Patents by Inventor Adrian WILLIG

Adrian WILLIG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CAPTURE PROBES AND USES THEREOF
    Publication number: 20250129433
    Abstract: The present invention is directed to the probes for detecting known and unknown fusion genes, related methods of detection of fusion genes, uses and kits related thereto. In particular, the invention relates to methods of diagnosing and monitoring of a cancer.
    Type: Application
    Filed: August 16, 2024
    Publication date: April 24, 2025
    Applicant: Sophia Genetics S.A.
    Inventors: Gabriela ECCO, Xiaobin XING, Adrian WILLIG, Zhenyu XU, Izabela Maria Matyszczak, Elia Magrinelli
  • Capture probes and uses thereof
    Patent number: 12247255
    Abstract: The present invention is directed to the probes for detecting known and unknown fusion genes, related methods of detection of fusion genes, uses and kits related thereto. In particular, the invention relates to methods of diagnosing and monitoring of a cancer.
    Type: Grant
    Filed: September 24, 2021
    Date of Patent: March 11, 2025
    Assignee: SOPHIA GENETICS S.A.
    Inventors: Gabriela Ecco, Xiaobin Xing, Adrian Willig, Zhenyu Xu
  • CAPTURE PROBES AND USES THEREOF
    Publication number: 20220380843
    Abstract: The present invention is directed to the probes for detecting known and unknown fusion genes, related methods of detection of fusion genes, uses and kits related thereto. In particular, the invention relates to methods of diagnosing and monitoring of a cancer.
    Type: Application
    Filed: September 24, 2021
    Publication date: December 1, 2022
    Applicant: Sophia Genetics S.A.
    Inventors: Gabriela ECCO, Xiaobin XING, Adrian WILLIG, Zhenyu XU
  • METHODS FOR DNA LIBRARY GENERATION TO FACILITATE THE DETECTION AND REPORTING OF LOW FREQUENCY VARIANTS
    Publication number: 20220364080
    Abstract: Methods are disclosed for adding adapters to fragmented nucleic acids for next generation sequencing, including providing numerical codes based on variable adapter molecular barcode lengths on both sides of the fragmented nucleic acids and identifying reads from the same fragment based on both barcodes. The methods and products allow for the amplification of the fragmented nucleic acids when there is a low yield of isolated fragmented nucleic acids and also for efficient and reliable detection of low-frequency mutations including in subpopulations of cells within a subject.
    Type: Application
    Filed: September 21, 2020
    Publication date: November 17, 2022
    Applicant: Sophia Genetics S.A.
    Inventors: Morgane MACHERET, Christian POZZORINI, Adrian WILLIG, Jonathan BIELER, Zhenyu XU