Patents by Inventor Adrian M. Senderowicz

Adrian M. Senderowicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6660750
    Abstract: Disclosed is the unexpected discovery that flavopiridol binds tightly to the transcription elongation factor, P-TEFb and dramatically inhibits its activity. As P-TEFb is required for HIV propagation and replication, this invention provides new methods, compositions and kits for the effective treatment of HIV infections and AIDS using flavopiridol, both alone and combination with other therapies.
    Type: Grant
    Filed: February 15, 2001
    Date of Patent: December 9, 2003
    Assignees: University of Iowa Research Foundation, The United States of America as represented by the Department of Health and Human Services
    Inventors: David H. Price, Adrian M. Senderowicz
  • Publication number: 20010051635
    Abstract: Disclosed is the unexpected discovery that flavopiridol binds tightly to the transcription elongation factor, P-TEFb and dramatically inhibits its activity. As P-TEFb is required for HIV propagation and replication, this invention provides new methods, compositions and kits for the effective treatment of HIV infections and AIDS using flavopiridol, both alone and combination with other therapies.
    Type: Application
    Filed: February 15, 2001
    Publication date: December 13, 2001
    Inventors: David H. Price, Adrian M. Senderowicz