Abstract: The invention provides a compound of formula (I), or pharmaceutically acceptable ester, amide, carbamate, solvate or salt thereof, including a salt of such an ester, amide or carbamate, wherein R1 is an optionally substituted phenyl, or an optionally substituted 5- or 6-membered aromatic heterocycle; and R2 is an optionally substituted 5- or 6-membered aromatic heterocycle. Also provided are pharmaceutical compositions comprising a compound of formula (I).

Abstract: A method for providing directed transmission of sound waves, through modulation on an ultrasonic carrier, may comprise connecting at least one directed sound source to an audio system; emitting, via the at least one directed sound source, audio from the audio system, wherein the emitting comprises emitting medium-frequency audio waves and higher-frequency audio waves. The audio may be selected via a master control unit (MCU), which may be operatively coupled to a mobile application. In some embodiments, a first audio selection is configured to be heard only through a first directed sound source, and a second audio selection is configured to be heard only through a second directed sound source.

Abstract: Systems and methods are provided herein for directing sound through a parametric speaker in connection with interpreting/translating messages in an open forum such that communications may be delivered and understood without the use of headphones. The directed sound may also be directed in connection with detecting auditory areas and targeting sound at the auditory regions of a subject.

Abstract: A method for providing directed transmission of sound waves, through modulation on an ultrasonic carrier, may comprise connecting at least one directed sound source to an audio system; emitting, via the at least one directed sound source, audio from the audio system, wherein the emitting comprises emitting medium-frequency audio waves and higher-frequency audio waves. The audio may be selected via a master control unit (MCU), which may be operatively coupled to a mobile application. In some embodiments, a first audio selection is configured to be heard only through a first directed sound source, and a second audio selection is configured to be heard only through a second directed sound source.

Abstract: A method for providing directed transmission of sound waves, through modulation on an ultrasonic carrier, may comprise connecting at least one directed sound source to an audio system; emitting, via the at least one directed sound source, audio from the audio system, wherein the emitting comprises emitting medium-frequency audio waves and higher-frequency audio waves. The audio may be selected via a master control unit (MCU), which may be operatively coupled to a mobile application. In some embodiments, a first audio selection is configured to be heard only through a first directed sound source, and a second audio selection is configured to be heard only through a second directed sound source.

Abstract: Systems and methods are provided herein for directing sound through a parametric speaker in connection with interpreting/translating messages in an open forum such that communications may be delivered and understood without the use of headphones. The directed sound may also be directed in connection with detecting auditory areas and targeting sound at the auditory regions of a subject.

Abstract: A method is provided for delivering directed transmission of sound waves through modulation on an ultrasonic carrier. In some embodiments, the method comprises connecting at least one directed sound source to an audio system and emitting, via the at least one directed sound source, audio from the audio system, wherein the emitting comprises emitting medium frequency audio sound waves and higher frequency audio sound waves. The audio may be selected via a master control unit, operatively coupled to a mobile application. In some embodiments, a first audio selection is configured to be heard only through a first directed sound source, and a second audio selection is configured to be heard only through a second directed sound source. Additionally, systems and methods are provided for delivering therapeutic sound, through a sinusoidal signal, within an environment intended to cause resonance in certain cells.

Abstract: Systems and methods herein provide directed sound to venues, including a queue line and locations offering multiple viewing devices with different audio streams. Directed sound can be sent to various locations in the queue line to reach specific individuals, positions in the queue line, etc. A queue rate may be used to determine current locations in the queue line. The directed transmission of sound waves can provide the directed sound through modulation of the sound on an ultrasonic carrier. In connection with directing sound to a specific location in a venue, one or more individuals can be tracked according to an indoor positioning system to send a sound message using a modulated ultrasonic carrier.

Abstract: A method for providing directed transmission of sound waves, through modulation on an ultrasonic carrier, may comprise connecting, at least one directed sound source to an audio system, emitting, via the at least one directed sound source, audio from the audio system, wherein the emitting comprises emitting medium frequency audio sound waves and higher frequency audio sound waves. The audio may be selected via a master control unit, which may be operatively coupled to a mobile application. In many embodiments, a first audio selection is configured to be heard only through a first directed sound source, and a second audio selection is configured to be heard only through a second directed sound source.

Abstract: Disclosed is a method for producing a palladium-based permeation membrane which is suitable for the separation of hydrogen from gas-gas or liquid-gas mixtures. The permeation membrane is produced by applying a palladium complex, dissolved in a solvent, to a nanoporous support system having pores in a size range of from 0.5 nm to 50 nm, removing the solvent by drying, removing of organic constituents of the palladium complex by a heat treatment, and carrying out a final heat treatment under reducing conditions at a temperature ranging from about 300° C. to about 900° C.

Abstract: Disclosed is a method for producing a palladium-based permeation membrane which is suitable for the separation of hydrogen from gas-gas or liquid-gas mixtures. The permeation membrane is produced by applying a palladium complex, dissolved in a solvent, to a nanoporous support system having pores in a size range of from 0.5 nm to 50 nm, removing the solvent by drying, removing of organic constituents of the palladium complex by a heat treatment, and carrying out a final heat treatment under reducing conditions at a temperature ranging from about 300° C. to about 900° C.

