Abstract: The invention relates to an automatic dispenser (100) of fluid products contained in cartridges, these being able to accommodate a large number of large-capacity cartridges while having reduced over-inking. The dispenser comprises: a frame provided with N slots (E) for cartridges (200A, 200B, 200C) of products, these cartridges being each provided with a reservoir and with a metering pump; an actuation system (30) for the cartridges, comprising: a motor (31) that is able to generate a force for actuating the metering pump of the cartridges; a selective transmission mechanism (32) that is able to selectively transmit the force generated by the motor to at least one of the metering pumps; a recess for a removable container; the N slots (E) being arranged substantially horizontally and in a stepped manner.

Abstract: The invention relates to a secure system for dispensing customised mixtures to different users, the system being capable of regularly collecting qualified data on the user and on previously mixed dispensed doses to enable the mixture to be adapted to changes in one or more specific parameters of the user. The system comprises a remote server comprising a remote central unit (31) associated with a remote database (32), at least one remote interface (40) for an expert (41), and at least one local automatic dispenser capable of dispensing a customised mixture of products, the dispenser comprising a local data display and data collection interface, and a transmitter/receiver capable of communicating with the remote database.

Abstract: A microfluidic thermalization chip, a system using such a chip and a PCR method for detecting DNA sequences. The chip contains a block of material in which a cavity is configured to contain at least one fluid. The cavity includes at least one inlet orifice and at least one outlet orifice. The inlet orifice for the fluid is connected to at least one, preferably at least two, fluid-injecting channels. Further, the chip includes at least one microfluidic channel for bypassing the cavity. The channel is connected by a first end to at least one of the fluid-injecting channels. The junction between the bypassing channel and the fluid-injecting channel is located at a distance L from the inlet orifice of the fluid-injecting channel. The distance L is preferably smaller than 2 cm.

Abstract: A preparation and dispensing system prepares and dispenses a personalized composition from N reserves (501-502) of active compounds (A1-A2), N being an integer greater than or equal to 1, which is accurate, quick, easy to implement, hygienic and economical. The system comprises a pneumatic-pressure generator (200) connected to a pressure distributor (300) comprising N pressure changeover switches (301-306), each one having at least one inlet (I1) connected to the pressure generator, one inlet (I2) connected to atmospheric pressure and an outlet (311-316) connected to an inlet of a reserve of active compound.

Abstract: A microfluidic thermalization chip, a system using such a chip and a PCR method for detecting DNA sequences. The chip contains a block of material in which a cavity is configured to contain at least one fluid. The cavity includes at least one inlet orifice and at least one outlet orifice. The inlet orifice for the fluid is connected to at least one, preferably at least two, fluid-injecting channels. Further, the chip includes at least one microfluidic channel for bypassing the cavity. The channel is connected by a first end to at least one of the fluid-injecting channels. The junction between the bypassing channel and the fluid-injecting channel is located at a distance L from the inlet orifice of the fluid-injecting channel. The distance L is preferably smaller than 2 cm.

Abstract: A micro-structured substrate to support a liquid sample having a lower face and an upper face. At least one surface cavity of volume V0 opening onto the upper face and forming a zone for analyzing the liquid sample. A first groove having a first volume V1, positioned around each surface cavity and opening onto the upper face thereof. The substrate also includes at least one second groove opening onto the upper face thereof and positioned around the first groove. The sum of the volumes of the second grooves is equal to V2. The volume V1+V2 is greater than or equal to 0.05 V0, preferably 0.1 V0. An analysis assembly including the substrate and the use thereof is also contemplated herein.

Abstract: A preparation and dispensing system prepares and dispenses a personalized composition from N reserves (501-502) of active compounds (A1-A2), N being an integer greater than or equal to 1, which is accurate, quick, easy to implement, hygienic and economical. The system comprises a pneumatic-pressure generator (200) connected to a pressure distributor (300) comprising N pressure changeover switches (301-306), each one having at least one inlet (I1) connected to the pressure generator, one inlet (I2) connected to atmospheric pressure and an outlet (311-316) connected to an inlet of a reserve of active compound.

