Patents by Inventor Adolfo Garcia OCAÑA

Adolfo Garcia OCAÑA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Kinase inhibitor compounds and compositions and methods of use
    Patent number: 11866427
    Abstract: Described herein are compounds having the following structure: formula (I) or a stereoisomer, pharmaceutically acceptable salt, oxide, or solvate thereof. Also disclosed are compositions containing the compounds, methods of inhibiting activity of DYRK1 A in a cell, methods of increasing cell proliferation in a population of pancreatic beta cells, methods of treating a subject for a condition associated with insufficient insulin secretion, and methods of treating a subject for a neurological disorder.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: January 9, 2024
    Assignee: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
    Inventors: Kunal Kumar, Peng Wang, Roberto Sanchez, Adolfo Garcia Ocaña, Andrew Stewart, Robert Devita
  • KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE
    Publication number: 20210094950
    Abstract: Described herein are compounds having the following structure: formula (I) or a stereoisomer, pharmaceutically acceptable salt, oxide, or solvate thereof. Also disclosed are compositions containing the compounds, methods of inhibiting activity of DYRK1 A in a cell, methods of increasing cell proliferation in a population of pancreatic beta cells, methods of treating a subject for a condition associated with insufficient insulin secretion, and methods of treating a subject for a neurological disorder.
    Type: Application
    Filed: March 20, 2019
    Publication date: April 1, 2021
    Inventors: Kunal KUMAR, Peng WANG, Roberto SANCHEZ, Adolfo Garcia OCAÑA, Andrew STEWART, Robert DEVITA