Patents by Inventor Adrian Rice

Adrian Rice has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TUMOR VACCINATION USING PROSTATE CANCER-ASSOCIATED ANTIGENS
    Publication number: 20190125852
    Abstract: Methods and compositions for constructing and producing recombinant adenovirus-based vector vaccines are provided. In particular aspects, there are be provided compositions and methods involving adenovirus vectors comprising genes for target antigens, such as pro state-specific antigen (PSA), pro state-specific membrane antigen (PSMA), MUC1, CEA, and/or Brachyury, and costimulatory molecules for use in treatment methods that generate highly reactive anti-tumor immune responses and that allows for multiple vaccinations in individuals with preexisting immunity to adenovirus.
    Type: Application
    Filed: June 2, 2017
    Publication date: May 2, 2019
    Inventors: Frank R. JONES, Joseph BALINT, Yvette LATCHMAN, Adrian RICE, Elizabeth GABITZSCH
  • METHODS AND COMPOSITIONS FOR T-CELL IMMUNOTHERAPY
    Publication number: 20190030151
    Abstract: Genetically modified compositions, such as adenoviral vectors and T cells, for treating diseases such as cancer and infectious diseases are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating diseases such as cancer and infectious diseases.
    Type: Application
    Filed: January 13, 2017
    Publication date: January 31, 2019
    Inventors: Frank R. Jones, Elizabeth Gabitzsch, Yvette Latchman, Adrian Rice
  • METHODS AND COMPOSITIONS FOR INFLUENZA VACCINATION
    Publication number: 20190022209
    Abstract: Methods for constructing and producing a recombinant adenovirus based vector vaccine containing multiple influenza antigen genes for use in generating broad based immune responses against influenza A and B viruses and that allows for multiple vaccinations in individuals with preexisting immunity to adenovirus are described. Specifically, the recombinant adenovirus based vector is a replication defective adenovirus vector comprising a deletion in an early 2b (E2b) gene.
    Type: Application
    Filed: January 13, 2017
    Publication date: January 24, 2019
    Inventors: Frank R. Jones, Joseph Balint, Elizabeth Gabitzsch, Yvette Latchman, Adrian Rice
  • METHODS AND COMPOSITIONS FOR COMBINATION IMMUNOTHERAPY
    Publication number: 20180344832
    Abstract: Methods and compositions for generating immune responses using adenovirus vectors that allow multiple vaccinations or in combination with other therapy and vaccinations in individuals with preexisting immunity to adenovirus are provided.
    Type: Application
    Filed: April 20, 2016
    Publication date: December 6, 2018
    Inventors: Frank R. JONES, Elizabeth GABITZSCH, Yvette LATCHMAN, Adrian RICE
  • METHODS AND COMPOSITIONS FOR COMBINATION IMMUNOTHERAPY
    Publication number: 20180187211
    Abstract: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
    Type: Application
    Filed: January 7, 2016
    Publication date: July 5, 2018
    Inventors: Frank R. Jones, Elizabeth Gabitzsch, Yvette Latchman, Adrian Rice