Patents by Inventor Adrian Zuercher

Adrian Zuercher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RECOMBINANT IgG Fc MULTIMERS FOR THE TREATMENT OF IMMUNE COMPLEX-MEDIATED KIDNEY DISORDERS
    Publication number: 20220332847
    Abstract: The invention relates to the use of recombinant IgG Fc multimers for the treatment of immune complex-mediated kidney disorders, and methods of treating immune complex-mediated kidney disorders by administering such multimers.
    Type: Application
    Filed: September 11, 2020
    Publication date: October 20, 2022
    Inventors: Helen Zhihui CAO, Rolf SPIRIG, Adrian ZUERCHER, Adriana BAZ MORELLI
  • RECOMBINANT IGG FC MULTIMERS
    Publication number: 20190119377
    Abstract: This disclosure provides recombinant IgG Fc multimers and methods of treating autoimmune and inflammatory diseases by administering such multimers.
    Type: Application
    Filed: January 27, 2017
    Publication date: April 25, 2019
    Inventors: Rolf SPIRIG, Fabian KAESERMANN, Adrian ZUERCHER, Con PANOUSIS, Adriana BAZ MORELLI, Chao-Guang CHEN
  • Compositions comprising secretory-like immunoglobulins
    Patent number: 10221233
    Abstract: The invention relates to methods for preparing compositions comprising secretory-like immunoglobulin, in particular secretory-like IgA and/or secretory-like IgM, and compositions obtainable by the methods.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: March 5, 2019
    Assignee: CSL BEHRING AG
    Inventors: Blaise Corthésy, Stéphanie Longet, Marius Loetscher, Sylvia Miescher, Adrian Zuercher
  • Prevention of infection
    Patent number: 9932392
    Abstract: The invention relates to compositions and methods to prevent enteric infection in a subject at risk of such infection. In particular, the invention relates to the prevention of recurrence of infection by Clostridium difficile.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: April 3, 2018
    Assignees: CSL BEHRING AG, BETH ISRAEL DEACONESS MEDICAL CENTER INC
    Inventors: Ciaran Kelly, Xinhua Chen, Sylvia Miescher, Martin Spycher, Sandra Wymann, Adrian Zuercher
  • CD89 ACTIVATION IN THERAPY
    Publication number: 20170166640
    Abstract: The invention relates to the use of CD89 activating molecules, in particular Fc alpha comprising molecules, and more particularly, IgA, for inducing apoptosis in neutrophils. Anti-CD89 antibodies can alternatively be used. The CD89 activation is beneficial in the treatment of various disorders associated with increases in neutrophils, such as autoimmune disorders, inflammatory disorders, NETosis, or cystic fibrosis.
    Type: Application
    Filed: December 19, 2016
    Publication date: June 15, 2017
    Applicants: CSL BEHRING AG, UNIVERSITÄT BERN
    Inventors: Stephan VON GUNTEN, Marc WEHRLI, Adrian ZÜRCHER, Sylvia MIESCHER
  • Treatment of mucositis with immunoglobulin
    Patent number: 9546209
    Abstract: The invention relates to compositions comprising immunoglobulin for use in the treatment of mucositis by topical application. In particular, the invention relates to compositions comprising J chain-containing IgA and secretory component for the treatment of mucositis.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: January 17, 2017
    Assignees: CSL Behring AG, Universitaet Bern
    Inventors: Christoph Aebi, Sonja Christina Lueer, Alexander Schaub, Sylvia Miescher, Adrian Zuercher, Cédric Pierre Vonarburg
  • CD89 activation in therapy
    Patent number: 9522184
    Abstract: The invention relates to the use of CD89 activating molecules, in particular Fc alpha comprising molecules, and more particularly, IgA, for inducing apoptosis in neutrophils. Anti-CD89 antibodies can alternatively be used. The CD89 activation is beneficial in the treatment of various disorders associated with increases in neutrophils, such as autoimmune disorders, inflammatory disorders, NETosis, or cystic fibrosis.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: December 20, 2016
    Assignees: CSL BEHRING AG, UNIVERSITAT BERN
    Inventors: Stephan Von Gunten, Marc Wehrli, Adrian Zürcher, Sylvia Miescher
  • Nutritional composition comprising strains and reducing food allergy symptoms, especially in infants and children
    Patent number: 9439449
    Abstract: A complete nutritional composition comprising Bifidobacterium strains or probiotic is provided for reducing the symptoms of allergies originating from food allergens in young children or infants. Preferably the composition reduces symptoms of allergies (secondary prevention) and also reduces sensitization (primary prevention). The composition comprises a probiotic of the genus Bifidobacterium.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: September 13, 2016
    Assignee: Nestec S.A.
