Patents by Inventor Adolphus van Loon
Adolphus van Loon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20080220118Abstract: The present invention relates to phytase variants, their preparation and uses, which phytase variants, when aligned according to FIG. 1, are amended as compared to a model phytase in at least one of a number of positions. Preferred model phytases are basidiomycete and ascomycete phytases, such as Peniophora phytase and Aspergillus phytases. Preferred phytase variants exhibits amended activity characteristics, such as improved specific activity and/or improved thermostability.Type: ApplicationFiled: November 19, 2007Publication date: September 11, 2008Applicant: Novozymes A/SInventors: Allan Svendsen, Soren Flensted Lassen, Dirk Kostrewa, Luis Pasamontes, Martin Lehman, Andrea Tomschy, Adolphus Van Loon, Kurt Vogel, Markus Wyss
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Publication number: 20080219965Abstract: The present invention relates to phytase variants, their preparation and uses, which phytase variants, when aligned according to FIG. 1, are amended as compared to a model phytase in at least one of a number of positions. Preferred model phytases are basidiomycete and ascomycete phytases, such as Peniophora phytase and Aspergillus phytases. Preferred phytase variants exhibits amended activity characteristics, such as improved specific activity and/or improved thermostability.Type: ApplicationFiled: November 19, 2007Publication date: September 11, 2008Applicant: Novozymes A/SInventors: Allan Svendsen, Soren Flensted Lassen, Dirk Kostrewa, Luis Pasamontes, Martin Lehmann, Andrea Tomschy, Adolphus Van Loon, Kurt Vogel, Markus Wyss
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Patent number: 7326554Abstract: The present invention relates to phytase variants, their preparation and uses, which phytase variants, when aligned according to FIG. 1, are amended as compared to a model phytase in at least one of a number of positions. Preferred model phytases are basidiomycete and ascomycete phytases, such as Peniophora phytase and Aspergillus phytases. Preferred phytase variants exhibits amended activity characteristics, such as improved specific activity and/or improved thermostability.Type: GrantFiled: December 12, 2003Date of Patent: February 5, 2008Assignee: Novozymes AlsInventors: Allan Svendsen, Soren Flensted Lassen, Dirk Kostrewa, Luis Pasamontes, Martin Lehman, Andrea Tomschy, Adolphus Van Loon, Kurt Vogel, Markus Wyss
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Patent number: 7078183Abstract: A process for the production of a modified phytase with a desired property improved over the property of the corresponding unmodified phytase is disclosed, as well as modified phytases, polynucleotides encoding modified phytases, and animal feed including modified phytases.Type: GrantFiled: February 11, 2004Date of Patent: July 18, 2006Assignee: DSM IP Assets B.V.Inventors: Dirk Kostrewa, Luis Pasamontes, Andrea Tomschy, Adolphus van Loon, Kurt Vogel, Markus Wyss
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Publication number: 20040175376Abstract: The present invention relates to phytase variants, their preparation and uses, which phytase variants, when aligned according to FIG. 1, are amended as compared to a model phytase in at least one of a number of positions. Preferred model phytases are basidiomycete and ascomycete phytases, such as Peniophora phytase and Aspergillus phytases. Preferred phytase variants exhibits amended activity characteristics, such as improved specific activity and/or improved thermostability.Type: ApplicationFiled: December 12, 2003Publication date: September 9, 2004Applicant: Novozymes A/SInventors: Allan Svendsen, Soren Flensted Lassen, Dirk Kostrewa, Luis Pasamontes, Martin Lehmann, Andrea Tomschy, Adolphus Van Loon, Kurt Vogel, Markus Wyss
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Publication number: 20040142424Abstract: A process for the production of a modified phytase with a desired property improved over the property of the corresponding unmodified phytase is disclosed, as well as modified phytases, polynucleotides encoding modified phytases, and animal feed including modified phytases.Type: ApplicationFiled: February 11, 2004Publication date: July 22, 2004Applicant: ROCHE VITAMINS INC.Inventors: Dirk Kostrewa, Luis Pasamontes, Andrea Tomschy, Adolphus van Loon, Kurt Vogel, Markus Wyss
