Patents by Inventor Adrian Edward Smith

Adrian Edward Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240024229
    Abstract: Compositions, methods and systems are provided for pulmonary or nasal delivery of two or more active agents via a metered dose inhaler. In one embodiment, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
    Type: Application
    Filed: March 23, 2023
    Publication date: January 25, 2024
    Inventors: Reinhard Vehring, Michael Steven Hartman, David Lechuga-Ballesteros, Adrian Edward Smith, Vidya B. Joshi, Sarvajna Kumar Dwivedi
  • Patent number: 11679384
    Abstract: Embodiments are directed towards methods and systems of depositing a uniform test-pathogen mixture onto a test article for testing the sterilization efficacy of an electromagnetic radiation or other sterilization process. The system includes a holding mechanism configured to removably secure the test article to the system. The system also includes a test-pathogen dispenser configured to uniformly deposit the test-pathogen mixture onto a reference surface of the test article. The system is structured so that at least one of the test article and the test-pathogen dispenser moves relative to the other. A plurality of test-pathogen mixture droplets or lines is deposited onto the reference surface in a predetermined test-pathogen pattern, such as, for example, a plurality of rows and columns of droplets. A distance from a dispenser tip of the test-pathogen dispenser to the reference surface of the test article may be determined to help maintain consistency between test-pathogen mixture droplets or lines.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: June 20, 2023
    Assignee: GERMITEC
    Inventor: Adrian Edward Smith
  • Patent number: 11660360
    Abstract: The invention concerns a disinfection device includes a disinfection chamber having an interior volume and a radiation source coupled to the interior volume. The radiation source is arranged to emit disinfecting radiation into the interior volume when in operation. A disinfection program in the disinfection chamber is arranged to control the radiation source to emit the disinfecting radiation according to parameters determined based on at least one of a three dimensional model of the disinfection chamber and a three dimensional model of a target article to be disinfected. The three dimensional model of the disinfection chamber is formed using data collected by operating at least one radiation source in a data collection disinfection chamber, or by providing a disinfection chamber model having a virtual interior volume. The three dimensional model of the target article to be disinfected is formed by providing a target article model having a virtual surface.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: May 30, 2023
    Assignee: GERMITEC
    Inventors: René Deshays, Clément Deshays, Cédric Neveu, Adrian Edward Smith, Frédéric Lepine
  • Publication number: 20220031894
    Abstract: The invention concerns a disinfection device includes a disinfection chamber having an interior volume and a radiation source coupled to the interior volume. The radiation source is arranged to emit disinfecting radiation into the interior volume when in operation. A disinfection program in the disinfection chamber is arranged to control the radiation source to emit the disinfecting radiation according to parameters determined based on at least one of a three dimensional model of the disinfection chamber and a three dimensional model of a target article to be disinfected. The three dimensional model of the disinfection chamber is formed using data collected by operating at least one radiation source in a data collection disinfection chamber, or by providing a disinfection chamber model having a virtual interior volume. The three dimensional model of the target article to be disinfected is formed by providing a target article model having a virtual surface.
    Type: Application
    Filed: December 5, 2019
    Publication date: February 3, 2022
    Inventors: René DESHAYS, Clément DESHAYS, Cédric NEVEU, Adrian Edward SMITH, Frédéric LEPINE
  • Publication number: 20210267881
    Abstract: Compositions, methods and systems are provided for pulmonary or nasal delivery of two or more active agents via a metered dose inhaler. In one embodiment, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
    Type: Application
    Filed: January 5, 2021
    Publication date: September 2, 2021
    Inventors: Reinhard Vehring, Michael Steven Hartman, David Lechuga-Ballesteros, Adrian Edward Smith, Vidya B. Joshi, Sarvajna Kumar Dwivedi
  • Publication number: 20210186861
    Abstract: Compositions, methods and systems are provided for pulmonary or nasal delivery of active agents via a metered dose inhaler. In one embodiment, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
    Type: Application
    Filed: August 3, 2020
    Publication date: June 24, 2021
    Inventors: Reinhard Vehring, Michael Steven Hartman, Adrian Edward Smith, Vidya B. Joshi, Sarvajna Kumar Dwivedi
  • Patent number: 10716753
    Abstract: Compositions, methods and systems are provided for pulmonary delivery of long-acting muscarinic antagonists and long-acting ?2 adrenergic receptor agonists via a metered dose inhaler. In particular embodiments, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: July 21, 2020
    Assignee: Pearl Therapeutics, Inc.
