Patents by Inventor Adrien E. Desjardins
Adrien E. Desjardins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11647957Abstract: Provided herein is a probe for ultrasound imaging of tissue. The probe comprises an optical relay having an optically absorbing coating at the distal end of the probe for generating ultrasound from excitation light via the photoacoustic effect, wherein the generated ultrasound propagates as an ultrasound beam into the tissue; and an ultrasound receiver separate from the optical relay. The optical relay is configured to receive as input a time-varying spatial pattern of excitation light at the proximal end of the probe and to transmit the excitation light to the distal end of the probe to illuminate the optically absorbing coating in accordance with said time-varying spatial pattern, thereby generating ultrasound from the excitation light via the photoacoustic effect to propagate as a scanning ultrasound beam into the tissue. The ultrasound receiver is configured to receive reflections of the ultrasound from tissue. Such an ultrasound probe may be incorporated, for example, into a transseptal puncture needle.Type: GrantFiled: January 8, 2016Date of Patent: May 16, 2023Assignee: UCL BUSINESS LTDInventors: Adrien E. Desjardins, Edward Zhiyi Zhang, Malcolm Finlay, Paul Beard, Ioannis Papakonstantinou
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Publication number: 20180028117Abstract: Provided herein is a probe for ultrasound imaging of tissue. The probe comprises an optical relay having an optically absorbing coating at the distal end of the probe for generating ultrasound from excitation light via the photoacoustic effect, wherein the generated ultrasound propagates as an ultrasound beam into the tissue; and an ultrasound receiver separate from the optical relay. The optical relay is configured to receive as input a time-varying spatial pattern of excitation light at the proximal end of the probe and to transmit the excitation light to the distal end of the probe to illuminate the optically absorbing coating in accordance with said time-varying spatial pattern, thereby generating ultrasound from the excitation light via the photoacoustic effect to propagate as a scanning ultrasound beam into the tissue. The ultrasound receiver is configured to receive reflections of the ultrasound from tissue. Such an ultrasound probe may be incorporated, for example, into a transseptal puncture needle.Type: ApplicationFiled: January 8, 2016Publication date: February 1, 2018Applicant: UCL Business PLCInventors: Adrien E. Desjardins, Edward Zhiyi Zhang, Malcolm Finlay, Paul Beard, Ioannis Papakonstantinou
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Patent number: 8977343Abstract: An optical probe and an optical imaging system include an optical guide, and an actuator having driving coils and a magnet. By supplying a driving current through the driving a magnetic flux is generated which causes a displacement of the distal end of the optical guide. A position measuring device includes a position measuring coil used for monitoring the position of the optical guide, where displacement of the guide distal end causes change in the relative positions of the measuring and driving coils. A power supply supplies a high frequency AC current through the driving coils which causes, an induced voltage in the position measuring coil and thus generates a magnetic coupling between the measuring and driving coils. This induced voltage change is indicative for the position of the distal end.Type: GrantFiled: October 21, 2009Date of Patent: March 10, 2015Assignee: Koninklijke Philips N.V.Inventors: Cornelius A. Hezemans, Bernardus H. W. Hendriks, Waltherus C. J. Bierhoff, Augustinus L. Braun, Adrien E. Desjardins
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Patent number: 8108032Abstract: An optical coherent tomography diagnostic apparatus including: a light source; a splitter for splitting the light outputted from the light source into a measuring light and a reference light; a measuring light path; a reference light path; a probe inserted into a body cavity and emitting the measuring light to a subject of measurement; an image forming unit for calculating intensity distribution of the reflection light and for forming a tomographic image; a standard light path for transmitting standard light obtained by further splitting the light; wherein the light path length when exerting interference between the standard light and the reference light is approximately equal to the light path length when exerting interference between the reference light and the reflection light, and there is included a calculation unit for calculating time change of coherent light data obtained by exerting interference between the standard light and the reference light.Type: GrantFiled: November 20, 2008Date of Patent: January 31, 2012Assignee: Terumo Kabushiki KaishaInventors: Yuuji Onimura, Adrien E. Desjardins
