Patents by Inventor Adrian Gilbert

Adrian Gilbert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150031774
    Abstract: This invention provides a solid pharmaceutical composition comprising rasagiline or a pharmaceutically acceptable salt of rasagiline, and particles having a non-filamentous microstructure of at least two sugar alcohols. This invention also provides a solid pharmaceutical composition comprising rasagiline or a pharmaceutically acceptable salt of rasagiline, a mixture of a disintegrant, a flow agent and particles having a non-filamentous microstructure of at least two sugar alcohols, a supplemental sugar alcohol, a supplemental flow agent, and a supplemental disintegrant. This invention further provides a method of treating a subject afflicted with Parkinson's disease comprising administering to the subject a therapeutically effective amount of the solid pharmaceutical composition, thereby treating the subject. Finally, this invention provides a process of making such solid pharmaceutical compositions.
    Type: Application
    Filed: August 13, 2014
    Publication date: January 29, 2015
    Applicant: TEVA PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Shulamit Patashnik, Daniella Licht, Adrian Gilbert
  • Patent number: 8383645
    Abstract: The invention relates to a pharmaceutical composition comprising a pharmaceutically acceptable salt of N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, N-methylglucamine, and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: August 7, 2012
    Date of Patent: February 26, 2013
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Shulamit Patashnik, Daniella Licht, Adrian Gilbert
  • Publication number: 20130023485
    Abstract: The subject invention provides a pharmaceutical composition comprising: an aqueous carrier; from 0.1 mg/ml to 20 mg/ml of a pharmaceutically acceptable salt of a) a peptide comprising at least 12 and at most 30 consecutive amino acids, b) a peptide comprising consecutive amino acids having the sequence shown by any of SEQ ID NOS. 8-17, c) a peptide comprising consecutive amino acids having a sequence of any of a) and b), or at least two sequences in (a), or d) a peptide comprising consecutive amino acids having a sequence comprising at least two identical sequences included in (a); and a solubility enhancer; and wherein the composition has a pH between 4 and 9, and a method of alleviating symptoms of SLE in a human by administering an effective amount of the composition.
    Type: Application
    Filed: April 23, 2012
    Publication date: January 24, 2013
    Inventors: Sharon Cohen-Vered, Esmira Naftali, Vera Weinstein, Adrian Gilbert, Ety Klinger
  • Publication number: 20120302600
    Abstract: The invention relates to a pharmaceutical composition comprising a pharmaceutically acceptable salt of N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, N-methylglucamine, and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: August 7, 2012
    Publication date: November 29, 2012
    Inventors: Shulamit Patashnik, Daniella Licht, Adrian Gilbert
  • Publication number: 20120238636
    Abstract: This invention provides a solid pharmaceutical composition comprising rasagiline or a pharmaceutically acceptable salt of rasagiline, and particles having a non-filamentous microstructure of at least two sugar alcohols. This invention also provides a solid pharmaceutical composition comprising rasagiline or a pharmaceutically acceptable salt of rasagiline, a mixture of a disintegrant, a flow agent and particles having a non-filamentous microstructure of at least two sugar alcohols, a supplemental sugar alcohol, a supplemental flow agent, and a supplemental disintegrant. This invention further provides a method of treating a subject afflicted with Parkinson's disease comprising administering to the subject a therapeutically effective amount of the solid pharmaceutical composition, thereby treating the subject. Finally, this invention provides a process of making such solid pharmaceutical compositions.
    Type: Application
    Filed: October 21, 2011
    Publication date: September 20, 2012
    Inventors: Shulamit Patashnik, Daniella Licht, Adrian Gilbert
  • Publication number: 20110301234
    Abstract: The invention relates to a pharmaceutical composition of R(+)-6-(N-methyl,N-ethyl-carbamoyloxy)-N?-propargyl-1-aminoindan ½ tartrate, at least one pharmaceutically acceptable excipient and up to 5% by weight of the composition of water. The composition is typically in a solid oral form which upon administration to a human subject provides a maximum blood plasma concentration of R(+)-6-(N-methyl,N-ethyl-carbamoyloxy)-N?-propargyl-1-aminoindan of at least 0.7 nmol/mL.