Abstract: Disclosed is a permeation membrane and a method for producing a permeation membrane. The permeation membrane can be used in particular in the field of membrane-based material separations. The permeation membrane is composed of an inorganic semi-permeable substance in which an additional substance is incorporated in some locations such that existing intermediate spaces in the semi-permeable substance are at least partly filled by the additional substance and thus only the intermediate spaces are blocked for a permeating species.

Abstract: A method of processing a remotely sensed multispectral or hyperspectral image captured in respect of an area of interest including a body of water so as to identify a submerged target, the method comprising obtaining (206), from hydrographic LiDAR measurements, data representative of water depth in respect of said body of water in said area of interest, performing (210) geo-rectification in respect of said hyperspectral image and said water depth data, applying a hydrologic radiative analysis process (211) to said multispectral or hyperspectral image so as to calculate, using said water depth data obtained from said hydrographic LiDAR measurements, data representative of (i) scattered solar radiation and (ii) spectral transmission between a surface of said body of water and a submerged target and subtracting (212) data representative of said scattered solar radiation from said multispectral or hyper spectral image and multiplying a resultant image by data representative of said spectral transmission so as to

Abstract: A method and apparatus for monitoring the movement and activity of targets is provided. The method comprises the steps of initially detecting electromagnetic (EM) radiation reflected by the target and recording spectral information relating to it and detecting EM radiation reflected by a target at a later time and again recording spectral information relating to it. The spectral information relating to the initially detected and later detected targets is then compared, so as to establish whether the initially detected and later detected targets are the same.

Abstract: A system and method are disclosed for detecting a target within a scene. The system comprises a sensor for acquiring hyperspectral image data of the scene, a repository for storing a set of target spectra and a processor for processing spectra generated from locations within the scene with the known set of target spectra. The processor is further arranged to generate a probability that the spectra generated from locations within the scene correspond with one or more target spectra based on the comparison between the spectra generated from locations within the scene with the target spectra.

Abstract: An ionic conduction device of the kind including a tri-layer including an electrolytic membrane having a pair of opposed surfaces, and a gas permeable electrode in contact with each opposed surface. The device has a first gas flow path for a first gas across one of the opposed surfaces, and second gas flow path for a second gas across the one of the opposed surfaces, and a third gas flow path for a third gas along the other of the opposed surfaces of the membrane. The device includes a fourth flow path through the device for a heat exchanging fluid. The fourth flow path bringing the heat exchanging fluid into heat exchange relationship with the tri-layer.

Abstract: A method of operating a life support system for an aircraft, the system including a plurality of oxygen supply apparatus, each of which in use is operable to supply product gas, which may be pure oxygen or oxygen enriched gas, to a breathing gas supply apparatus, at least one of the oxygen supply apparatus being a main oxygen supply apparatus and the remainder of the oxygen supply apparatus being auxiliary oxygen supply apparatus, the main oxygen supply apparatus being operable independently of the auxiliary oxygen supply apparatus, characterized in that the method includes operating the main oxygen supply apparatus and supplying product gas to each of the auxiliary oxygen supply apparatus.

Abstract: An ionic conduction device of the kind including a tri-layer including an electrolytic membrane having a pair of opposed surfaces, and a gas permeable electrode in contact with each opposed surface. The device has a first gas flow path for a first gas across one of the opposed surfaces, and second gas flow path for a second gas across the one of the opposed surfaces, and a third gas flow path for a third gas along the other of the opposed surfaces of the membrane. The device includes a fourth flow path through the device for a heat exchanging fluid. The fourth flow path bringing the heat exchanging fluid into heat exchange relationship with the tri-layer.

Abstract: A method of operating a life support system for an aircraft, the system including a plurality of oxygen supply apparatus, each of which in use is operable to supply product gas, which may be pure oxygen or oxygen enriched gas, to a breathing gas supply apparatus, at least one of the oxygen supply apparatus being a main oxygen supply apparatus and the remainder of the oxygen supply apparatus being auxiliary oxygen supply apparatus, the main oxygen supply apparatus being operable independently of the auxiliary oxygen supply apparatus, characterized in that the method includes operating the main oxygen supply apparatus and supplying product gas to each of the auxiliary oxygen supply apparatus.

Abstract: A gas generating system for generating a supply of oxygen or at least an oxygen rich gas, and a residual gas, the system including a first gas separation device for separating from a supply gas, a first gas being oxygen enriched gas, to leave a residual gas. The first oxygen enriched gas from the first gas separation device is communicated to a second gas separation device for further separating from the first oxygen enriched gas, oxygen gas. The second gas separation device generating a product gas which is at least highly oxygen enriched and a further residual gas, with at least one of the first and second gas separating devices including a ceramic membrane through which in use gas ions diffuse.