Patents by Inventor Adrianus Johannes Christiaan van den Brule

Adrianus Johannes Christiaan van den Brule has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligonucleotides for the amplification and detection of Epstein Barr Virus (EBV) nucleic acid
    Patent number: 7026112
    Abstract: The present invention is concerned with oligonucleotides that can be used as in the amplification and detection of Epstein Barr Virus (EBV) nucleic acid, in particular RNA-specific sequences. Furthermore a method for the diagnosis of EBV associated malignant and non-malignant diseases is provided. The oligonucleotides according to the present invention are specifically suited for the detection of EBV gene expression in circulating peripheral blood cells, in human (tumor) tissue samples and thin sections thereof using “in solution” amplification or “in situ” amplification techniques and in other biological samples potentially containing EBV-infected cells.
    Type: Grant
    Filed: March 1, 1999
    Date of Patent: April 11, 2006
    Assignee: Akzo Nobel N.V.
    Inventors: Marcel Bartolina Hendrikus Johannes Vervoort, Adrianus Johannes Christiaan van den Brule, Jaap Michiel Middeldorp