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Patent number: 6734004Abstract: A process for the production of a modified phytase with a desired property improved over the property of the corresponding unmodified phytase is disclosed, as well as modified phytases, polynucleotides encoding modified phytases, and animal feed including modified phytases.Type: GrantFiled: February 1, 2002Date of Patent: May 11, 2004Assignee: Roche Vitamins Inc.Inventors: Dirk Kostrewa, Luis Pasamontes, Andrea Tomschy, Adolphus van Loon, Kurt Vogel, Markus Wyss
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Patent number: 6699704Abstract: The present invention relates to heat tolerant phytases and DNA sequences which code therefor. The phytases are useful in hydrolyzing phytate to inositol and inorganic phosphates. The phytases are valuable feed additives.Type: GrantFiled: August 9, 2000Date of Patent: March 2, 2004Assignee: Roche Vitamins Inc.Inventors: Adolphus van Loon, David Mitchell
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Patent number: 6689358Abstract: The present invention relates to phytase variants, their preparation and uses, which phytase variants, when aligned according to FIG. 1, are amended as compared to a model phytase in at least one of a number of positions. Preferred model phytases are basidiomycete and ascomycete phytases, such as Peniophora phytase and Aspergillus phytases. Preferred phytase variants exhibits amended activity characteristics, such as improved specific activity and/or improved thermostability.Type: GrantFiled: February 26, 2002Date of Patent: February 10, 2004Assignee: Novozymes A/SInventors: Allan Svendsen, Søren Flensted Lassen, Dirk Kostrewa, Luis Pasamontes, Martin Lehmann, Andrea Tomschy, Adolphus Van Loon, Kurt Vogel, Markus Wyss
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Patent number: 6613543Abstract: Novel proteins of Flavobacterium sp. R1534 and the DNA sequences which encode these proteins are disclosed which provide an improved biosynthetic pathway from farnesyl pyrophosphate and isopentyl pyrophosphate to various carotenoid precursors and carotenoids, especially &bgr;-carotene, lycopene, zeaxanthin and cantaxanthin.Type: GrantFiled: April 11, 2000Date of Patent: September 2, 2003Assignee: Roche Vitamins, Inc.Inventors: Hans-Peter Hohmann, Luis Pasamontes, Michel Tessier, Adolphus van Loon
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Publication number: 20030092155Abstract: A process for the production of a modified phytase with a desired property improved over the property of the corresponding unmodified phytase is disclosed, as well as modified phytases, polynucleotides encoding modified phytases, and animal feed including modified phytases.Type: ApplicationFiled: February 1, 2002Publication date: May 15, 2003Applicant: ROCHE VITAMINS INC.Inventors: Dirk Kostrewa, Luis Pasamontes, Andrea Tomschy, Adolphus van Loon, Kurt Vogel, Markus Wyss
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Patent number: 6514495Abstract: Phytase variants, their preparation and uses, which phytase variants, when aligned according to FIG. 1, are amended as compared to a model phytase in at least one of a number of positions. Preferred model phytases are basidiomycete and ascomycete phytases, such as Peniophora phytase and Aspergillus phytases. Preferred phytase variants exhibits amended activity characteristics, such as improved specific activity and/or improved thermostability.Type: GrantFiled: March 22, 1999Date of Patent: February 4, 2003Assignee: Novozymes A/SInventors: Allan Svendsen, Søren Flensted Lassen, Dirk Kostrewa, Luis Pasamontes, Martin Lehmann, Andrea Tomschy, Adolphus Van Loon, Kurt Vogel, Markus Wyss
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Publication number: 20020147371Abstract: Novel proteins of Flavobacterium sp. R1534 and the DNA sequences which encode these proteins are disclosed which provide an improved biosynthetic pathway from famesyl pyrophosphate and isopentyl pyrophosphate to various carotenoid precursors and carotenoids, especially &bgr;-carotene, lycopene, zeaxanthin and cantaxanthin.Type: ApplicationFiled: April 11, 2000Publication date: October 10, 2002Inventors: Hans-Peter Hohmann, Luis Pasamontes, Michel Tessier, Adolphus van Loon