    Inventors: Sebastien Holvoet, Annick Mercenier, Adrian Zuercher
  • Prevention of allergy at weaning
    Patent number: 9226945
    Abstract: A nutritional composition comprising a partially hydrolyzed milk protein having a degree of hydrolysis between 15 and 25% and 50 to 1000 nanograms of TGF-? per 100 ml of ready to consume composition and methods for the primary prevention of allergic reactions to newly introduced dietary protein at weaning and the prevention of development of atopic diseases in a young mammal at weaning comprising feeding to the young mammal a therapeutic amount of the composition are disclosed.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: January 5, 2016
    Assignee: Nestec S.A.
    Inventors: Annick Mercenier, Marie-Claire Fichot, Adrian Zuercher
  • Nutritional composition comprising strains and reducing allergy symptoms, especially in infants and children
    Patent number: 9049881
    Abstract: A complete nutritional composition comprising Lactococcus strains or probiotic is provided for reducing the symptoms of allergies in different groups of patients such as allergies originating from food allergens in young children or infants and respiratory allergens in children, adults and household pets. Preferably the composition reduces symptoms of allergies (secondary prevention) while not significantly affecting sensitization (primary prevention). The composition comprises a probiotic of the genus Lactococcus.
    Type: Grant
    Filed: August 13, 2010
    Date of Patent: June 9, 2015
    Assignee: Nestec S.A.
    Inventors: Sebastien Holvoet, Annick Mercenier, Adrian Zuercher, Anurag Singh
  • COMPOSITIONS COMPRISING SECRETORY - LIKE IMUNOGLOBULINS
    Publication number: 20150056180
    Abstract: The invention relates to methods for preparing compositions comprising secretory-like immunoglobulin, in particular secretory-like IgA and/or secretory-like IgM, and compositions obtainable by the methods.
    Type: Application
    Filed: March 8, 2013
    Publication date: February 26, 2015
    Inventors: Blaise Corthésy, Stéphanie Longet, Marius Lötscher, Sylvia Miescher, Adrian Zürcher
  • TREATMENT OF MUCOSITIS WITH IMMUNOGLOBULIN
    Publication number: 20150030613
    Abstract: The invention relates to compositions comprising immunoglobulin for use in the treatment of mucositis by topical application. In particular, the invention relates to compositions comprising J chain-containing IgA and secretory component for the treatment of mucositis.
    Type: Application
    Filed: March 8, 2013
    Publication date: January 29, 2015
    Inventors: Christoph Aebi, Sonja Christina Lueer, Alexander Schaub, Sylvia Miescher, Adrian Zürcher, Cédric Pierre Vonarburg
  • PREVENTION OF INFECTION
    Publication number: 20150017181
    Abstract: The invention relates to compositions and methods to prevent enteric infection in a subject at risk of such infection. In particular, the invention relates to the prevention of recurrence of infection by Clostridium difficile.
    Type: Application
    Filed: March 8, 2013
    Publication date: January 15, 2015
    Applicants: BETH ISRAEL DEACONESS MEDICAL CENTER INC, CSL BEHRING AG
    Inventors: Ciaran Kelly, Xinhua Chen, Sylvia Miescher, Martin Spycher, Sandra Wymann, Adrian Zuercher
  • Nutritional composition comprising an apple extract and reducing food allergy symptoms, especially in children
    Patent number: 8911803
    Abstract: A complete nutritional composition comprising polyphenols is provided for reducing the symptoms of allergies originating from food allergens in young children or infants. Preferably the composition modulates the secondary prevention of allergies while not affecting significantly the primary prevention. The composition comprises an apple extract.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: December 16, 2014
    Assignee: Nestec S.A.
    Inventors: Sebastien Holvoet, Annick Mercenier, Adrian Zuercher
  • CD89 ACTIVATION IN THERAPY
    Publication number: 20130302345
    Abstract: The invention relates to the use of CD89 activating molecules, in particular Fc alpha comprising molecules, and more particularly, IgA, for inducing apoptosis in neutrophils. Anti-CD89 antibodies can alternatively be used. The CD89 activation is beneficial in the treatment of various disorders associated with increases in neutrophils, such as autoimmune disorders, inflammatory disorders, NETosis, or cystic fibrosis.
