Patents by Inventor Adriana Marie Kruisbeek

Adriana Marie Kruisbeek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic cancer vaccines derived from a novel dendritic cell line
    Patent number: 10064923
    Abstract: The invention is in the field of medical sciences. It provides means and methods for the treatment of cancer. More in particular, it provides cells and cell lines that can be developed into fully functional dendritic cells. These cells endogenously express cancer-specific antigens, which makes them particularly suited for the treatment of different kinds of cancer. More in particular, the invention relates to a precursor cell line for dendritic cells called DC-One as deposited at the DSMZ under accession number DSMZ ACC3189 on Nov. 15, 2012.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: September 4, 2018
    Assignee: DCPRIME B.V.
    Inventors: Sandra Van Wetering, Adriana Marie Kruisbeek
  • THERAPEUTIC CANCER VACCINES DERIVED FROM A NOVEL DENDRITIC CELL LINE
    Publication number: 20150297698
    Abstract: The invention is in the field of medical sciences. It provides means and methods for the treatment of cancer. More in particular, it provides cells and cell lines that can be developed into fully functional dendritic cells. These cells endogenously express cancer-specific antigens, which makes them particularly suited for the treatment of different kinds of cancer. More in particular, the invention relates to a precursor cell line for dendritic cells called DC-One as deposited at the DSMZ under accession number DSMZ ACC3189 on Nov. 15, 2012.
    Type: Application
    Filed: December 10, 2013
    Publication date: October 22, 2015
    Applicant: DCPRIME B.V.
    Inventors: Sandra Van Wetering, Adriana Marie Kruisbeek
  • METHOD FOR LOADING OF DENDRITIC CELLS WITH CLASS I ANTIGENS
    Publication number: 20150166955
    Abstract: Disclosed is a method to obtain dendritic cells loaded with an exogenously added antigen. The method is in particular applicable to human cell lines that may be used in the production of dendritic cell vaccines, e.g. to be used in the treatment of cancer. In the method the antigen to be loaded on the cells is added to the cells at particular stages of the development of the dendritic cells. A pharmaceutical composition comprising the obtained cells is also disclosed.
    Type: Application
    Filed: July 2, 2013
    Publication date: June 18, 2015
    Inventors: Sandra Van Wetering, Adriana Marie Kruisbeek