Patents by Inventor Adrian Prokop
Adrian Prokop has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20070265560Abstract: In one embodiment of the present invention, a system for treating an occlusion within a patient's vasculature with ultrasonic energy comprises a catheter configured to be passed through the patient's vasculature such that a portion of the catheter is positioned at an intravascular treatment site. The system further comprises an ultrasound radiating member, an ultrasound signal generator configured to supply a drive signal to the ultrasound radiating member, an infusion pump configured to pump a therapeutic compound into the fluid delivery lumen so as to cause the therapeutic compound to be delivered to the treatment site and a controller configured to control the ultrasound signal generator and the infusion pump.Type: ApplicationFiled: April 24, 2007Publication date: November 15, 2007Applicant: EKOS CORPORATIONInventors: Azita Soltani, Adrian Prokop
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Publication number: 20060184074Abstract: The present invention employs hydrogels as acoustic couplings for clinical applications of ultrasound imaging and therapy, but is particularly applicable to high intensity focused ultrasound (HIFU) based therapy. While other materials can be used, it has been determined that polyacrylamide is sufficiently robust and transmissive to withstand the high temperatures encountered in HIFU therapy. One embodiment of a hydrogel coupling is configured in shape and size (length) to ensure that a focal region of an ultrasound transducer is disposed proximate the target area when the distal tip of the transducer is in contact with tissue. These couplings can be shaped to correspond to the beam focus characteristics of specific transducers. Water can be applied to hydrate the tip of the hydrogel coupling during use, and medication absorbed into the hydrogel material can be applied to the tissue in contact with the distal surface of the hydrogel.Type: ApplicationFiled: March 7, 2006Publication date: August 17, 2006Applicant: University of WashingtonInventors: Shahram Vaezy, Adrian Prokop, Roy Martin, Peter Kaczkowski, Misty Noble
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Patent number: 7070565Abstract: The present invention employs hydrogels as acoustic couplings for clinical applications of ultrasound imaging and therapy, but is particularly applicable to high intensity focused ultrasound (HIFU) based therapy. While other materials can be used, it has been determined that polyacrylamide is sufficiently robust and transmissive to withstand the high temperatures encountered in HIFU therapy. One embodiment of a hydrogel coupling is configured in shape and size (length) to ensure that a focal region of an ultrasound transducer is disposed proximate the target area when the distal tip of the transducer is in contact with tissue. These couplings can be shaped to correspond to the beam focus characteristics of specific transducers. Water can be applied to hydrate the tip of the hydrogel coupling during use, and medication absorbed into the hydrogel material can be applied to the tissue in contact with the distal surface of the hydrogel.Type: GrantFiled: May 30, 2003Date of Patent: July 4, 2006Assignee: University of WashingtonInventors: Shahram Vaezy, Adrian Prokop, Roy W. Martin, Peter Kaczkowski, Misty Noble
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Patent number: 6880242Abstract: A circuit protection device for protection of sensitive components during high energy radiation sterilization that includes a support substrate and a protective housing. The substrate supports the sensitive components. The protective housing is hermetically coupled to the support substrate to seal the sensitive components within the protective housing. Preferably, the protective housing stops high energy used in the high energy sterilization from damaging the sensitive components from a predetermined exposure level of high energy sterilization. The circuit protection device may further include a protective conductor that is coupled to the support substrate on a side which is opposite the protective housing to prevent high energy from entering the opposite side of the support substrate.Type: GrantFiled: March 6, 2003Date of Patent: April 19, 2005Assignee: MiniMed Inc.Inventors: William P. Van Antwerp, Sheana Karre, Adrian Prokop, Sara Akiko Stinson, Jason Fong, James J. Rosenberg
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Publication number: 20030233045Abstract: The present invention employs hydrogels as acoustic couplings for clinical applications of ultrasound imaging and therapy, but is particularly applicable to high intensity focused ultrasound (HIFU) based therapy. While other materials can be used, it has been determined that polyacrylamide is sufficiently robust and transmissive to withstand the high temperatures encountered in HIFU therapy. One embodiment of a hydrogel coupling is configured in shape and size (length) to ensure that a focal region of an ultrasound transducer is disposed proximate the target area when the distal tip of the transducer is in contact with tissue. These couplings can be shaped to correspond to the beam focus characteristics of specific transducers. Water can be applied to hydrate the tip of the hydrogel coupling during use, and medication absorbed into the hydrogel material can be applied to the tissue in contact with the distal surface of the hydrogel.Type: ApplicationFiled: May 30, 2003Publication date: December 18, 2003Applicant: University of WashingtonInventors: Shahram Vaezy, Adrian Prokop, Roy W. Martin, Peter Kaczkowski, Misty Noble