    Type: Application
    Filed: August 17, 2011
    Publication date: December 8, 2011
    Inventors: Daniella Licht, Ioana Lovinger, Fanny Caciularu, Adrian Gilbert
  • Publication number: 20110251235
    Abstract: The invention relates to a pharmaceutical composition comprising a pharmaceutically acceptable salt of N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, N-methylglucamine, and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: June 22, 2011
    Publication date: October 13, 2011
    Inventors: Shulamit Patashnik, Daniella Licht, Adrian Gilbert
  • Patent number: 8022104
    Abstract: Disclosed are formulations of ladostigil tartrate, including pharmaceutical compositions, process for the manufacture, and use thereof.
    Type: Grant
    Filed: February 24, 2006
    Date of Patent: September 20, 2011
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem, Technion Research and Development Foundation Ltd.
    Inventors: Daniella Licht, Ioana Lovinger, Fanny Caciularu, Adrian Gilbert
  • Patent number: 7989473
    Abstract: The invention relates to a pharmaceutical composition comprising a pharmaceutically acceptable salt of N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, N-methylglucamine, and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: June 12, 2007
    Date of Patent: August 2, 2011
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Shulamit Patashnik, Daniella Licht, Adrian Gilbert
  • Publication number: 20090169559
    Abstract: The subject invention provides a pharmaceutical composition comprising: an aqueous carrier; from 0.1 mg/ml to 20 mg/ml of the composition of a pharmaceutically acceptable salt of a) a peptide comprising at least 12 and at most 30 consecutive amino acids having a sequence corresponding to (i) a sequence of amino acids found within a complementarity-determining region (CDR) of a heavy or a light chain of a human monoclonal anti-DNA 16/6 Id antibody, or (ii) a sequence of amino acids found within a complementarity-determining region (CDR) of a heavy or a light chain of a pathogenic anti-DNA monoclonal antibody that induces a systemic lupus erythematosus (SLE)-like disease response in mice, or b) a peptide comprising consecutive amino acids having the sequence shown by any of SEQ ID NOS.
    Type: Application
    Filed: November 10, 2008
    Publication date: July 2, 2009
    Inventors: Sharon Cohen-Vered, Esmira Naftali, Vera Weinstein, Adrian Gilbert, Ety Klinger
  • Publication number: 20090111892
    Abstract: This invention provides a solid pharmaceutical composition comprising rasagiline or a pharmaceutically acceptable salt of rasagiline, and particles having a non-filamentous microstructure of at least two sugar alcohols. This invention also provides a solid pharmaceutical composition comprising rasagiline or a pharmaceutically acceptable salt of rasagiline, a mixture of a disintegrant, a flow agent and particles having a non-filamentous microstructure of at least two sugar alcohols, a supplemental sugar alcohol, a supplemental flow agent, and a supplemental disintegrant. This invention further provides a method of treating a subject afflicted with Parkinson's disease comprising administering to the subject a therapeutically effective amount of the solid pharmaceutical composition, thereby treating the subject. Finally, this invention provides a process of making such solid pharmaceutical compositions.
    Type: Application
    Filed: November 17, 2005
    Publication date: April 30, 2009
    Inventors: Shulamit Patashnik, Daniella Licht, Adrian Gilbert
  • Publication number: 20080287366
    Abstract: The subject invention provides a pharmaceutical composition comprising an aqueous carrier; from 0.1 mg/ml to 20 mg/ml of the composition of a pharmaceutically acceptable salt of a peptide having the structural formula NH2-Gly Tyr Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys Gly Glu Glu Trp Ile Gly-COOH; and a substituted ?-cyclodextrin in an amount effective to dissolve the peptide in the aqueous carrier, wherein the composition has a pH between 4 and 9, a process for preparation, and a method of alleviating symptoms of systemic lupus erythematosus (SLE) in a human subject comprising administering to the human subject the pharmaceutical composition.
    Type: Application
    Filed: November 12, 2007
    Publication date: November 20, 2008
    Inventors: Sharon Cohen-Vered, Esmira Naftali, Vera Weinstein, Adrian Gilbert, Ety Klinger
  • Publication number: 20080107729
    Abstract: This invention provides a solid pharmaceutical composition comprising an active ingredient (e.g., rasagiline) or a pharmaceutically acceptable salt thereof, and particles having a non-filamentous microstructure of at least two sugar alcohols. This invention also provides a solid pharmaceutical composition comprising an active ingredient (e.g., rasagiline) or a pharmaceutically acceptable salt thereof, a mixture of a disintegrant, a flow agent and particles having a non-filamentous microstructure of at least two sugar alcohols, a supplemental sugar alcohol, a supplemental flow agent, and a supplemental disintegrant. Finally, this invention provides a process of making such solid pharmaceutical compositions.
