Patents by Inventor Adrianus van den Hoogenband

Adrianus van den Hoogenband has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hexa- and octahydro-pyrido[1,2-a]pyrazine derivatives with NKantagonistic activity
    Patent number: 7244734
    Abstract: The invention relates to hexahydro-pyrido[1,2-a]pyrazine derivatives having interesting neurokinin-NK1 receptor antagonistic activity. The invention also relates to methods for the preparation of these compounds, to pharmaceutical compositions containing a pharmacologically active amount of at least one of these compounds as an active ingredient, as well as to the use of these compositions for the treatment of disorders in which neurokinin receptors are involved. The invention relates to compounds represented by the general formula (1) wherein the symbols have the meanings as given in the description.
    Type: Grant
    Filed: September 22, 2004
    Date of Patent: July 17, 2007
    Assignee: Solvay Pharmaceuticals B.V.
    Inventors: Wouter I. Iwema Bakker, Gustaaf J. M. Van Scharrenburg, Adrianus Van Den Hoogenband, Andrew C. McCreary
  • Piperazine oxime dervatives having NK-1 receptor antagonistic activity
    Patent number: 7094779
    Abstract: The present invention relates to a group of novel piperazine oxime derivatives having interesting NK-1 antagonistic activity.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: August 22, 2006
    Assignee: Solvay Pharmaceuticals B.V.
    Inventors: Wouter I. Iwema Bakker, Jan H. van Maarseveen, Hein K. A. C. Coolen, Martinus Th. M. Tulp, Arnoldus H. J. Herremans, Andrew C. Mccreary, Gustaaf J. M. van Scharrenburg, Adrianus van den Hoogenband
  • Hexa-and octahydro-pyrido[1,2-a]pyrazine derivatives with NK1 antagonistic activity
    Publication number: 20050070548
    Abstract: The invention relates to hexahydro-pyrido[1,2-a]pyrazine derivatives having interesting neurokinin-NK1 receptor antagonistic activity. The invention also relates to methods for the preparation of these compounds, to pharmaceutical compositions containing a pharmacologically active amount of at least one of these compounds as an active ingredient, as well as to the use of these compositions for the treatment of disorders in which neurokinin receptors are involved. The invention relates to compounds represented by the general formula (1) wherein the symbols have the meanings as given in the description.
    Type: Application
    Filed: September 22, 2004
    Publication date: March 31, 2005
    Inventors: Wouter Iwema Bakker, Gustaaf Van Scharrenburg, Adrianus Van Den Hoogenband, Andrew McCreary
  • Piperazine oxime dervatives having nk-1 receptor antagonistic activity
    Publication number: 20040176389
    Abstract: The present invention relates to a group of novel piperazine oxime derivatives having interesting NK-1 antagonistic activity.
    Type: Application
    Filed: December 12, 2003
    Publication date: September 9, 2004
    Inventors: Wouter I Ivema Bakker, Jan H van Maarseveen, Hein K A C Coolen, Martinus Th M Tulp, Arnoldus H J Herremans, Andrew C Mccreary, Gustaaf J M van Scharrenburg, Adrianus van den Hoogenband