Abstract: The invention relates to a lateral flow device (10) for taking at least one analyte of interest in a fluid, comprising: a fluid receiving zone (100) for receiving the fluid, comprising a first absorbent material (111) that is capable of collecting the fluid; at least one zone of migration (201) for migration of the fluid, extending between a first end and a second end, each zone of migration including a draining material (211) in fluid continuity with the first absorbent material; at least one fluid reservoir (storage) zone (301) comprising a second absorbent material (311) in contact with the draining material at the level of the second end of each fluid migration zone; the detection means between the receiving zone and the reservoir zone, that provide the ability to determine the presence or absence of the said one or more analyte(s) of interest in the sample; characterised in that at least the one of the said zones of migration further also comprises at least one capture zone (400) that is capable of re

Abstract: The invention is a method for capturing biological species present in a body tissue. The method comprises an arrangement of tissue on a support, referred to as a capture support, capable of selectively capturing one or more biological species, referred to as species of interest. The method comprises; —a step of depositing a lysis reagent on the tissue; —a step of droplet formation, on the surface of the tissue, each droplet comprising the solubilized lysis reagent; —a formation of lysis sites, in the tissue, between each droplet and the capture support, such that at each lysis site, species of interest are freed and captured by the capture support.

Abstract: The invention is a method for capturing biological species present in a body tissue. The method comprises an arrangement of tissue on a support, referred to as a capture support, capable of selectively capturing one or more biological species, referred to as species of interest. The method comprises; a step of depositing a lysis reagent on the tissue; a step of droplet formation, on the surface of the tissue, each droplet comprising the solubilized lysis reagent; a formation of lysis sites, in the tissue, between each droplet and the capture support, such that at each lysis site, species of interest are freed and captured by the capture support.

Abstract: The invention relates to a device (100) for sampling a biological tissue comprising: a rod (1) extending along a longitudinal axis (X) between a proximal end (1a) and a distal end (1b), a capture surface (2) borne by the rod (1), intended to be applied against a biological tissue, wherein the capture surface is nanoporous or has protrusions adapted for sampling a biological tissue by micro abrasion, an observation window (3) transparent to visible light, laid out in the external surface of the rod (1), a housing (4) extending in the rod, parallel to the longitudinal axis, from the proximal end (1a) as far as the observation window (3) said housing being able to receive a bundle of optical fibers.

Abstract: The invention relates to a device for in vivo sampling of biological species, comprising:—a capture medium made from a nanoporous material, having a capture surface for said species, said capture medium being supported by a plate,—a gripping rod,—an articulation comprising a first limb coupled to the gripping rod and a second limb coupled removably to the plate supporting the capture medium, such that the capture surface can be selectively oriented relative to the gripping rod, so as to adjust the orientation of the capture medium relative to the gripping rod.

Abstract: The invention relates to a lateral flow device (10) for taking at least one analyte of interest in a fluid, comprising: a fluid receiving zone (100) for receiving the fluid, comprising a first absorbent material (111) that is capable of collecting the fluid; at least one zone of migration (201) for migration of the fluid, extending between a first end and a second end, each zone of migration including a draining material (211) in fluid continuity with the first absorbent material; at least one fluid reservoir (storage) zone (301) comprising a second absorbent material (311) in contact with the draining material at the level of the second end of each fluid migration zone; the detection means between the receiving zone and the reservoir zone, that provide the ability to determine the presence or absence of the said one or more analyte(s) of interest in the sample; characterised in that at least the one of the said zones of migration further also comprises at least one capture zone (400) that is capable of re

Abstract: The invention relates to a device for in vivo sampling of biological species, comprising: a tubular sheath extending between a proximal end of said sheath and a distal end of said sheath, said distal end of the sheath having a projecting part, a rod extending between a proximal end of said rod and a distal end of said rod, capable of sliding in the sheath between a retracted position in which the distal end of the rod is located inside the sheath and a deployed position in which the distal end of the rod extends beyond the distal end of the sheath, said rod comprising a capturing support for capturing said biological species, made from a porous material, arranged in a distal region of the rod on a portion of the circumference of the rod such that the capturing support is located outside the sheath when the rod is in the deployed position of same.

Abstract: The invention relates to a device for in vivo sampling of biological species, comprising:—a capture medium made from a nanoporous material, having a capture surface for said species, said capture medium being supported by a plate,—a gripping rod,—an articulation comprising a first limb coupled to the gripping rod and a second limb coupled removably to the plate supporting the capture medium, such that the capture surface can be selectively oriented relative to the gripping rod, so as to adjust the orientation of the capture medium relative to the gripping rod.

Abstract: The invention relates to a device (100) for sampling a biological tissue comprising: a rod (1) extending along a longitudinal axis (X) between a proximal end (1a) and a distal end (1b), a capture surface (2) borne by the rod (1), intended to be applied against a biological tissue, wherein the capture surface is nanoporous or has protrusions adapted for sampling a biological tissue by micro abrasion, an observation window (3) transparent to visible light, laid out in the external surface of the rod (1), a housing (4) extending in the rod, parallel to the longitudinal axis, from the proximal end (1a) as far as the observation window (3) said housing being able to receive a bundle of optical fibers.