Patents by Inventor Adrian Philip Kells

Adrian Philip Kells has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AADC polynucleotides for the treatment of Parkinson's disease
    Patent number: 11975056
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: May 7, 2024
    Assignee: Voyager Therapeutics, Inc.
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • Trajectory array guide system
    Patent number: 11497576
    Abstract: The present disclosure presents a trajectory array guide system for defining a trajectory to a target location in the brain of a subject and for guiding an elongated tool along the trajectory. The trajectory array guide system can comprise: a base, an array guide, an imaging unit, and an elongated handle configured for connection with a stereotaxic navigation system. The present disclosure presents a method of using a trajectory array guide system for defining a trajectory to a target location in the brain of a subject and for guiding an elongated tool along the trajectory.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: November 15, 2022
    Assignees: Voyager Therapeutics, Inc., The Regents of the University of California
    Inventors: Adrian Philip Kells, Stefan Schreck, Edward H. Luttich, Kenneth A. Bloch, Krystof Bankiewicz
  • CANNULA SYSTEM AND USE THEREOF
    Publication number: 20210361318
    Abstract: The present disclosure relates to cannula systems for delivery of a therapeutic agent to parenchymal tissue of a target subject. In certain embodiments, the cannula system is for delivery of a therapeutic agent to parenchymal tissue in the spine of a target subject. In certain embodiments, the cannula system includes a cannula positioning guide (CPG) useful in the delivery of a therapeutic agent to a localized target tissue of a subject. The guide may be used in a surgical suite or during a surgical procedure.
    Type: Application
    Filed: July 2, 2019
    Publication date: November 25, 2021
    Inventors: Holger Patzke, Steven M. Hersch, Jenna Carroll Soper, Adrian Philip Kells, Nicholas Boulis, Donna T. Ward
  • AADC POLYNUCLEOTIDES FOR THE TREATMENT OF PARKINSON'S DISEASE
    Publication number: 20210338786
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Application
    Filed: May 3, 2021
    Publication date: November 4, 2021
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON'S DISEASE
    Publication number: 20210198691
    Abstract: The present disclosure relates to methods, formulations and devices for the delivery and therapeutic administration of polynucleotides encoding AADC. The present disclosure relates to methods, formulations and devices for the delivery and therapeutic administration of AAV vectors which include polynucleotides encoding AADC. The present disclosure relates to methods, formulations and devices for the delivery and therapeutic administration of polynucleotides encoding AADC in the treatment of neurological diseases, disorders and conditions, including Parkinson's Disease.
    Type: Application
    Filed: May 15, 2019
    Publication date: July 1, 2021
    Applicant: Voyager Therapeutics, Inc.
    Inventors: Bernard RAVINA, Adrian Philip KELLS
  • AADC polynucleotides for the treatment of Parkinson's disease
    Patent number: 11027000
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: June 8, 2021
    Assignee: Voyager Therapeutics, Inc.
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • TRAJECTORY ARRAY GUIDE SYSTEM
    Publication number: 20200229889
    Abstract: The present disclosure presents a trajectory array guide system for defining a trajectory to a target location in the brain of a subject and for guiding an elongated tool along the trajectory. The trajectory array guide system can comprise: a base, an array guide, an imaging unit, and an elongated handle configured for connection with a stereotaxic navigation system. The present disclosure presents a method of using a trajectory array guide system for defining a trajectory to a target location in the brain of a subject and for guiding an elongated tool along the trajectory.
    Type: Application
    Filed: July 17, 2018
    Publication date: July 23, 2020
    Inventors: Adrian Philip Kells, Stefan Schreck, Edward H. Luttich, Kenneth A. Bloch, Krystof Bankiewicz
  • CENTRAL NERVOUS SYSTEM TARGETING POLYNUCLEOTIDES
    Publication number: 20190365793
    Abstract: The present disclosure relates to compositions, methods and processes for the formulation and for the administration of a gene therapy agent using parvovirus e.g., adeno-associated virus (AAV) to the CNS, CNS tissues, CNS structures or CNS cells.
    Type: Application
    Filed: June 14, 2019
    Publication date: December 5, 2019
    Inventors: Gregory Robert Stewart, Dinah Wen-Yee Sah, Jinzhao Hou, Adrian Philip Kells, Martin Goulet, Kartik Ramamoorthi, Pengcheng Zhou, Yanqun Shu
  • AADC POLYNUCLEOTIDES FOR THE TREATMENT OF PARKINSON'S DISEASE
    Publication number: 20190358306
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Application
    Filed: August 14, 2019
    Publication date: November 28, 2019
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • AADC polynucleotides for the treatment of parkinson's disease
    Patent number: 10335466
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: July 2, 2019
    Assignee: VOYAGER THERAPEUTICS, INC.
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF AADC DEFICIENCY
    Publication number: 20190054158
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment, prophylaxis, palliation or amelioration of diseases, conditions and/or symptoms resulting from AADC deficiency and related inborn errors of neurotransmitter metabolism.
    Type: Application
    Filed: November 2, 2018
    Publication date: February 21, 2019
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • DELIVERY OF CENTRAL NERVOUS SYSTEM TARGETING POLYNUCLEOTIDES
    Publication number: 20190055578
    Abstract: The invention relates to compositions and methods for the preparation, administration, manufacture and therapeutic use of viral particles for the treatment of CNS disorders.
    Type: Application
    Filed: October 28, 2016
    Publication date: February 21, 2019
    Applicant: Voyager Therapeutics, Inc.
    Inventors: Dinah Wen-Yee SAH, Jinzhao HOU, Martin GOULET, Adrian Philip KELLS, Pengcheng ZHOU, Gregory Robert STEWART
  • AADC POLYNUCLEOTIDES FOR THE TREATMENT OF PARKINSON'S DISEASE
    Publication number: 20190008932
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Application
    Filed: September 20, 2018
    Publication date: January 10, 2019
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • AADC POLYNUCLEOTIDES FOR THE TREATMENT OF PARKINSON'S DISEASE
    Publication number: 20190008931
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Application
    Filed: September 20, 2018
    Publication date: January 10, 2019
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • AADC POLYNUCLEOTIDES FOR THE TREATMENT OF PARKINSON'S DISEASE
    Publication number: 20190008933
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Application
    Filed: September 20, 2018
    Publication date: January 10, 2019
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF AADC DEFICIENCY
    Publication number: 20190000940
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment, prophylaxis, palliation or amelioration of diseases, conditions and/or symptoms resulting from AADC deficiency and related inborn errors of neurotransmitter metabolism.
    Type: Application
    Filed: July 29, 2016
    Publication date: January 3, 2019
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • CENTRAL NERVOUS SYSTEM TARGETING POLYNUCLEOTIDES
    Publication number: 20180021364
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding payloads for the treatment of CNS disorders.
    Type: Application
    Filed: January 15, 2016
    Publication date: January 25, 2018
    Inventors: Gregory Robert Stewart, Dinah Wen-Yee Sah, Jinzhao Hou, Adrian Philip Kells, Martin Goulet, Kartik Ramamoorthi, Pengcheng Zhou, Yanqun Shu
  • AADC POLYNUCLEOTIDES FOR THE TREATMENT OF PARKINSON'S DISEASE
    Publication number: 20170333538
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Application
    Filed: November 5, 2015
    Publication date: November 23, 2017
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina