Abstract: A microscope slide-holder support having a plate-shaped body defining an upper body surface, an opposite lower body surface, and a body thickness defined between the upper body surface and the lower body surface is provided. The plate-shaped body has a through opening passing through the plate-shaped body between the upper body surface and the lower body surface, at least one slide seat to removably house a corresponding microscope slide at the upper body surface, and upper removable engagement means for engaging/disengaging the microscope slide to/from the plate-shaped body at a respective slide seat. The microscope slide-holder support has a collection plate coupable to the plate-shaped body for at least partially closing the through opening close to the lower body surface, the collection plate and the through opening being configured to jointly form a collection compartment in the microscope slide-holder support.

Abstract: This patent application pertains to the optical laser microscopy field and proposes a simplified yet specific optical laser coupling method. The proposed method allows for a sensible reduction in size and complexity of laser based microscopes and related applications, especially in the area of nano particles detection and optical biosensing. Particularly the optical laser coupling proposed method can detect optical signals generated from sub-diffractive nanoparticles located in liquid solution on a standard glass coverslip. Thanks to the small size of the required components and to the usage of standard air-lens objective, without the presence of oil or special prism, this method can be easily embedded into a small, lightweight and portable device, which can properly operate even in absence of gravity.

Abstract: This patent application pertains to the optical laser microscopy field and proposes a simplified yet specific optical laser coupling method. The proposed method allows for a sensible reduction in size and complexity of laser based microscopes and related applications, especially in the area of nano particles detection and optical biosensing. Particularly the optical laser coupling proposed method can detect optical signals generated from sub-diffractive nanoparticles located in liquid solution on a standard glass coverslip. Thanks to the small size of the required components and to the usage of standard air-lens objective, without the presence of oil or special prism, this method can be easily embedded into a small, lightweight and portable device, which can properly operate even in absence of gravity.