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Publication number: 20030169582Abstract: A circuit protection device for protection of sensitive components during high energy radiation sterilization that includes a support substrate and a protective housing. The substrate supports the sensitive components. The protective housing is hermetically coupled to the support substrate to seal the sensitive components within the protective housing. Preferably, the protective housing stops high energy used in the high energy sterilization from damaging the sensitive components from a predetermined exposure level of high energy sterilization. The circuit protection device may further include a protective conductor that is coupled to the support substrate on a side which is opposite the protective housing to prevent high energy from entering the opposite side of the support substrate.Type: ApplicationFiled: March 6, 2003Publication date: September 11, 2003Inventors: William P. Van Antwerp, Sheana Karre, Adrian Prokop, Sara Akiko Stinson, Jason Fong, James J. Rosenberg
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Patent number: 6594156Abstract: A circuit protection device for protection of sensitive components during high energy radiation sterilization that includes a support substrate and a protective housing. The substrate supports the sensitive components. The protective housing is hermetically coupled to the support substrate to seal the sensitive components within the protective housing. Preferably, the protective housing stops high energy used in the high energy sterilization from damaging the sensitive components from a predetermined exposure level of high energy sterilization. The circuit protection device may further include a protective conductor that is coupled to the support substrate on a side which is opposite the protective housing to prevent high energy from entering the opposite side of the support substrate.Type: GrantFiled: April 24, 2000Date of Patent: July 15, 2003Assignee: MiniMed Inc.Inventors: William P. Van Antwerp, Sheana Karre, Adrian Prokop, Sara Akiko Stinson, Jason Fong, James J. Rosenberg
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Patent number: 6519485Abstract: A system for assessing organ function couples light emitters into an optical fiber delivery assembly of which the tip extends to or into an internal organ and illuminates tissue; the device senses temperature at the tip, and a collection fiber collects light scattered, reflected or emitted by the surrounding tissue. Control and processing modules drive the laser diodes and process return spectral signals, e.g., to assess metabolic activity and detect onset of shock. A prototype uses four laser diodes with peaks at 735, 760, 805 and 890 nm, with a front end splitter providing a reference beam to a photo detector for normalizing detection output and correcting the signal samples. The device may include a plurality of laser diodes and may select subsets of the sources to tailor spectral illumination to different target enzymes, metabolites or other compounds.Type: GrantFiled: December 13, 2000Date of Patent: February 11, 2003Assignee: The General Hospital CorporationInventors: William P. Wiesmann, Adrian Richard Urias, Jill Uyeno, Adrian Prokop, Jason Milne, Kristopher Jarka, Farbod Ghassemi
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Publication number: 20020072661Abstract: A system for assessing organ function has a plurality of light emitters of distinct spectral characteristics are coupled into a percutaneous fiber delivery assembly with a tip extending to or into an internal organ to illuminate organ tissue. The assembly includes a delivery optical fiber, and a collection fiber that collects and returns light scattered, reflected or emitted by the surrounding tissue to a detector at the proximal end. The device also senses temperature at the tip. Control and processing modules drive the laser diodes and process the return signals. The instrument may assess general metabolic activity by detecting light absorption of a linked substance, for example at a peak attributed to deoxygenated hemoglobin and/or at one or more peaks attributed to oxygenated hemoglobin. Preferably, change of a parameter such as pulse oxygen saturation together with one or more other parameters such as temperature are detected to provide an indication of organ function, e.g., the onset of shock.Type: ApplicationFiled: December 13, 2000Publication date: June 13, 2002Inventors: William P. Wiesmann, Adrian Richard Urias, Jill Uyeno, Adrian Prokop, Jason Milne, Kristopher Jurka, Farbod Ghassemi