Abstract: The present disclosure provides methods of determining the susceptibility of a dog to liver copper accumulation, comprising detecting in a biological sample obtained from the dog the presence or absence in the genome of the dog of one or more polymorphisms, and methods of treating or breeding the dog based on such determination.

Abstract: The present disclosure provides an animal food composition comprising a source of glycyrrhizin, in combination with a source of curcuminoids, for use for preventing and/or treating allergic inflammatory skin diseases.

Abstract: The present invention relates to the use of a diet or foodstuff comprising linoleic acid in an amount ranging from 7 g/Mcal to 9 g/Mcal for sustaining or improving skin quality of a healthy pet. In some embodiments, the diet or foodstuff further comprises zinc in an amount of about 50 mg/Mcal. It further pertains to a diet or foodstuff comprising linoleic acid in an amount ranging from 7 g/Mcal to 9 g/Mcal for use in a method for treating a pet animal affected with a skin disorder or disease.

Abstract: A method includes transmitting, over a virtual private network (VPN) to a remotely-located control platform, a request for first information associated with a BOOTP protocol synchronization process. The method also includes receiving, from the control platform, a first response comprising the requested first information. The method further includes receiving, over a local network from an embedded device in a distributed control system, a request for second information associated with the BOOTP protocol. In addition, the method includes transmitting, to the embedded device, a second response comprising the requested second information.

Abstract: The present disclosure provides methods of determining the susceptibility of a dog to liver copper accumulation, comprising detecting in a biological sample obtained from the dog the presence or absence in the genome of the dog of one or more polymorphisms, and methods of treating or breeding the dog based on such determination.

Abstract: The present invention provides a method of testing a dog to determine the susceptibility of the dog to liver copper accumulation, comprising detecting in a sample the presence or absence in the genome of the dog of one or more polymorphisms selected from: (a) Chr22_3167534 (SEQ ID NO: 144), Chr22_3135144 (SEQ ID NO: 145), Chr20_55461150 (SEQ ID NO: 146), ChrX_120879711 (SEQ ID NO: 147), Chr19_6078084 (SEQ ID NO: 148), Chr15_62625262 (SEQ ID NO: 149), Chr14_39437543 (SEQ ID NO: 150), Chr15_62625024 (SEQ ID NO: 151), Chr3_86838677 (SEQ ID NO: 152), Chr24_4011833 (SEQ ID NO: 153), Chr18_60812198 (SEQ ID NO: 154), Chr10_65209946 (SEQ ID NO: 155), and the CGCCCC repeat at chromosome location 22:3135287; (b) one or more polymorphisms in linkage disequilibrium with a said polymorphism (a); and/or (c) Chr32_38904515 (SEQ ID NO: 156), Chr8_4892743 (SEQ ID NO: 157) and Chr8_4880518 (SEQ ID NO: 158).

Abstract: A method includes transmitting, over a virtual private network (VPN) to a remotely-located control platform, a request for first information associated with a BOOTP protocol synchronization process. The method also includes receiving, from the control platform, a first response comprising the requested first information. The method further includes receiving, over a local network from an embedded device in a distributed control system, a request for second information associated with the BOOTP protocol. In addition, the method includes transmitting, to the embedded device, a second response comprising the requested second information.

Abstract: The present invention provides a method of testing a dog to determine the susceptibility of the dog to liver copper accumulation, comprising detecting in a sample the presence or absence in the genome of the dog of one or more polymorphisms selected from: (a) Chr22_3167534 (SEQ ID NO: 144), Chr22_3135144 (SEQ ID NO: 145), Chr20_55461150 (SEQ ID NO: 146), ChrX_120879711 (SEQ ID NO: 147), Chr19_6078084 (SEQ ID NO: 148), Chr15_62625262 (SEQ ID NO: 149), Chr14_39437543 (SEQ ID NO: 150), Chr15_62625024 (SEQ ID NO: 151), Chr3_86838677 (SEQ ID NO: 152), Chr24_4011833 (SEQ ID NO: 153), Chr18_60812198 (SEQ ID NO: 154), Chr10_65209946 (SEQ ID NO: 155), and the CGCCCC repeat at chromosome location 22:3135287; (b) one or more polymorphisms in linkage disequilibrium with a said polymorphism (a); and/or (c) Chr32_38904515 (SEQ ID NO: 156), Chr8_4892743 (SEQ ID NO: 157) and Chr8_4880518 (SEQ ID NO: 158).

Abstract: The present invention relates to the use of an electrostatically charged cloth for reducing the allegenicity of an animal. It also relates to a method of reducing the allegenicity of an animal, using such a cloth. It also relates to an animal grooming device comprising an electrostatically charged cloth.

Abstract: A method of operating a gaming machine/a gaming machine (10) comprising a display (14), a game controller (36) to control the play of the game, and control images displayed on the display, the game is a spinning reel game (FIG. 3) comprising a plurality of symbols that are separated into a plurality of symbol sets (FIG. 9), each set of symbols is associated with a distinct reel, a combined symbol is defined by the combination of a symbol from one symbol set with at least one symbol from at least one other symbol set but not with at least some other symbols from the at least one other symbol set (62, 64), during the play of the game, representations of the game are displayed on the display showing a random selection of plurality of symbols from each symbol set and prize is awardable only when a matching combined symbol (52, 54, 56, 58, 62, 64) is displayed on the display.

Abstract: The present invention provides a composition preferably a pet foodstuff comprising pantothenic acid, nicotinamide, histidine, inositol and choline wherein pantothenic acid is provided at a level of 10 mg to 500 mg per 400 kcal per day, its use in the treatment of a skin disorder and methods of controlling a skin disorder. The invention further provides a method of manufacturing a composition of the invention.

Abstract: This invention relates to a promoter and to a fungal host for improved protein production. According to the invention the promoter has been modified in its response to the mechanisms mediating transcriptional down-regulation of secreted proteins under secretion stress. This invention relates also to methods for optimised protein production of secretable proteins in fungi.