    Inventors: Reinhard Vehring, Michael Steven Hartman, Adrian Edward Smith, Vidya B. Joshi, Sarvajna Kumar Dwivedi
  • Publication number: 20200179543
    Abstract: The invention concerns a disinfection device includes a disinfection chamber having an interior volume and a radiation source coupled to the interior volume. The radiation source is arranged to emit disinfecting radiation into the interior volume when in operation. A disinfection program in the disinfection chamber is arranged to control the radiation source to emit the disinfecting radiation according to parameters determined based on at least one of a three dimensional model of the disinfection chamber and a three dimensional model of a target article to be disinfected. The three dimensional model of the disinfection chamber is formed using data collected by operating at least one radiation source in a data collection disinfection chamber, or by providing a disinfection chamber model having a virtual interior volume. The three dimensional model of the target article to be disinfected is formed by providing a target article model having a virtual surface.
    Type: Application
    Filed: December 6, 2019
    Publication date: June 11, 2020
    Inventors: René DESHAYS, Clément DESHAYS, Cédric NEVEU, Adrian Edward SMITH, Frédéric LEPINE
  • Publication number: 20200164358
    Abstract: Embodiments are directed towards methods and systems of depositing a uniform test-pathogen mixture onto a test article for testing the sterilization efficacy of an electromagnetic radiation or other sterilization process. The system includes a holding mechanism configured to removably secure the test article to the system. The system also includes a test-pathogen dispenser configured to uniformly deposit the test-pathogen mixture onto a reference surface of the test article. The system is structured so that at least one of the test article and the test-pathogen dispenser moves relative to the other. A plurality of test-pathogen mixture droplets or lines is deposited onto the reference surface in a predetermined test-pathogen pattern, such as, for example, a plurality of rows and columns of droplets. A distance from a dispenser tip of the test-pathogen dispenser to the reference surface of the test article may be determined to help maintain consistency between test-pathogen mixture droplets or lines.
    Type: Application
    Filed: July 21, 2017
    Publication date: May 28, 2020
    Inventor: Adrian Edward SMITH
  • Publication number: 20190358150
    Abstract: Compositions, methods and systems are provided for pulmonary or nasal delivery of two or more active agents via a metered dose inhaler. In one embodiment, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
    Type: Application
    Filed: December 20, 2018
    Publication date: November 28, 2019
    Inventors: Reinhard Vehring, Michael Steven Hartman, David Lechuga-Ballesteros, Adrian Edward Smith, Vidya B. Joshi, Sarvajna Kumar Dwivedi
  • Publication number: 20190307676
    Abstract: Compositions, methods and systems are provided for pulmonary delivery of long-acting muscarinic antagonists and long-acting ?2 adrenergic receptor agonists via a metered dose inhaler. In particular embodiments, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
    Type: Application
    Filed: November 2, 2018
    Publication date: October 10, 2019
    Inventors: Reinhard Vehring, Michael Steven Hartman, Adrian Edward Smith, Vidya B. Joshi, Sarvajna Kumar Dwivedi
  • Publication number: 20190038548
    Abstract: Compositions, methods and systems are provided for pulmonary or nasal delivery of active agents via a metered dose inhaler. In one embodiment, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
    Type: Application
    Filed: February 16, 2018
    Publication date: February 7, 2019
    Inventors: Reinhard Vehring, Michael Steven Hartman, Adrian Edward Smith, Vidya B. Joshi, Sarvajna Kumar Dwivedi
  • Patent number: 10111976
    Abstract: A disinfection device includes a disinfection chamber into which a radiation source emits ultraviolet-C (UV-C) radiation. A radiation sensor detects the amount of UV-C radiation within the disinfection chamber, and a temperature sensor produces temperature values of a temperature within the disinfection chamber. A processing unit generates accumulated UV-C radiation values and verifies that the accumulated UV-C radiation value in the disinfection chamber reaches a first radiation threshold while also verifying that the temperature in the disinfection chamber stays below a first temperature threshold. The UV-C radiation may be emitted into the disinfection chamber over one or more fixed periods of time while the total time for the disinfection process is limited to a primary time interval. The process may terminate successfully if the first radiation threshold is exceeded before the primary time interval expires.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: October 30, 2018
