Abstract: The present disclosure provides peptides that modulate an immune response in an individual. The present disclosure provides peptides that modulate cellular responses in vitro. The present disclosure provides compositions comprising the peptides. The peptides and compositions are useful in methods of modulating an immune response in an individual, which methods are also provided.

Abstract: A system for displaying an image includes at least one x-ray source for emitting radiation, a detector for acquiring the radiation emitted by the radiation source for generating an x-ray image, the detector being disposed opposite the radiation source in relation to an object to be examined, a computer unit for performing computational operations, a display device for displaying x-ray images acquired by the detector and at least one data acquisition unit for acquiring surface information of the object to be examined. The data acquisition unit is disposed on the detector side and the computer unit is configured to correlate the data acquired by the detector-side data acquisition unit with the x-ray image.

Abstract: A bone fracture is treated by employing a database with comparison data records. The records each include at least one 3D image data record of at least one bone. Each comparison data record is assigned to an examination object, into which a comparison implant was implanted prior to recording the 3D image data record. A two-dimensional x-ray image of a target bone is generated. A 2D/3D registration of the x-ray image with 3D image data records is effected and a deviation value is calculated for each comparison data record. A reference data record is determined by selecting the comparison data record that includes the 3D image data record with the lowest deviation value. An implantation parameter is determined which describes a parameter of the implant and/or of a fastening element for fastening the implant, using the reference data record and/or displaying data of the reference data record on a display.

Abstract: A system for displaying an image includes at least one x-ray source for emitting radiation, a detector for acquiring the radiation emitted by the radiation source for generating an x-ray image, the detector being disposed opposite the radiation source in relation to an object to be examined, a computer unit for performing computational operations, a display device for displaying x-ray images acquired by the detector and at least one data acquisition unit for acquiring surface information of the object to be examined. The data acquisition unit is disposed on the detector side and the computer unit is configured to correlate the data acquired by the detector-side data acquisition unit with the x-ray image.

Abstract: A method for determining a distance between a first point and a second point on an object under examination inside the body of a person under examination by way of x-ray imaging by an x-ray device. The method includes the recording of x-ray images at different relative positionings of the x-ray device, which contain the first and the second point respectively. The relative positionings are substantially shifted in relation to one another in parallel to a central beam. Stereo reconstruction is carried out to define a 3D position of the first point and of the second point. The distance between the first point and the second point is determined from the 3D position of the first point and the 3D position of the second point.

Abstract: The present disclosure provides peptides that modulate an immune response in an individual. The present disclosure provides peptides that modulate cellular responses in vitro. The present disclosure provides compositions comprising the peptides. The peptides and compositions are useful in methods of modulating an immune response in an individual, which methods are also provided.

Abstract: A user is visually assisted when fixing an implant with a locking element in, or on, a bone. The location of a guide instrument for guiding the locking element relative to the implant is set by a target apparatus. The implant can be rotated and/or positioned by moving the target apparatus. The guide instrument carries at least one x-ray marker. An x-ray device records an x-ray image of the target region of the locking element and the x-ray marker. The orientation and position of a projected straight line, which forms a projection of a longitudinal axis of the guide instrument in the image plane, is determined from the position and/or form of the image of the x-ray marker. A superposed illustration is calculated of the x-ray image with a graphical element indicating the orientation and position of the projected straight line and the superposed illustration is output on a display.

Abstract: A bone fracture is treated by employing a database with comparison data records. The records each include at least one 3D image data record of at least one bone. Each comparison data record is assigned to an examination object, into which a comparison implant was implanted prior to recording the 3D image data record. A two-dimensional x-ray image of a target bone is generated. A 2D/3D registration of the x-ray image with 3D image data records is effected and a deviation value is calculated for each comparison data record. A reference data record is determined by selecting the comparison data record that includes the 3D image data record with the lowest deviation value. An implantation parameter is determined which describes a parameter of the implant and/or of a fastening element for fastening the implant, using the reference data record and/or displaying data of the reference data record on a display.

Abstract: A method for determining a distance between a first point and a second point on an object under examination inside the body of a person under examination by way of x-ray imaging by an x-ray device. The method includes the recording of x-ray images at different relative positionings of the x-ray device, which contain the first and the second point respectively. The relative positionings are substantially shifted in relation to one another in parallel to a central beam. Stereo reconstruction is carried out to define a 3D position of the first point and of the second point. The distance between the first point and the second point is determined from the 3D position of the first point and the 3D position of the second point.