Abstract: Transgenic T cells and vectors for making transgenic T cells are described. The vectors can include a nucleic acid encoding a membrane-bound anti-IL6 (mb-alL6) single chain variable fragment (scFv), and the transgenic T cells can express mb-alL6. The transgenic T cells are useful for suppressing proliferation of IL-6-dependent cells, reducing IL-6 concentration, or both. In one embodiment, the vector is a bicistronic construct encoding the mb-alL6 and an anti-CD19-41 BB-003? chimeric antigen receptor (CAR). In another embodiment, an anti-IL-6 scFv can be linked to a 41 BB and 003? domains to form an anti-IL-6 CAR. The transgenic T cells expressing said constructs can reduce the linker risk of cytokine release syndrome (CRS) in cancer patients being treated with CAR T cell or for the treatment of autoimmune diseases and inflammatory diseases in which cytokines are involved in pathogenesis.

Abstract: A vehicle display configuration system and method employs a display, an eye tracker and a controller. The eye tracker is configured to track eye movement of a user viewing the display. The controller is configured to control the display to sequentially display sets of a plurality of images for comparison and selection by the user, to receive selection information representing a respective selected image from each of the sets being displayed on the display as selected by the user, to analyze eye tracker eye movement information received from the eye tracker representing eye movement of the user while the user is viewing each of the sets being displayed on the display, and to designate a vehicle display image based on the selection information and a result of the analysis of the eye movement information.

Abstract: A multi-device in-vehicle-infotainment system is configured to playback audio files one after another using a media device shuffling operation and an audio file shuffling operation. Specifically, in response to instructions from a user interface, a controller is further configured to automatically provide a plurality of audio files, one audio file after another, to an audio output component where the controller selects the plurality of audio files randomly shuffling between a plurality of electronic media devices selecting one or more audio files from differing ones of the plurality of electronic media devices for audio playback.

Abstract: A vehicle shade assembly includes a vehicle body structure, a cover supporting structure, a cover material, an electronic display and a controller. The vehicle body structure defines an opening with a transparent material installed within the opening. The cover supporting structure is installed to the vehicle body structure adjacent to the opening. The cover material is supported to the cover supporting structure and is movable from a closed orientation covering the opening and the transparent material and an open orientation exposing the opening and the transparent material. The electronic display is installed to the cover material for movement therewith. The controller is configured to operate the display to display content thereon.

Abstract: A system for ride sharing with commercial transport vehicles, the system includes a receiver, an input device, and an electronic controller. The receiver is configured to receive information regarding a predetermined route for at least one commercial transport vehicle. The input device is configured to enable a user to input information including location and destination. The electronic controller is configured to determine whether the predetermined route for the at least one commercial transport vehicle passes within a predetermined distance from the location and travels in a direction toward the destination, and when the predetermined route for the at least one commercial transport vehicle passes within the predetermined distance from the location and travels in the direction toward the destination, the electronic controller is configured to notify the commercial transport vehicle and the user.

Abstract: A vehicle object detection system having a controller configured to process object information received from the plurality of sensors and determine the distance between an outer surface of a vehicle body structure and an object. The controller displays on a video display a faux representation of the object, a faux representation of the outer surface of the vehicle body structure and a numeric representation of the distance between the outer surface of the vehicle body structure and the object. The controller is further configured to switch between operating the video display in display modes including a parallel parking view mode and a backup mode.

Abstract: An autonomous vehicle seat positioning system has a controller connected to a display, a control panel and a positioning mechanism of a vehicle seat assembly. The controller operates in a position saving mode and a position selecting mode. In the position saving mode, positioning inputs made by the first occupant are saved in memory as a first upright setting corresponding to the first occupant manually driving the vehicle. Positioning inputs made by the first occupant of the vehicle seat assembly are also saved in memory as a first relaxation setting corresponding to the first occupant viewing the display with the vehicle operating in a self-driving mode. In the position selecting mode, the controller operates the positioning mechanism to move the vehicle seat assembly to positions corresponding the first upright setting or the first relaxation setting.

Abstract: A vehicle tutorial system includes a data storage device having at least one vehicle tutorial, an on-board identification sensor, an on-board vehicle communication device, a tutorial manager device located in a cloud computer and/or the remote device, and an on-board vehicle controller. The on-board vehicle controller is programmed to identify the user of the vehicle based on information from the on-board identification sensor, select the vehicle tutorial, select the remote device associated with the user of the vehicle, offer the vehicle tutorial to the user at a first time, and upon the user declining the offer at the first time, send the vehicle tutorial to the tutorial manager device. The tutorial manager device includes a processor programmed to offer the vehicle tutorial to the user at a time later than the first time on the on-board vehicle display or on the remote device.

Abstract: A vehicle connection maintenance system includes a receiver, a transmitter, an electronic controller. The receiver is disposed in a vehicle and is configured to receive a signal from a portable device to enable the portable device to wirelessly connect to a connection system in the vehicle. The transmitter is disposed in the vehicle and is configured to transmit information related to the portable device. The electronic controller is configured to the cause the transmitter to transmit information when the receiver has received the signal from the portable device and the portable device is connected to the connection system of the vehicle to maintain wireless connection between the portable device and the connection system of the vehicle and prevent the portable device from wirelessly connecting to a remote system, the information indicating that the portable device is wirelessly connected to the connection system in the vehicle.