    Assignee: Germitec SA
    Inventors: Clément Deshays, Adrian Edward Smith, Robert Bruce Chess, Frédéric Lepine
  • Publication number: 20180125776
    Abstract: Compositions, methods and systems are provided for pulmonary delivery of long-acting muscarinic antagonists and long-acting ?2 adrenergic receptor agonists via a metered dose inhaler. In particular embodiments, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
    Type: Application
    Filed: June 15, 2017
    Publication date: May 10, 2018
    Inventors: Reinhard Vehring, Michael Steven Hartman, Adrian Edward Smith, Vidya B. Joshi, Sarvajna Kumar Dwivedi
  • Publication number: 20170112759
    Abstract: Compositions, methods and systems are provided for pulmonary delivery of long-acting muscarinic antagonists and long-acting ?2 adrenergic receptor agonists via a metered dose inhaler. In particular embodiments, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
    Type: Application
    Filed: August 30, 2016
    Publication date: April 27, 2017
    Inventors: Reinhard Vehring, Michael Steven Hartman, Adrian Edward Smith, Vidya B. Joshi, Sarvajna Kumar Dwivedi
  • Publication number: 20170071850
    Abstract: Compositions, methods and systems are provided for pulmonary or nasal delivery of active agents via a metered dose inhaler. In one embodiment, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
    Type: Application
    Filed: April 21, 2016
    Publication date: March 16, 2017
    Inventors: Reinhard Vehring, Michael Steven Hartman, Adrian Edward Smith, Vidya B. Joshi, Sarvajna Kumar Dwivedi
  • Publication number: 20170000725
    Abstract: Compositions, methods and systems are provided for pulmonary or nasal delivery of two or more active agents via a metered dose inhaler. In one embodiment, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
    Type: Application
    Filed: May 10, 2016
    Publication date: January 5, 2017
    Inventors: Reinhard Vehring, Michael Steven Hartman, David Lechuga-Ballesteros, Adrian Edward Smith, Vidya B. Joshi, Sarvajna Kumar Dwivedi
  • Patent number: 9463161
    Abstract: Compositions, methods and systems are provided for pulmonary delivery of long-acting muscarinic antagonists and long-acting ?2 adrenergic receptor agonists via a metered dose inhaler. In particular embodiments, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: October 11, 2016
    Assignee: Pearl Therapeutics, Inc.
    Inventors: Reinhard Vehring, Michael Steven Hartman, Adrian Edward Smith, Vidya B. Joshi, Sarvajna Kumar Dwivedi
  • Publication number: 20160279275
    Abstract: A disinfection device includes a disinfection chamber into which a radiation source emits ultraviolet-C (UV-C) radiation. A radiation sensor detects the amount of UV-C radiation within the disinfection chamber, and a temperature sensor produces temperature values of a temperature within the disinfection chamber. A processing unit generates accumulated UV-C radiation values and verifies that the accumulated UV-C radiation value in the disinfection chamber reaches a first radiation threshold while also verifying that the temperature in the disinfection chamber stays below a first temperature threshold. The UV-C radiation may be emitted into the disinfection chamber over one or more fixed periods of time while the total time for the disinfection process is limited to a primary time interval. The process may terminate successfully if the first radiation threshold is exceeded before the primary time interval expires.
    Type: Application
    Filed: June 2, 2016
    Publication date: September 29, 2016
    Inventors: Clément Deshays, Adrian Edward Smith, Robert Bruce Chess, Frédéric Lepine
  • Patent number: 9415009
    Abstract: Compositions, methods and systems are provided for pulmonary or nasal delivery of two or more active agents via a metered dose inhaler. In one embodiment, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: August 16, 2016
    Assignee: Pearl Therapeutics, Inc.
    Inventors: Reinhard Vehring, Michael Steven Hartman, David Lechuga-Ballesteros, Adrian Edward Smith, Vidya B. Joshi, Sarvajna Kumar Dwivedi