Patents by Inventor Adrien Nivoliez

Adrien Nivoliez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11730777
    Abstract: The disclosure relates to a mucoadhesive sustained-release vaginal tablet including at least one probiotic strain of the genus Lactobacillus compressed with an excipient suitable for conferring upon the tablet the properties of vaginal wall mucoadhesion and sustained release.
    Type: Grant
    Filed: June 25, 2019
    Date of Patent: August 22, 2023
    Assignee: NEXBIOME THERAPEUTICS
    Inventors: Claudia Thoral, Pierre Tchoreloff, Vincent Mazel, Virginie Busignies, Adrien Nivoliez
  • Publication number: 20220125863
    Abstract: The present invention relates to a composition comprising as antifungal active agent at least 2·1010 CFU of lactobacilli and a sulfur-containing compound for use as a first-line treatment for candidiasis and for recurrent candidiasis.
    Type: Application
    Filed: November 10, 2021
    Publication date: April 28, 2022
    Inventor: Adrien NIVOLIEZ
  • Publication number: 20220062330
    Abstract: The present invention relates to the use of thiosulfate to potentiate the anti pathogenic effect of Lactobacilli bacteria, the thiosulfate being in a quantity of at least 100 mg for 107 to 1010 CFU of Lactobacilli. The invention also relates to a pharmaceutical composition including at least 100 mg of thiosulfate per gram, in combination with a Lactobacillus crispatus strain, and to its use in the treatment of urogenital infections such as vaginosis, candidosis and urinary tract infections.
    Type: Application
    Filed: November 11, 2021
    Publication date: March 3, 2022
    Inventor: Adrien NIVOLIEZ
  • Patent number: 11202799
    Abstract: The present invention relates to the use of thiosulfate to potentiate the anti-pathogenic effect of lactobacilli bacteria, the thiosulfate being in a quantity of at least 100 mg for 107 to 1010 CFU of lactobacilli. The invention also relates to a pharmaceutical composition including at least 100 mg of thiosulfate per gram, in combination with a Lactobacillus crispatus strain, and to its use in the treatment of urogenital infections such as vaginosis, candidosis and urinary tract infections.
    Type: Grant
    Filed: February 19, 2018
    Date of Patent: December 21, 2021
    Assignee: PROBIONOV
    Inventor: Adrien Nivoliez
  • Patent number: 11197899
    Abstract: The present invention relates to a composition comprising as antifungal active agent at least 2·1010 CFU of lactobacilli and a sulfur-containing compound for use as a first-line treatment for candidiasis and for recurrent candidiasis.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: December 14, 2021
    Assignee: NEXBIOME THERAPEUTICS
    Inventor: Adrien Nivoliez
  • Publication number: 20200155621
    Abstract: The disclosure relates to a mucoadhesive sustained-release vaginal tablet including at least one probiotic strain of the genus Lactobacillus compressed with an excipient suitable for conferring upon the tablet the properties of vaginal wall mucoadhesion and sustained release.
    Type: Application
    Filed: June 25, 2019
    Publication date: May 21, 2020
    Inventors: Claudia THORAL, Pierre TCHORELOFF, Vincent MAZEL, Virginie BUSIGNIES, Adrien NIVOLIEZ
  • Publication number: 20190046593
    Abstract: The present invention relates to a composition comprising as antifungal active agent at least 2·1010 CFU of lactobacilli and a sulfur-containing compound for use as a first-line treatment for candidiasis and for recurrent candidiasis.
    Type: Application
    Filed: March 1, 2017
    Publication date: February 14, 2019
    Inventor: Adrien NIVOLIEZ
  • Publication number: 20180360874
    Abstract: The present invention relates to the use of thiosulfate to potentiate the anti-pathogenic effect of lactobacilli bacteria, the thiosulfate being in a quantity of at least 100 mg for 107 to 1010 CFU of lactobacilli. The invention also relates to a pharmaceutical composition including at least 100 mg of thiosulfate per gram, in combination with a Lactobacillus crispatus strain, and to its use in the treatment of urogenital infections such as vaginosis, candidosis and urinary tract infections.
    Type: Application
    Filed: February 19, 2018
    Publication date: December 20, 2018
    Inventor: Adrien NIVOLIEZ
  • Publication number: 20170014458
    Abstract: The disclosure relates to a mucoadhesive sustained-release vaginal tablet including at least one probiotic strain of the genus Lactobacillus compressed with an excipient suitable for conferring upon the tablet the properties of vaginal wall mucoadhesion and sustained release.
    Type: Application
    Filed: March 10, 2015
    Publication date: January 19, 2017
    Applicant: BIOSE
    Inventors: Claudia THORAL, Pierre TCHORELOFF, Vincent MAZEL, Virginie BUSIGNIES, Adrien NIVOLIEZ
  • Publication number: 20150190438
    Abstract: The disclosure relates to an isolated strain of Lactobacillus crispatus, identified as IP174178 and deposited at the CNCM under number 1-464 or an isolated strain having the same characteristics as IP174178. The disclosure also relates to a pharmaceutical composition or a nutraceutical composition including such a strain, and to the use thereof for the treatment or prevention of genital infections.
    Type: Application
    Filed: July 9, 2013
    Publication date: July 9, 2015
    Applicant: S.P.M.D.
    Inventor: Adrien Nivoliez
  • Publication number: 20150139969
    Abstract: The present disclosure relates to the use of thiosulfate to potentiate the anti-pathogenic effect of lactobacilli bacteria, the thiosulfate being in a quantity of at least 100 mg for 107 to 1010 CFU of lactobacilli. The disclosure also relates to a pharmaceutical composition including at least 100 mg of thiosulfate per gram, in combination with a Lactobacillus crispatus strain, and to its use in the treatment of urogenital infections such as vaginosis, candidosis and urinary tract infections.
    Type: Application
    Filed: July 9, 2013
    Publication date: May 21, 2015
    Applicant: PROBIONOV
    Inventor: Adrien Nivoliez