    Type: Application
    Filed: May 23, 2007
    Publication date: May 8, 2008
    Inventors: Arun F. Amin, Sarath Chandar, Adrian Gilbert, Dannit Licht, Gary T. Norman, Shuli Patashnik
  • Publication number: 20070293537
    Abstract: The invention relates to a pharmaceutical composition comprising a pharmaceutically acceptable salt of N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, N-methylglucamine, and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: June 12, 2007
    Publication date: December 20, 2007
    Inventors: Shulamit Patashnik, Daniella Licht, Adrian Gilbert
  • Patent number: 7294687
    Abstract: The subject invention provides a pharmaceutical composition comprising an aqueous carrier; from 0.1 mg/ml to 20 mg/ml of the composition of a pharmaceutically acceptable salt of a peptide having the structural formula NH2-Gly Tyr Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys Gly Glu Glu Trp Ile Gly-COOH; and a substituted ?-cyclodextrin in an amount effective to dissolve the peptide in the aqueous carrier, wherein the composition has a pH between 4 and 9, a process for preparation, and a method of alleviating symptoms of systemic lupus erythematosus (SLE) in a human subject comprising administering to the human subject the pharmaceutical composition.
    Type: Grant
    Filed: January 14, 2004
    Date of Patent: November 13, 2007
    Assignee: TEVA Pharmaceutical Industries, Ltd.
    Inventors: Sharon Cohen-Vered, Esmira Naftali, Vera Weinstein, Adrian Gilbert, Ety Klinger
  • Publication number: 20060189685
    Abstract: Disclosed are formulations of ladostigil tartrate, including pharmaceutical compositions, process for the manufacture, and use thereof.
    Type: Application
    Filed: February 24, 2006
    Publication date: August 24, 2006
    Inventors: Daniella Licht, Ioana Lovinger, Fanny Caciularu, Adrian Gilbert
  • Publication number: 20060177004
    Abstract: A method and apparatus for monitoring network resources is disclosed. Code for use in instructing components in a network monitoring system is provided. The components include at least one data gathering for gathering operation data from a monitor network constituent. A main computer system has a database for storing the operation data. A data forwarder permits communication of the operation data from the data gather to the computer system. The computer system is remotely located from the data gatherer. The code includes information for creating custom tables in the database to hold the operation data. Information permits the data gatherer to selectively gather the operation data from other possible data that is capable of being gathered from the monitor constituent.
    Type: Application
    Filed: January 26, 2005
    Publication date: August 10, 2006
    Applicant: N-Able Technologies International, Inc.
    Inventor: Adrian Gilbert
  • Patent number: 7022663
    Abstract: Pharmaceutical compositions useful for treating autoimmune diseases in a mammal comprising as an active ingredient a therapeutically effective amount of Copolymer 1, and microcrystalline cellulose are disclosed. Processes for the manufacture of such compositions are also disclosed.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: April 4, 2006
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Adrian Gilbert, Rivka Riven-Kreitman, Milka Linenberg, Sharon Cohen-Vered, Ramon F. Joubran
  • Publication number: 20060018957
    Abstract: Provided are pharmaceutical dosage forms that include rasagiline formulated and fabricated so that release of rasagiline in the stomach is retarded or inhibited.
    Type: Application
    Filed: July 26, 2005
    Publication date: January 26, 2006
    Inventors: E. Lerner, Vered Rosenberger, Ofer Aqua, Moshe Flashner-Barak, Adrian Gilbert, Daniella Licht, Shulamit Patashnik
  • Publication number: 20050235058
    Abstract: A network monitoring architecture for multiple computer network systems is disclosed. In particular, the network monitoring architecture includes an agent system installed within each computer network and a remote central management unit in communication with the agent system of each computer network. The agent systems collect data from key network devices that reside on the corresponding computer network, and send the collected data to the remote central management unit as a message through the Internet. The data from the computer networks are processed at the remote central management unit to determine imminent or actual failure of the monitored network devices. The appropriate technicians can be immediately notified by the central management unit through automatically generated messages.
    Type: Application
    Filed: October 8, 2004
    Publication date: October 20, 2005
    Inventors: Phil Rackus, Claudiu Carter, Jean Fauteux, Adrian Gilbert