Abstract: A vehicle display configuration system and method employs a display, an eye tracker and a controller. The eye tracker is configured to track eye movement of a user viewing the display. The controller is configured to control the display to sequentially display sets of a plurality of images for comparison and selection by the user, to receive selection information representing a respective selected image from each of the sets being displayed on the display as selected by the user, to analyze eye tracker eye movement information received from the eye tracker representing eye movement of the user while the user is viewing each of the sets being displayed on the display, and to designate a vehicle display image based on the selection information and a result of the analysis of the eye movement information.

Abstract: An autonomous vehicle seat positioning system includes a seat controller connected to a autonomous vehicle controller and a positioning mechanism of a seat assembly.

Abstract: A multi-device in-vehicle-infotainment system is configured to playback audio files one after another using a media device shuffling operation and an audio file shuffling operation. Specifically, in response to instructions from a user interface, a controller is further configured to automatically provide a plurality of audio files, one audio file after another, to an audio output component where the controller selects the plurality of audio files randomly shuffling between a plurality of electronic media devices selecting one or more audio files from differing ones of the plurality of electronic media devices for audio playback.

Abstract: An autonomous vehicle seat positioning system includes a seat controller connected to a autonomous vehicle controller and a positioning mechanism of a seat assembly.

Abstract: An autonomous vehicle seat positioning system has a controller connected to a display, a control panel and a positioning mechanism of a vehicle seat assembly. The controller operates in a position saving mode and a position selecting mode. In the position saving mode, positioning inputs made by the first occupant are saved in memory as a first upright setting corresponding to the first occupant manually driving the vehicle. Positioning inputs made by the first occupant of the vehicle seat assembly are also saved in memory as a first relaxation setting corresponding to the first occupant viewing the display with the vehicle operating in a self-driving mode. In the position selecting mode, the controller operates the positioning mechanism to move the vehicle seat assembly to positions corresponding the first upright setting or the first relaxation setting.

Abstract: A vehicle shade assembly includes a vehicle body structure, a cover supporting structure, a cover material, an electronic display and a controller. The vehicle body structure defines an opening with a transparent material installed within the opening. The cover supporting structure is installed to the vehicle body structure adjacent to the opening. The cover material is supported to the cover supporting structure and is movable from a closed orientation covering the opening and the transparent material and an open orientation exposing the opening and the transparent material. The electronic display is installed to the cover material for movement therewith. The controller is configured to operate the display to display content thereon.

Abstract: A vehicle tutorial system includes a data storage device having at least one vehicle tutorial, an on-board identification sensor, an on-board vehicle communication device, a tutorial manager device located in a cloud computer and/or the remote device, and an on-board vehicle controller. The on-board vehicle controller is programmed to identify the user of the vehicle based on information from the on-board identification sensor, select the vehicle tutorial, select the remote device associated with the user of the vehicle, offer the vehicle tutorial to the user at a first time, and upon the user declining the offer at the first time, send the vehicle tutorial to the tutorial manager device. The tutorial manager device includes a processor programmed to offer the vehicle tutorial to the user at a time later than the first time on the on-board vehicle display or on the remote device.

Abstract: A vehicle object detection system having a controller configured to process object information received from the plurality of sensors and determine the distance between an outer surface of a vehicle body structure and an object. The controller displays on a video display a faux representation of the object, a faux representation of the outer surface of the vehicle body structure and a numeric representation of the distance between the outer surface of the vehicle body structure and the object. The controller is further configured to switch between operating the video display in display modes including a parallel parking view mode and a backup mode.

Abstract: An object detection system is configured to detect location of an object proximate a first surface of a vehicle. A beacon is configured to be positioned and repositioned relative to the vehicle. A controller is configured to process data from the object detection system and position data from the beacon. The controller is configured to define a first zone of interest relative to the first surface of the vehicle body structure without the beacon and further process object location data from the object detection system and output the object location data to the display relative to the first zone of interest. The controller determines current location of the beacon relative to the first surface of the vehicle body structure, defines a second zone of interest relative to the beacon and outputs the object location data to a display relative to the second zone of interest.

Abstract: A vehicle may traverse a portion of a vehicle transportation network, which may include a processor of the vehicle executing instructions to identify a first vehicle operation assistance information item, and, on a condition that an immanency for the first vehicle operation assistance information item is within a maximum relevant immanence and a utility metric for the first vehicle operation assistance information item indicates high utility, present a representation of the first vehicle operation assistance information item by, on a condition that a first urgency identified based on the immanency indicates a warning urgency or an advisory urgency, controlling a primary graphical display portion to present a first portion of a graphical representation of the first vehicle operation assistance information item, and controlling a secondary graphical display portion to present a second portion of the graphical representation.

Abstract: A vehicle HVAC noise control system includes an air handler, a blower motor, an audio event device and a controller. The air handler is connected to a passenger compartment. The blower motor is operably connected to the air handler to provide a plurality of airflow rates for air flowing into a passenger compartment. The audio event device produces an audio event to the passenger compartment. The controller is operatively connected to the blower motor and the audio event device. The controller controls operation of the blower motor initially at an operating airflow rate and subsequently switches to a noise reducing airflow rate in response to a signal from the audio event device indicating that the audio event device will subsequently produce the audio event.