Patents by Inventor Adrian Schwartz Mittelman

Adrian Schwartz Mittelman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acids encoding anti-VEGF-A antibodies and uses thereof
    Patent number: 11634483
    Abstract: The present invention relates to antibodies having activity against a vascular endothelial growth factor (VEGF), and methods of making and using such antibodies.
    Type: Grant
    Filed: January 19, 2021
    Date of Patent: April 25, 2023
    Assignee: MEDIMMUNE LIMITED
    Inventors: Ching Ching Leow, Nazzareno Dimasi, Karen Coffman, Ping Tsui, Changshou Gao, Mario A. Cepeda, Adrian Schwartz Mittelman
  • Nucleic acids encoding bispecific anti-VEGF and anti-ANG2 antibodies and uses thereof
    Patent number: 11566068
    Abstract: The present invention relates to bispecific antibodies having activity against a vascular endothelial growth factor (VEGF) and an angiopoietin (ANG), and methods of making and using such bispecific antibodies.
    Type: Grant
    Filed: October 14, 2020
    Date of Patent: January 31, 2023
    Assignee: MEDIMMUNE LIMITED
    Inventors: Ching Ching Leow, Nazzareno Dimasi, Karen Coffman, Ryan Fleming, Ping Tsui, Changshou Gao, Mario A. Cepeda, Adrian Schwartz Mittelman
  • ANTI-VEGF-A ANTIBODIES AND USES THEREOF
    Publication number: 20210147531
    Abstract: The present invention relates to antibodies having activity against a vascular endothelial growth factor (VEGF), and methods of making and using such antibodies.
    Type: Application
    Filed: January 19, 2021
    Publication date: May 20, 2021
    Applicant: MEDIMMUNE LIMITED
    Inventors: Ching Ching Leow, Nazzareno Dimasi, Karen Coffman, Ping Tsui, Changshou Gao, Mario A. Cepeda, Adrian Schwartz Mittelman
  • Anti-VEGF-A antibodies and uses thereof
    Patent number: 10919958
    Abstract: The present invention relates to antibodies having activity against a vascular endothelial growth factor (VEGF), and methods of making and using such antibodies.
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: February 16, 2021
    Assignee: MEDIMMUNE LIMITED
    Inventors: Ching Ching Leow, Nazzareno Dimasi, Karen Coffman, Ping Tsui, Changshou Gao, Mario A. Cepeda, Adrian Schwartz Mittelman
  • ANTI-VEGF-A AND ANTI-ANG2 ANTIBODIES AND USES THEREOF
    Publication number: 20210040194
    Abstract: The present invention relates to bispecific antibodies having activity against a vascular endothelial growth factor (VEGF) and an angiopoietin (ANG), and methods of making and using such bispecific antibodies.
    Type: Application
    Filed: October 14, 2020
    Publication date: February 11, 2021
    Applicant: MEDIMMUNE LIMITED
    Inventors: Ching Ching Leow, Nazzareno Dimasi, Karen Coffman, Ryan Fleming, Ping Tsui, Changshou Gao, Mario A. Cepeda, Adrian Schwartz Mittelman
  • Anti-VEGF-A and anti-ANG2 antibodies and uses thereof
    Patent number: 10836819
    Abstract: The present invention relates to bispecific antibodies having activity against a vascular endothelial growth factor (VEGF) and an angiopoietin (ANG), and methods of making and using such bispecific antibodies.
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: November 17, 2020
    Assignee: MEDIMMUNE LIMITED
    Inventors: Ching Ching Leow, Nazzareno Dimasi, Karen Coffman, Ryan Fleming, Ping Tsui, Changshou Gao, Mario A. Cepeda, Adrian Schwartz Mittelman
  • ANTI-VEGF-A ANTIBODIES AND USES THEREOF
    Publication number: 20190202903
    Abstract: The present invention relates to antibodies having activity against a vascular endothelial growth factor (VEGF), and methods of making and using such antibodies.
    Type: Application
    Filed: August 22, 2017
    Publication date: July 4, 2019
    Inventors: Ching Ching Leow, Nazzareno Dimasi, Karen Coffman, Ping Tsui, Changshou Gao, Mario A. Cepeda, Adrian Schwartz Mittelman
  • ANTI-VEGF-A AND ANTI-ANG2 ANTIBODIES AND USES THEREOF
    Publication number: 20190194308
    Abstract: The present invention relates to bispecific antibodies having activity against a vascular endothelial growth factor (VEGF) and an angiopoietin (ANG), and methods of making and using such bispecific antibodies.
    Type: Application
    Filed: August 22, 2017
    Publication date: June 27, 2019
    Inventors: Ching Ching Leow, Nazzareno Dimasi, Karen Coffman, Ryan Fleming, Ping Tsui, Changshou Gao, Mario A. Cepeda, Adrian Schwartz Mittelman
  • Methods for generating and screening fusion protein libraries and uses thereof
    Patent number: 9109223
    Abstract: The invention provides methods for generating fusion protein libraries, such as immunotoxin libraries. The invention also relates to libraries of recombinant cells encoding nucleic acid sequences comprising fusion proteins. In addition, the invention relates to the libraries themselves and the use of the libraries to screen for fusion proteins that are specific for target cells, such as cancer cells. Further, the invention relates to methods of improving fusion proteins and to the improved fusion proteins.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: August 18, 2015
    Assignee: Viventia Bio, Inc.
    Inventors: Adrian Schwartz Mittelman, Jeannick Cizeau, Nicholas Ronald Glover, Glen Christopher MacDonald
  • Methods for Generating and Screening Fusion Protein Libraries and Uses Thereof
    Publication number: 20090075878
    Abstract: The invention provides methods for generating fusion protein libraries, such as immunotoxin libraries. The invention also relates to libraries of recombinant cells encoding nucleic acid sequences comprising fusion proteins. In addition, the invention relates to the libraries themselves and the use of the libraries to screen for fusion proteins that are specific for target cells, such as cancer cells. Further, the invention relates to methods of improving fusion proteins and to the improved fusion proteins.
    Type: Application
    Filed: December 22, 2006
    Publication date: March 19, 2009
    Inventors: Adrian Schwartz Mittelman, Jeannick Cizeau, Nicholas R. Glover, Glen MacDonald