Abstract: Therapeutics and methods of diagnosing non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) in a patient comprising obtaining a sample from the patient, determining a level of a signaling lymphocytic activation molecule 1 (SLAMF1) in the sample from the patient, and diagnosing the patient with NAFLD when the level of the SLAMF1 is at least an elevated threshold level for the SLAMF1. Therapeutics and methods of treating non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) in a patient in need of treatment comprising administering a pharmaceutically effective dose of a therapeutic, wherein the therapeutic includes a signaling lymphocytic activation molecule 1 (SLAMF1) antagonist.

Abstract: Disclosed herein are system, method, and computer program product embodiments for a dynamic email system. An embodiment operates by assigning a persona record to a subscriber record in a set of subscriber records based on a characteristic of the subscriber record. The embodiment assigns a content score to a content item in a content database based on subscriber engagement data associated with the content item. The embodiment ranks the content item in the content database based on the content score assigned to the content item. The embodiment assigns the content item to the subscriber record based on a characteristic of the content item, the content score assigned to the content item, or the persona record. The embodiment creates an email comprising the content item based on the assignment of the content item to the subscriber record. The embodiment sends the email to an email address associated with the subscriber record.

Abstract: According to some embodiments, a method of flashing a jacketed rail car comprises covering an opening in a tank jacket of a rail car with a first flashing piece. The opening permits a fitting to protrude through the jacket. The fitting comprises a base portion of a first perimeter and a top flanged portion of a second perimeter. The first flashing piece comprises a slot. The method further comprises bonding the first flashing piece to the jacket and to the base portion of the fitting, and bonding a vertical support piece to the tank shell. The vertical support piece extends through the slot in the first flashing piece. The method further comprises bonding the vertical support piece to the top flanged portion of the fitting; covering the slot with a second flashing piece; and bonding the second flashing piece to the first flashing piece and the vertical support piece.

Abstract: In one embodiment, a method includes enrolling a potential enrollee for an identity-monitoring service. The enrolling includes acquiring personally-identifying information (PII) and capturing a voiceprint. Following successful completion of the enrolling, the potential enrollee is an enrollee. The method further includes, responsive to an identified suspicious event related to the PII, creating an identity alert, establishing voice communication with an individual purporting to be the enrollee, and performing voice-biometric verification of the individual. The voice-biometric verification includes comparing one or more spoken utterances with the voiceprint. Following successful completion of the voice-biometric verification, the individual is a verified enrollee. In addition, the method includes authorizing delivery of the identity alert to the verified enrollee.

Abstract: An authoring, execution, and participation software system and corresponding method for the capture and execution of real-world events (e.g., crises) involving individuals such as senior private and/or public sector leaders is presented. The authoring system and method are used to model a scenario, incorporating knowledge from domain experts, relevant media, and external computation/simulation engines. The execution system and method execute scenarios created by the authoring system and method and provide a communication hub for the participation system and method. The participation system and method provide individuals, such as senior leaders and their staff, with appropriate views into the unfolding scenario and appropriate decisions to be made. The system and method also include features that allow for research and analysis with respect to, for example, efficient crisis response tactics.

Abstract: An authoring, execution, and participation software system and corresponding method for the capture and execution of real-world events (e.g., crises) involving individuals such as senior private and/or public sector leaders is presented. The authoring system and method are used to model a scenario, incorporating knowledge from domain experts, relevant media, and external computation/simulation engines. The execution system and method execute scenarios created by the authoring system and method and provide a communication hub for the participation system and method. The participation system and method provide individuals, such as senior leaders and their staff, with appropriate views into the unfolding scenario and appropriate decisions to be made. The system and method also include features that allow for research and analysis with respect to, for example, efficient crisis response tactics.

Abstract: The present invention is directed to a convertible apparel top such as a brassiere, tank top, or dress having two straps attached to the garment on at least one end of the strap with a swivel mechanism such as a means for attaching so that the garment may be converted from a garment with straps to a strapless garment and vice versa. In one embodiment, the ends of the straps not attached with a swivel mechanism may be removeably attached to the garment to facilitate the conversion, and may be configured to attach both to the garment and to each other for multiple looks and configurations such as strapless, parallel straps, crisscross straps, and a halter without the risk of losing the straps.

Abstract: An authoring, execution, and participation software system and corresponding method for the capture and execution of real-world events (e.g., crises) involving individuals such as senior private and/or public sector leaders is presented. The authoring system and method are used to model a scenario, incorporating knowledge from domain experts, relevant media, and external computation/simulation engines. The execution system and method execute scenarios created by the authoring system and method and provide a communication hub for the participation system and method. The participation system and method provide individuals, such as senior leaders and their staff, with appropriate views into the unfolding scenario and appropriate decisions to be made. The system and method also include features that allow for research and analysis with respect to, for example, efficient crisis response tactics.

Abstract: An authoring, execution, and participation software system and corresponding method for the capture and execution of real-world events (e.g., crises) involving individuals such as senior private and/or public sector leaders is presented. The authoring system and method are used to model a scenario, incorporating knowledge from domain experts, relevant media, and external computation/simulation engines. The execution system and method execute scenarios created by the authoring system and method and provide a communication hub for the participation system and method. The participation system and method provide individuals, such as senior leaders and their staff, with appropriate views into the unfolding scenario and appropriate decisions to be made. The system and method also include features that allow for research and analysis with respect to, for example, efficient crisis response tactics.