    Abstract: The present invention relates to bilayer tablet formulations comprising metformin extended release (XR) or reduced mass metformin XR formulation as the first layer, an SGLT2 inhibitor formulation as the second layer, and optionally a film coating. The present invention provides methods of preparing the bilayer tablet formulations and methods of treating diseases or disorders associated with SGLT2 activity employing the bilayer tablet formulations.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: April 11, 2017
    Assignees: AstraZeneca AB, AstraZeneca UK Limited
    Inventors: Admassu Abebe, Kyle Martin, Jatin M. Patel, Divyakant Desai, Peter Timmins
  • Bilayer Tablet Formulations
    Publication number: 20150238421
    Abstract: The present invention relates to bilayer tablet formulations comprising metformin extended release (XR) or reduced mass metformin XR formulation as the first layer, an SGLT2 inhibitor formulation as the second layer, and optionally a film coating. The present invention provides methods of preparing the bilayer tablet formulations and methods of treating diseases or disorders associated with SGLT2 activity employing the bilayer tablet formulations.
    Type: Application
    Filed: May 7, 2015
    Publication date: August 27, 2015
    Inventors: Admassu Abebe, Kyle Martin, Jatin M. Patel, Divyakant Desai, Peter Timmins
  • Bilayer tablet formulations
    Patent number: 9050258
    Abstract: The present invention relates to bilayer tablet formulations comprising metformin extended release (XR) or reduced mass metformin XR formulation as the first layer, an SGLT2 inhibitor formulation as the second layer, and optionally a film coating. The present invention provides methods of preparing the bilayer tablet formulations and methods of treating diseases or disorders associated with SGLT2 activity employing the bilayer tablet formulations.
    Type: Grant
    Filed: August 13, 2013
    Date of Patent: June 9, 2015
    Assignee: AstraZeneca AB
    Inventors: Admassu Abebe, Kyle Martin, Jatin M. Patel, Divyakant Desai, Peter Timmins
  • Reduced Mass Metformin Formulations
    Publication number: 20140335170
    Abstract: The present invention relates to metformin extended release (XR) formulations with improved compactability to provide reduced mass tablets, granulations, and capsules.
    Type: Application
    Filed: May 6, 2014
    Publication date: November 13, 2014
    Applicant: Bristol-Myers Squibb Company
    Inventors: Admassu Abebe, Kyle Martin, Jatin M. Patel, Peter Timmins
  • Bilayer Tablet Formulations
    Publication number: 20130330406
    Abstract: The present invention relates to bilayer tablet formulations comprising metformin extended release (XR) or reduced mass metformin XR formulation as the first layer, an SGLT2 inhibitor formulation as the second layer, and optionally a film coating. The present invention provides methods of preparing the bilayer tablet formulations and methods of treating diseases or disorders associated with SGLT2 activity employing the bilayer tablet formulations.
    Type: Application
    Filed: August 13, 2013
    Publication date: December 12, 2013
    Applicants: AstraZeneca UK Limited, Bristol-Myers Squibb Company
    Inventors: Admassu Abebe, Kyle Martin, Jatin M. Patel, Divyakant Desai, Peter Timmins
  • Bilayer tablet formulations
    Patent number: 8535715
    Abstract: The present invention relates to bilayer tablet formulations comprising metformin extended release (XR) or reduced mass metformin XR formulation as the first layer, an SGLT2 inhibitor formulation as the second layer, and optionally a film coating. The present invention provides methods of preparing the bilayer tablet formulations and methods of treating diseases or disorders associated with SGLT2 activity employing the bilayer tablet formulations.
    Type: Grant
    Filed: November 12, 2010
    Date of Patent: September 17, 2013
    Assignees: Bristol-Myers Squibb Company, AstraZeneca UK Limited
    Inventors: Admassu Abebe, Kyle Martin, Jatin M. Patel, Divyakant Desai, Peter Timmins
  • REDUCED MASS METFORMIN FORMULATIONS
    Publication number: 20120294936
    Abstract: The present invention relates to metformin extended release (XR) formulations with improved compactability to provide reduced mass tablets, granulations, and capsules.
    Type: Application
    Filed: November 12, 2010
    Publication date: November 22, 2012
    Applicants: ASTRAZENECA UK LIMITED, BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Admassu Abebe, Kyle Martin, Jatin M. Patel, Peter Timmins
  • BILAYER TABLET FORMULATIONS
    Publication number: 20120282336
    Abstract: The present invention relates to bilayer tablet formulations comprising metformin extended release (XR) or reduced mass metformin XR formulation as the first layer, an SGLT2 inhibitor formulation as the second layer, and optionally a film coating. The present invention provides methods of preparing the bilayer tablet formulations and methods of treating diseases or disorders associated with SGLT2 activity employing the bilayer tablet formulations.
    Type: Application
    Filed: November 12, 2010
    Publication date: November 8, 2012
    Applicants: ASTRAZENECA UK LIMITED, BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Admassu Abebe, Kyle Martin, Jatin M. Patel, Divyakant Desai, Peter Timmins
  • Multilayered tablet containing pravastatin and aspirin and method
    Publication number: 20040115265
    Abstract: A multilayered tablet having three or more layers is provided which is useful for cholesterol lowering and reducing the risk of a myocardial infarction, which includes a first layer containing aspirin, another layer containing pravastatin, and a middle barrier layer, which preferably contains a buffering agent, which separates the first layer containing aspirin from the other layer containing pravastatin, and prevents or minimizes interaction of aspirin with pravastatin. A method for lowering cholesterol and reducing risk of a myocardial infarction employing such composition is also provided.
    Type: Application
    Filed: December 11, 2002
    Publication date: June 17, 2004
    Inventors: Loutfy Benkerrour, Olivier Galley, Francoise Quinet, Admassu Abebe, Peter Timmins