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Publication number: 20020127218Abstract: The present invention relates to phytase variants, their preparation and uses, which phytase variants, when aligned according to FIG. 1, are amended as compared to a model phytase in at least one of a number of positions. Preferred model phytases are basidiomycete and ascomycete phytases, such as Peniophora phytase and Aspergillus phytases. Preferred phytase variants exhibits amended activity characteristics, such as improved specific activity and/or improved thermostability.Type: ApplicationFiled: February 26, 2002Publication date: September 12, 2002Applicant: Novozymes A/SInventors: Allan Svendsen, Soren Flensted Lassen, Dirk Kostrewa, Luis Pasamontes, Martin Lehman, Andrea Tomschy, Adolphus Van Loon, Kurt Vogel, Markus Wyss
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Patent number: 6391605Abstract: A process for the production of a modified phytase with a desired property improved over the property of the corresponding unmodified phytase is disclosed, as well as modified phytases, polynucleotides encoding modified phytases, and animal feed including modified phytases.Type: GrantFiled: March 19, 1998Date of Patent: May 21, 2002Assignee: Roche Vitamins Inc.Inventors: Dirk Kostrewa, Luis Pasamontes, Andrea Tomschy, Adolphus van Loon, Kurt Vogel, Markus Wyss
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Patent number: 6376222Abstract: The present invention provides a transformed yeast strain containing a DNA sequence transcriptionally linked to a promoter functional in such yeast cells, which when expressed in a suitable host cell, encodes at least one polypeptide having riboflavin biosynthetic activity. Using such transformants, improved levels of riboflavin production are achieved. Processes of producing riboflavin from such transformants are also provided.Type: GrantFiled: April 23, 1999Date of Patent: April 23, 2002Assignee: Roche Vitamins, Inc.Inventors: Lyubov Ya. Babyak, Adelbert Bacher, Yuriy R. Boretskyy, Vasyl V. Demchyshyn, Sabine Eberhardt, Dariya Fedorovych, Holger Lüttgen, Gerald Richter, Adolphus van Loon
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Patent number: 6358722Abstract: The present invention relates to heat tolerant phytases and DNA sequences which code therefor. The phytases are useful in hydrolyzing phytate to inositol and inorganic phosphates. The phytases are valuable feed additives.Type: GrantFiled: November 5, 1996Date of Patent: March 19, 2002Assignee: Roche Vitamins, Inc.Inventors: Adolphus van Loon, David Mitchell
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Patent number: 6322995Abstract: The present invention provides a recombinant bacterium for the over-production of riboflavin. The recombinant bacterium has has been transformed by three or four vectors, two of which each comprise either a DNA sequence coding for the riboflavin synthesizing enzymatic activities of Bacillus subtilis or a DNA sequence which is substantially homologous and one or more transcription elements and a third and/or fourth vector comprising either a DNA sequence coding for the ribA gene product of Bacillus subtilis or a DNA sequence which is substantially homologous and optionally a transcription element whereby one or a plurality of copies of each of these vectors has/have been integrated at three or four different sites within the bacterium's chromosome.Type: GrantFiled: July 23, 1997Date of Patent: November 27, 2001Assignee: F. Hoffmann-La Roche AGInventors: Hans-Peter Hohmann, Markus Hümbelin, Adolphus van Loon, Walter Schurter
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Patent number: 6291221Abstract: The present invention relates to heat tolerant phytases and DNA sequences which code therefor. The phytases are useful in hydrolyzing phytate to inositol and inorganic phosphates. The phytases are valuable feed additives.Type: GrantFiled: June 3, 1997Date of Patent: September 18, 2001Assignee: Roche Vitamins Inc.Inventors: Adolphus van Loon, David Mitchell
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Patent number: 6207409Abstract: Novel proteins of Flavobacterium sp. R1534 and the DNA sequences which encode these proteins are disclosed which provide an improved biosynthetic pathway from farnesyl pyrophosphate and isopentyl pyrophosphate to various carotenoid precursors and carotenoids, especially &bgr;-carotene, lycopene, zeaxanthin and cantaxanthin.Type: GrantFiled: April 11, 2000Date of Patent: March 27, 2001Assignee: Roche Vitamins Inc.Inventors: Hans-Peter Hohmann, Luis Pasamontes, Michel Tessier, Adolphus van Loon