Abstract: A micro-structured substrate to support a liquid sample having a lower face and an upper face. At least one surface cavity of volume V0 opening onto the upper face and forming a zone for analyzing the liquid sample. A first groove having a first volume V1, positioned around each surface cavity and opening onto the upper face thereof. The substrate also includes at least one second groove opening onto the upper face thereof and positioned around the first groove. The sum of the volumes of the second grooves is equal to V2. The volume V1+V2 is greater than or equal to 0.05 V0, preferably 0.1 V0. An analysis assembly including the substrate and the use thereof is also contemplated herein.

Abstract: A microfluidic device for separating, fractionating, or preconcentrating analytes contained in an electrolyte having at least two reservoirs separated by at least one microchannel and/or nanochannel. At least part of the wall of the microchannel is made of and/or coated interiorly with a conducting and polarizable material or group of materials constituting a polarizable interface or a network of polarizable interfaces. In that at least one electrode or at least one electrode network is connected at at least one point of the polarizable material or group of materials, the surface electrical conductance of said material being equal to at least 100 nS.

Abstract: A device for selective preconcentration/detection of charged analytes contained in an electrolyte having at least two reservoirs separated by at least one rectilinear microchannel with no lengthwise axis X intersection and having at least one controllable voltage source configured to generate a potential difference between the ends of the rectilinear microchannel. The device has means for generating a controllable pressure that is associated with at least one of the reservoirs and is able to generate a pressure gradient between the two ends of the microchannel. The microchannel has, in its median part, means that are configured to generate at least one change in the surface area to volume ratio charge, the device configured to selectively concentrate the charged analytes in the median part of the microchannel upstream and/or downstream of the means configured to generate at least one change in the surface area to volume ration charge.

Abstract: A microfluidic device for separating, fractionating, or preconcentrating analytes contained in an electrolyte having at least two reservoirs separated by at least one microchannel and/or nanochannel. At least part of the wall of the microchannel is made of and/or coated interiorly with a conducting and polarizable material or group of materials constituting a polarizable interface or a network of polarizable interfaces. In that at least one electrode or at least one electrode network is connected at least one point of the polarizable material or group of materials, the surface electrical conductance of said material being equal to at least 100 nS.

Abstract: A device for dielectrophoretic separation of particles contained in a fluid, includes two sets of electrodes, each of the two sets of electrodes being brought to a different potential, so as to generate an electric field inside said fluid. The two sets of electrodes are positioned inside a chamber, itself provided with a particle collecting surface. Each of the two sets of electrodes is immersed in the fluid inside the chamber and is located in a plane different from the plane of the particle collecting surface. The two sets of electrodes are supplied with electrical current in phase opposition. The potential of each of the two sets of electrodes have a gradient based on the distance along a direction perpendicular to the plane of the particle collecting surface.

Abstract: A device for selective preconcentration/detection of charged analytes contained in an electrolyte having at least two reservoirs separated by at least one rectilinear microchannel with no lengthwise axis X intersection and having at least one controllable voltage source configured to generate a potential difference between the ends of the rectilinear microchannel. The device has means for generating a controllable pressure that is associated with at least one of the reservoirs and is able to generate a pressure gradient between the two ends of the microchannel. The microchannel has, in its median part, means that are configured to generate at least one change in the surface area to volume ratio charge, the device configured to selectively concentrate the charged analytes in the median part of the microchannel upstream and/or downstream of the means configured to generate at least one change in the surface area to volume ration charge.

Abstract: A device for dielectrophoretic separation of particles contained in a fluid, includes two sets of electrodes, each of the two sets of electrodes being brought to a different potential, so as to generate an electric field inside said fluid. The two sets of electrodes are positioned inside a chamber, itself provided with a particle collecting surface. Each of the two sets of electrodes is immersed in the fluid inside the chamber and is located in a plane different from the plane of the particle collecting surface. The two sets of electrodes are supplied with electrical current in phase opposition. The potential of each of the two sets of electrodes have a gradient based on the distance along a direction perpendicular to the plane of the particle collecting surface.