Patents by Inventor Adrien CERDAN

Adrien CERDAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL DPP1 INHIBITORS AND USES THEREOF
    Publication number: 20260062420
    Abstract: Provided herein are novel DPP1 inhibitor compounds having the general structure of Formula (I), (II) or (III), or a pharmaceutically acceptable salt thereof. Also provided are certain methods of treatment, e.g., a method for treating an obstructive disease of the airway or a method of treating an inflammatory condition with a composition comprising an effective amount of one of the compounds provided herein.
    Type: Application
    Filed: July 27, 2023
    Publication date: March 5, 2026
    Inventors: Adam J. PLAUNT, David C. CIPOLLA, Adrien CERDAN, Paola CIAPETTI, Bastien GOEGAN, David J. AUGERI
  • NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF
    Publication number: 20260055093
    Abstract: Provided herein are compounds of Formula (I), or pharmaceutically acceptable salts or deuterated forms thereof, wherein R0, L and R1 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) or pharmaceutically acceptable salt or deuterated form thereof, and methods of using a compound of Formula (I) or pharmaceutically acceptable salt or deuterated form thereof, e.g., in the treatment of a disease that is treatable by administration of a DPP1 inhibitor.
    Type: Application
    Filed: August 28, 2025
    Publication date: February 26, 2026
    Inventors: Adam J. PLAUNT, Adrien CERDAN, Paola CIAPETTI, Bastien GOEGAN
  • Reversible DPP1 inhibitors and uses thereof
    Patent number: 12479837
    Abstract: Provided herein are compounds of Formula (I), or pharmaceutically acceptable salts or deuterated forms thereof, wherein R0, L and R1 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) or pharmaceutically acceptable salt or deuterated form thereof, and methods of using a compound of Formula (I) or pharmaceutically acceptable salt or deuterated form thereof, e.g., in the treatment of a disease that is treatable by administration of a DPP1 inhibitor.
    Type: Grant
    Filed: March 24, 2025
    Date of Patent: November 25, 2025
    Assignee: Insmed Incorporated
    Inventors: Adam J. Plaunt, Adrien Cerdan, Paola Ciapetti, Bastien Goegan
  • REVERSIBLE DPP1 INHIBITORS AND USES THEREOF
    Publication number: 20250223284
    Abstract: Provided herein are compounds of Formula (I), or pharmaceutically acceptable salts or deuterated forms thereof, wherein R0, L and R1 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) or pharmaceutically acceptable salt or deuterated form thereof, and methods of using a compound of Formula (I) or pharmaceutically acceptable salt or deuterated form thereof, e.g., in the treatment of a disease that is treatable by administration of a DPP1 inhibitor.
    Type: Application
    Filed: March 24, 2025
    Publication date: July 10, 2025
    Inventors: Adam J. PLAUNT, Adrien CERDAN, Paola CIAPETTI, Bastien GOEGAN