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Publication number: 20110201922Abstract: This invention relates to an optical probe (200) and an optical imaging system, including an optical guide (201) having a proximal end and a distal end, an actuation means having driving coils (204) and a magnet, with of which being attached to the optical guide. By supplying a driving current through the driving coils a magnetic flux is generated which interacts with the magnet forming a driving force acting at on the optical guide causing a displacement of the distal end of the optical guide. A position measuring including a position measuring coil (205) is used for monitoring the position of the optical guide, where the internal arrangement of the position measuring coil and the driving coils is such that said displacement of the distal end of the optical guide causes a change in the internal arrangement.Type: ApplicationFiled: October 21, 2009Publication date: August 18, 2011Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Cornelis A. Hezemans, Bernardus H.W. Hendriks, Waltherus C.J. Bierhoff, Augustinus L. Braun, Adrien E. Desjardins
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Patent number: 7982879Abstract: Arrangements, apparatus and methods are provided according to exemplary embodiments of the present invention. In particular, at least one first electro-magnetic radiation may be received and at least one second electro-magnetic radiation within a solid angle may be forwarded to a sample. The second electro-magnetic radiation may be associated with the first electro-magnetic radiation. A plurality of third electro-magnetic radiations can be received from the sample which is associated with the second electro-magnetic radiation, and at least one portion of the third electro-magnetic radiation is provided outside a periphery of the solid angle. Signals associated with each of the third electro-magnetic radiations can be simultaneously detected, with the signals being associated with information for the sample at a plurality of depths thereof. The depths can be determined using at least one of the third electro-magnetic radiations without a need to utilize another one of the third electro-magnetic radiations.Type: GrantFiled: February 21, 2007Date of Patent: July 19, 2011Assignee: The General Hospital CorporationInventors: Adrien E. Desjardins, Benjamin J. Vakoc, Guillermo J. Tearney, Brett Eugene Bouma
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Publication number: 20090143686Abstract: An optical coherent tomography diagnostic apparatus including: a light source; a splitter for splitting the light outputted from the light source into a measuring light and a reference light; a measuring light path; a reference light path; a probe inserted into a body cavity and emitting the measuring light to a subject of measurement; an image forming unit for calculating intensity distribution of the reflection light and for forming a tomographic image; a standard light path for transmitting standard light obtained by further splitting the light; wherein the light path length when exerting interference between the standard light and the reference light is approximately equal to the light path length when exerting interference between the reference light and the reflection light, and there is included a calculation unit for calculating time change of coherent light data obtained by exerting interference between the standard light and the reference light.Type: ApplicationFiled: November 20, 2008Publication date: June 4, 2009Applicant: TERUMO KABUSHIKI KAISHAInventors: Yuuji ONIMURA, Adrien E. Desjardins
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Publication number: 20070201033Abstract: Arrangements, apparatus and methods are provided according to exemplary embodiments of the present invention. In particular, at least one first electro-magnetic radiation may be received and at least one second electro-magnetic radiation within a solid angle may be forwarded to a sample. The second electro-magnetic radiation may be associated with the first electro-magnetic radiation. A plurality of third electro-magnetic radiations can be received from the sample which is associated with the second electro-magnetic radiation, and at least one portion of the third electro-magnetic radiation is provided outside a periphery of the solid angle. Signals associated with each of the third electro-magnetic radiations can be simultaneously detected, with the signals being associated with information for the sample at a plurality of depths thereof. The depths can be determined using at least one of the third electro-magnetic radiations without a need to utilize another one of the third electro-magnetic radiations.Type: ApplicationFiled: February 21, 2007Publication date: August 30, 2007Applicant: The General Hospital CorporationInventors: Adrien E. Desjardins, Benjamin J. Vakoc, Guillermo J. Tearney, Brett Eugene Bouma