Patents by Inventor Adrian M Lowe

Adrian M Lowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for detecting microorganisms
    Patent number: 9017963
    Abstract: Described herein are methods of detecting a wound infection and for detecting the presence or absence of microorganisms, for example, wound pathogens in a sample, by contacting a sample with an enzyme produced and/or secreted by the bacteria, and detecting modification or the absence of modification of the substrate, as an indicator of the presence or absence of the enzyme in the sample. The present invention also features a biosensor for detecting the presence or absence of bacteria in a sample.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: April 28, 2015
    Assignee: Woundchek Laboratories (US), Inc.
    Inventors: Mitchell C. Sanders, Adrian M. Lowe, Maureen A. Hamilton, Gerard J. Colpas
  • METHOD FOR DETECTING MICROORGANISMS
    Publication number: 20140051089
    Abstract: Described herein are methods of detecting a wound infection and for detecting the presence or absence of microorganisms, for example, wound pathogens in a sample, by contacting a sample with an enzyme produced and/or secreted by the bacteria, and detecting modification or the absence of modification of the substrate, as an indicator of the presence or absence of the enzyme in the sample. The present invention also features a biosensor for detecting the presence or absence of bacteria in a sample.
    Type: Application
    Filed: July 23, 2013
    Publication date: February 20, 2014
    Applicant: Systagenix Wound Management (US), Inc.
    Inventors: Mitchell C. Sanders, Adrian M. Lowe, Maureen A. Hamilton, Gerard J. Colpas
  • ama
    Publication number: 20020052472
    Abstract: The invention provides ama polypeptides and polynucleotides encoding ama polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ama polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: January 12, 2001
    Publication date: May 2, 2002
    Inventors: David T. Beattie, Robert L. Deresiewicz, Adrian M. Lowe, Michael A. Lonetto, John E. Hodgson, Richard O. Nicholas, Leslie Marie Palmer, Julie M. Pratt
  • Ribosome recycling factor (FRR) of Staphylococcus aureus
    Patent number: 6238887
    Abstract: This invention provides frr polypeptides and polynucleotides encoding frr polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing frr polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: May 29, 2001
    Assignees: Brigham & Women's Hospital, Virus Research Institute, SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: David T Beattie, Robert L Deresiewicz, Adrian M Lowe, Michael A Lonetto, John E Hodgson, Richard O Nicholas, Leslie Marie Palmer, Julie M Pratt
  • UDP-N-acetylmuramoyl-l-alanine:D-glutamate ligase (MURD) of staphylococcus aureus
    Patent number: 6211161
    Abstract: The invention provides murD polypeptides and polynucleotides encoding murD polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing murD polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: April 3, 2001
    Assignees: Brigham & Women's Hospital, Virus Research Institute, SmithKline Beecham Corporation, SmithKline Beecham plc,
    Inventors: David T Beattie, Robert L Deresiewicz, Adrian M Lowe, Richard O Nicholas, Leslie Marie Palmer, Julie M Pratt, Michael A Lonetto, John E Hodgson
  • Ama
    Patent number: 6197549
    Abstract: This invention provides ama polypeptides and polynucleotides encoding ama polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ama polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: March 6, 2001
    Assignees: Brigham & Women's Hospital, Virus Research Institute, SmithKline Beecham Corporation, SmithKline Beecham, plc
    Inventors: Richard O Nicholas, Leslie Marie Palmer, Julie M Pratt, David T. Beattie, Robert L Deresiewicz, Adrian M Lowe, Michael A Lonetto, John E Hodgson
  • Staphylococcus aureus 3-hydroxyacyl-CoA dehydrogenase
    Patent number: 6146863
    Abstract: The invention provides hcd polypeptides and polynucleotides encoding Staphylococcus aureus 3-hydroxyacyl-CoA dehydrogenase (hcd) polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing hod polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: March 18, 1999
    Date of Patent: November 14, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventors: Leslie Marie Palmer, Michael A Lonetto, Richard O Nicholas, Robert L Deresiewicz, Julie M Pratt, John E Hodgson, David T Beattie, Adrian M Lowe
  • ClpL
    Patent number: 6126937
    Abstract: The invention provides clpL polypeptides, polynucleotides encoding clpL polypeptides and methods for producing such polypeptides by recombinant techniques.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: October 3, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc, Virus Research Institute, Brigham & Women's Hospital
    Inventors: David T Beattie, Robert L Deresiewicz, Adrian M Lowe, Michael A Lonetto, John E Hodgson, Richard O Nicholas, Leslie Marie Palmer, Julie M Pratt