    Type: Application
    Filed: December 14, 2011
    Publication date: November 14, 2013
    Applicants: UNIVERSITÄT BERN, CSL BEHRING AG
    Inventors: Stephan Von Gunten, Marc Wehrli, Adrian Zürcher, Sylvia Miescher
  • Prevention of allergy at weaning
    Patent number: 8383587
    Abstract: A nutritional composition comprising a partially hydrolysed milk protein having a degree of hydrolysis between 15 and 25% and 50 to 1000 nanograms of TGF-? per 100 ml of ready to consume composition and methods for the primary prevention of allergic reactions to newly introduced dietary protein at weaning and the prevention of development of atopic diseases in a young mammal at weaning comprising feeding to the young mammal a therapeutic amount of the composition are disclosed.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: February 26, 2013
    Assignee: Nectec S.A.
    Inventors: Annick Mercenier, Marie-Claire Fichot, Adrian Zuercher
  • NUTRITIONAL COMPOSITION COMPRISING BIFIDOBACTERIUM LONGUM STRAINS AND REDUCING FOOD ALLERGY SYMPTOMS, ESPECIALLY IN INFANTS AND CHILDREN
    Publication number: 20120164109
    Abstract: A complete nutritional composition comprising Bifidobacterium strains or probiotic is provided for reducing the symptoms of allergies originating from food allergens in young children or infants. Preferably the composition reduces symptoms of allergies (secondary prevention) and also reduces sensitization (primary prevention). The composition comprises a probiotic of the genus Bifidobacterium.
    Type: Application
    Filed: August 11, 2010
    Publication date: June 28, 2012
    Applicant: NESTEC S.A.
    Inventors: Sebastien Holvoet, Annick Mercenier, Adrian Zuercher
  • NUTRITIONAL COMPOSITION COMPRISING LACTOCOCCUS STRAINS AND REDUCING ALLERGY SYMPTOMS, ESPECIALLY IN INFANTS AND CHILDREN
    Publication number: 20120148629
    Abstract: A complete nutritional composition comprising Lactococcus strains or probiotic is provided for reducing the symptoms of allergies in different groups of patients such as allergies originating from food allergens in young children or infants and respiratory allergens in children, adults and household pets. Preferably the composition reduces symptoms of allergies (secondary prevention) while not significantly affecting sensitization (primary prevention). The composition comprises a probiotic of the genus Lactococcus.
    Type: Application
    Filed: August 13, 2010
    Publication date: June 14, 2012
    Applicant: NESTEC S.A.
    Inventors: Sebastien Holvoet, Annick Mercenier, Adrian Zuercher, Anurag Singh
  • Human monoclonal antibody specific for lipopolysaccharides (LPS) of the IATS O11 serotype
    Patent number: 8197816
    Abstract: The present invention relates to a human monoclonal antibody specific for the serotype IATS O11 of P. aeruginosa, a hybridoma producing it, nucleic acids encoding it, and host cells transfected therewith. Further, the present invention relates to methods for producing said monoclonal antibody. In addition, the present invention relates to pharmaceutical compositions comprising at least one antibody or at least one nucleic acid encoding said antibody.
    Type: Grant
    Filed: February 13, 2006
    Date of Patent: June 12, 2012
    Assignee: Kenta Biotech AG
    Inventors: Alois B. Lang, Michael P. Horn, Martin A. Imboden, Adrian Zuercher
  • NUTRITIONAL COMPOSITION COMPRISING AN APPLE EXTRACT AND REDUCING FOOD ALLERGY SYMPTOMS, ESPECIALLY IN CHILDREN
    Publication number: 20120021078
    Abstract: A complete nutritional composition comprising polyphenols is provided for reducing the symptoms of allergies originating from food allergens in young children or infants. Preferably the composition modulates the secondary prevention of allergies while not affecting significantly the primary prevention. The composition comprises an apple extract.
    Type: Application
    Filed: April 23, 2010
    Publication date: January 26, 2012
    Applicant: NESTEC S.A.
    Inventors: Sebastien Holvoet, Annick Mercenier, Adrian Zuercher