Patents by Inventor Ado Kaiser

Ado Kaiser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4581172
    Abstract: Pyrimidone derivatives of the formula ##STR1## wherein n is the integer 1 or 0; A.sup.1 and A.sup.2 are independently methylene or mono-lower alkyl or di-lower alkyl methylene; X is methylene, mono-lower alkyl or di-lower alkyl methylene, nitrogen or lower alkyl nitrogen; R is hydrogen or lower alkyl; and Y and Z taken together are the group .dbd.NR.sup.5, or R and Z taken together form a N--C--bond and Y is a group --N(H)R.sup.5 ; R.sup.1, R.sup.2 and R.sup.3 are hydrogen, lower alkyl or lower alkoxy, or R.sup.1 and R.sup.2 or R.sup.2 and R.sup.3 taken together are methylenedioxy or ethylenedioxy; R.sup.4 is hydrogen or lower-alkyl; R.sup.5 is phenyl or phenyl substituted by one or more of R.sup.6, R.sup.7 and R.sup.8 which, independently, are chlorine, fluorine, bromine, lower-alkyl or lower-alkoxy; and provided that at least one of the methylene groups A.sup.1 and A.sup.2 is mono-lower alkyl or di-lower alkyl methylene, when R.sup.
    Type: Grant
    Filed: April 25, 1984
    Date of Patent: April 8, 1986
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ado Kaiser, Frank Kienzle
  • Patent number: 4390540
    Abstract: Imidazoquinazolines of the formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are hydrogen, halogen, C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy or C.sub.2-5 -alkoxyalkyl; or two of R.sup.1, R.sup.2 and R.sup.3 on adjacent carbon atoms taken together are methylenedioxy or ethylenedioxy; and R.sup.4 and R.sup.5 are hydrogen or C.sub.1-4 -alkyl,and their tautomers, as well as their physiologically compatible acid addition salts, are described.The compounds of formula I inhibit the aggregation of the blood platelets, as well as gastric acid secretion, and have activity on the circulatory system.
    Type: Grant
    Filed: August 12, 1981
    Date of Patent: June 28, 1983
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Madhukar S. Chodnekar, Ado Kaiser, Frank Kienzle
  • Patent number: 4256748
    Abstract: Compounds of the formula ##STR1## wherein R.sup.1,R.sup.2,R.sup.3 and R.sup.4 are as hereinafter described, tautomers and salts thereof, are disclosed. The foregoing compounds inhibit the aggregation of blood platelets which renders them useful as therapeutic agents in the prophylaxis of thromboses. Furthermore, they are useful for the treatment and prophylaxis of cardiac insufficiency and cardiac failure, due to their inotropic activity without substantial tachycardia.
    Type: Grant
    Filed: June 20, 1979
    Date of Patent: March 17, 1981
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Madhukar S. Chodnekar, Ado Kaiser
  • Patent number: 4202832
    Abstract: Thiocarbamoylthio fatty acid derivatives of the formula ##STR1## wherein R.sup.1, R.sup.2, A, Y and n are as hereinafter set forth, are described. The compounds of formula I are useful as lipid-lowering agents.
    Type: Grant
    Filed: October 20, 1978
    Date of Patent: May 13, 1980
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ulf Fischer, Ado Kaiser
  • Patent number: 3969397
    Abstract: The present invention is directed to preparing L-Dopa, an agent effective in the treatment of Parkinson's Disease, from a D,L-N-benzoyl-3-(4-hydroxy-3-methoxyphenyl) alanine utilizing dehydroabietylamine as a resolving agent and intermediates in this process.
    Type: Grant
    Filed: December 11, 1969
    Date of Patent: July 13, 1976
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ado Kaiser, Marcel Scheer, Werner Hausermann, Leo Marti
  • Patent number: 3933859
    Abstract: Process for obtaining 5,6 or 6,7 or 7,8 dihydroxy coumarin or derivatives thereof, which are useful for lower blood pressure and for chemical sympathectomy by oxidizing 2,3 or 3,4 or 4,5 dihydroxyphenyl-propionic acid or derivatives thereof, and novel coumarin derivatives of the process.
    Type: Grant
    Filed: June 12, 1974
    Date of Patent: January 20, 1976
    Assignee: Hoffmann-La Roche, Inc.
    Inventors: Ado Kaiser, Wolfgang Koch, Marcel Scheer, Uwe Wolcke
  • Patent number: 3931268
    Abstract: Benzene-ring substituted (2-methylhydrazino)methylbenzene compounds and intermediates therefor are described. The former compounds are useful as cytostatic agents.
    Type: Grant
    Filed: May 6, 1970
    Date of Patent: January 6, 1976
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Werner Bollag, Hugo Gutmann, Balthasar Hegedus, Ado Kaiser, Albert Langemann, Marcel Muller, Paul Zeller