Abstract: A spring stop arrangement for a check valve may include: a check seat defining a flow path; a clapper assembly connected to the check seat and configured to obstruct the flow path, the clapper assembly including: a clapper; and a seal retainer detachably mounted to the clapper; a cam arm connected to the check seat, the cam arm including a stopper; and a torsion spring operatively connected to the cam arm so as to apply a biasing force to the cam arm against the direction of fluid flow. When the seal retainer is dismounted from the clapper, the stopper may be configured to contact the check seat so as to prevent rotation of the cam arm.

Abstract: A check valve may include: a check seat defining a flow path; a clapper assembly hingedly connected to the check seat and configured to obstruct the flow path, including: a clapper and a seal retainer detachably mounted to the clapper; a first extension extending from the clapper assembly in an upstream direction and having a roller; a cam arm rotatable relative to the clapper assembly and configured to engage with the roller; and a torsion spring operatively connected to the cam arm so as to apply a biasing force to the cam arm in the upstream direction. The biasing force may be imparted to the clapper assembly via the cam arm and roller, so that the clapper assembly obstructs the flow path.

Abstract: Therapeutics and methods of diagnosing non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) in a patient comprising obtaining a sample from the patient, determining a level of a signaling lymphocytic activation molecule 1 (SLAMF1) in the sample from the patient, and diagnosing the patient with NAFLD when the level of the SLAMF1 is at least an elevated threshold level for the SLAMF1. Therapeutics and methods of treating non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) in a patient in need of treatment comprising administering a pharmaceutically effective dose of a therapeutic, wherein the therapeutic includes a signaling lymphocytic activation molecule 1 (SLAMF1) antagonist.

Abstract: Disclosed herein are pyrazole pyrimidine compounds that modulate and/or inhibit hematopoietic progenitor kinase 1, as well as methods of making such compounds and therapeutic methods of using same.

Abstract: An attachment assembly for use with furniture and other articles. The attachment assembly includes a connector assembly that is configured to engage with a rail. The connector assembly includes a first, fixed protrusion, a lever, a second protrusion extending from the lever, and a third protrusion positioned between the first protrusion and the second protrusion. The rail includes a lip and a cutout in the lip that is sized to receive the third protrusion. The rail is configured to retain the connector assembly. Pivoting the lever when the connector assembly is positioned within the rail is configured to cause the second protrusion to bear against a bottom surface of the rail, such that the first protrusion and the second protrusion frictionally engage the bottom surface of the rail and the third protrusion frictionally engages the lip to fixedly hold the connector assembly.

Abstract: An assembly comprising a first furniture component and a second furniture component is disclosed. The first furniture component comprises a spring-loaded detent. The spring-loaded detent is biased axially along a central axis toward a locked configuration. The second furniture component comprises a lock arrangement. The first furniture component and the second furniture component are rotatably connected about the central axis through a rotary range of motion. The lock arrangement is configured to move the spring-loaded detent from the locked configuration to an unlocked configuration during the rotary range of motion, release the spring-loaded detent from the unlocked configuration after the rotary range of motion, and prevent rotation of the spring-loaded detent in the locked configuration after the rotary range of motion.

Abstract: An attachment assembly for use with furniture and other articles. The attachment assembly includes a connector assembly that is configured to engage with a rail. The connector assembly includes a first, fixed protrusion, a lever, a second protrusion extending from the lever, and a third protrusion positioned between the first protrusion and the second protrusion. The rail includes a lip and a cutout in the lip that is sized to receive the third protrusion. The rail is configured to retain the connector assembly. Pivoting the lever when the connector assembly is positioned within the rail is configured to cause the second protrusion to bear against a bottom surface of the rail, such that the first protrusion and the second protrusion frictionally engage the bottom surface of the rail and the third protrusion frictionally engages the lip to fixedly hold the connector assembly.

Abstract: Clamping arrangements for assembling components of modular furniture are disclosed. The clamping arrangements can include a frame comprising a cavity intermediate opposing sidewall surfaces. The clamping arrangements can also include a spring positioned in the cavity, wherein the spring comprises a folded metal sheet. The clamping arrangements can also include a lever comprising a camming surface, wherein the lever is pivotably coupled to the first sidewall and the second sidewall about an axis of rotation and pivotable between an unclamped position and a clamped position. The camming surface can be configured to directly engage the spring and deform the spring to a clamping configuration when the lever is in the clamped position.

Abstract: An attachment assembly for use with furniture and other articles. The attachment assembly includes a connector assembly that is configured to engage with a rail. The connector assembly includes a first, fixed protrusion, a lever, a second protrusion extending from the lever, and a third protrusion positioned between the first protrusion and the second protrusion. The rail includes a lip and a cutout in the lip that is sized to receive the third protrusion. The rail is configured to retain the connector assembly. Pivoting the lever when the connector assembly is positioned within the rail is configured to cause the second protrusion to bear against a bottom surface of the rail, such that the first protrusion and the second protrusion frictionally engage the bottom surface of the rail and the third protrusion frictionally engages the lip to fixedly hold the connector assembly.

Abstract: A multipurpose desk system assembly and an associated method of assembling the desk system are disclosed. The desk system assembly may include a top panel assembly and a base support system configured with clamping devices for convenient assembly. The desk system assembly may comprise multiple top panel assemblies and can be configured to be readily converted or customized to fit the needs of an end user.

Abstract: A power rail system including a rail assembly, which includes a sidewall, a first interior compartment at least partially enclosed by the sidewall, the first interior compartment extending longitudinally along the first rail assembly, an opening in communication with the first interior compartment, the opening positioned along the sidewall, and a second interior compartment at least partially enclosed by the sidewall, the second interior compartment extending longitudinally along the first rail assembly and configured to receive the connector member therein. The power rail system can further include an electrical outlet assembly positionable within the first interior compartment. Further, various accessories, such as privacy screens, can be supported by the rail assembly. Still further, multiple rail assemblies can be connected together to customize the size and/or configuration of the power rail system.

Abstract: A multipurpose desk system assembly and an associated method of assembling the desk system are disclosed. The desk system assembly may include a top panel assembly and a base support system configured with clamping devices for convenient assembly. The desk system assembly may comprise multiple top panel assemblies and can be configured to be readily converted or customized to fit the needs of an end user.

Abstract: A power rail system including a rail assembly, which includes a sidewall, a first interior compartment at least partially enclosed by the sidewall, the first interior compartment extending longitudinally along the first rail assembly, an opening in communication with the first interior compartment, the opening positioned along the sidewall, and a second interior compartment at least partially enclosed by the sidewall, the second interior compartment extending longitudinally along the first rail assembly and configured to receive the connector member therein. The power rail system can further include an electrical outlet assembly positionable within the first interior compartment. Further, various accessories, such as privacy screens, can be supported by the rail assembly. Still further, multiple rail assemblies can be connected together to customize the size and/or configuration of the power rail system.

Abstract: A power rail system including a rail assembly, which includes a sidewall, a first interior compartment at least partially enclosed by the sidewall, the first interior compartment extending longitudinally along the first rail assembly, an opening in communication with the first interior compartment, the opening positioned along the sidewall, and a second interior compartment at least partially enclosed by the sidewall, the second interior compartment extending longitudinally along the first rail assembly and configured to receive the connector member therein. The power rail system can further include an electrical outlet assembly positionable within the first interior compartment. Further, various accessories, such as privacy screens, can be supported by the rail assembly. Still further, multiple rail assemblies can be connected together to customize the size and/or configuration of the power rail system.