Patents by Inventor Adriana Botes

Adriana Botes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutant polypeptides and uses thereof
    Patent number: 9220742
    Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.
    Type: Grant
    Filed: July 16, 2015
    Date of Patent: December 29, 2015
    Assignee: INVISTA NORTH AMERICA S.A.R.L.
    Inventors: Adriana Botes, Nadia Kadi, Mihai Luchian Azoitei, Yih-En A Ban, Daniela Grabs-Röthlisberger, Alexander Pisarchik, Alexandre Zanghellini, Eric Althoff
  • Methods For Obtaining Optically Active Epoxides and Vicinal Diols From Styrene Oxides
    Publication number: 20070281339
    Abstract: The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific styrene epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing such vectors. Also embraced by the invention are methods for obtaining optically active styrene vicinal diols and optically active styrene epoxides.
    Type: Application
    Filed: April 18, 2005
    Publication date: December 6, 2007
    Inventors: Adriana Botes, Jeannette Lotter, Michel Labuschagne, Robin Mitra
  • Methods For Obtaining Optically Active Epoxides And Vicinal Diols From Meso-Epoxides
    Publication number: 20070275448
    Abstract: The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific meso-epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing such vectors. Also embraced by the invention are methods for obtaining optically active vicinal diols from meso-epoxides.
    Type: Application
    Filed: April 18, 2005
    Publication date: November 29, 2007
    Applicant: CSIR
    Inventors: Adriana Botes, Jeanette Lotter, Michel Labuschagne