Abstract: Disclosed herein is the effect that IL-33 has on the tumor microenvironment. In one aspect, disclosed herein are methods for treating a cancer, inhibiting TH2 pro-tumorigenic cytokines in the TME, inhibiting secretion of IL-33 in the TME, and/or inhibiting type 2 immune cell infiltration in the TME by administering of an antifungal agent, a MEK inhibitor, an IL-33 inhibitor, or an ST2 inhibitor, or any combination thereof.

Abstract: There is a modular, insulated, all-in-one, plug-and-play (MIAP) aquaponics unit that includes a framework having a single base and plural walls; an aquaculture tank defined by a first portion of the single base and a first set of the plural walls; a clarifier tank defined by a second portion of the single base and a second set of the plural walls; a bio-reactor tank defined by a third portion of the single base and a third set of the plural walls; a hydroponics tank defined by a fourth portion of the single base and a fourth set of the plural walls; and piping extending through the plural walls between each two adjacent tanks for allowing water from the aquaculture tank to flow into the clarifier tank and then into the bio-reactor tank and then into the hydroponics tank and back to the aquaculture tank.

Abstract: A vertically-stacked growing system includes vertical beams and horizontal shelves respectively arranged on different vertical levels. Each horizontal shelf has a length and a width, and includes horizontal structural supports coupled to at least some of the vertical beams, decking coupled to the horizontal structural supports, and multiple walls to form a shallow pond when the horizontal shelf contains a plant nutrient water culture, thereby constituting a growing layer of the growing system. The walls include two side walls along the length and two end walls along the width. Each horizontal shelf further includes a loading and/or unloading apparatus to facilitate loading and/or unloading of a plurality of rafts into and/or out of the shallow pond, via the two end walls, wherein respective rafts of the plurality of rafts include a plurality of germinated plants.

Abstract: A vertically-stacked growing system includes vertical beams and horizontal shelves respectively arranged on different vertical levels, Each horizontal shelf has a length and a width, and includes horizontal structural supports coupled to at least some of the vertical beams, decking coupled to the horizontal structural supports, and multiple walls to form a shallow pond when the horizontal shelf contains a plant nutrient water culture, thereby constituting a growing layer of the growing system. The walls include two side walls along the length and two end walls along the width. Each horizontal shelf further includes a loading and/or unloading apparatus to facilitate loading and/or unloading of a plurality of rafts into and/or out of the shallow pond, via the two end walls, wherein respective rafts of the plurality of rafts include a plurality of germinated plants.

Abstract: A horticultural raft includes a raft body, at least one top cavity, and a group of mid cavities. The top cavity includes an upper face defining a first projected area and a lower face defining a second projected area substantially equal to or less than the first projected area. The upper face provides a seeding pattern having one or two degrees of freedom in a growing medium disposed in the top cavity. Each mid cavity has an upper face defining a third projected area that is entirely contained within the second projected area. The mid cavities are configured to contribute to buoyancy of the floating horticultural raft, allow germinants in the growing medium to communicate via capillary action with a nutrient solution when the raft is floating in the nutrient solution, and mitigate hyperhydration and asphyxiation at respective root-stem junctions of the germinants.

Abstract: There is a modular, insulated, all-in-one, plug-and-play (MIAP) aquaponics unit that includes a framework having a single base and plural walls; an aquaculture tank defined by a first portion of the single base and a first set of the plural walls; a clarifier tank defined by a second portion of the single base and a second set of the plural walls; a bio-reactor tank defined by a third portion of the single base and a third set of the plural walls; a hydroponics tank defined by a fourth portion of the single base and a fourth set of the plural walls; and piping extending through the plural walls between each two adjacent tanks for allowing water from the aquaculture tank to flow into the clarifier tank and then into the bio-reactor tank and then into the hydroponics tank and back to the aquaculture tank.

Abstract: A horticultural raft includes a raft body, at least one top cavity, and a group of mid cavities. The top cavity includes an upper face defining a first projected area and a lower face defining a second projected area substantially equal to or less than the first projected area. The upper face provides a seeding pattern having one or two degrees of freedom in a growing medium disposed in the top cavity. Each mid cavity has an upper face defining a third projected area that is entirely contained within the second projected area. The mid cavities are configured to contribute to buoyancy of the floating horticultural raft, allow germinants in the growing medium to communicate via capillary action with a nutrient solution when the raft is floating in the nutrient solution, and mitigate hyperhydration and asphyxiation at respective root-stem junctions of the germinants.

Abstract: A horticultural raft includes a raft body, at least one top cavity, and a group of mid cavities. The top cavity includes an upper face defining a first projected area and a lower face defining a second projected area substantially equal to or less than the first projected area. The upper face provides a seeding pattern having one or two degrees of freedom in a growing medium disposed in the top cavity. Each mid cavity has an upper face defining a third projected area that is entirely contained within the second projected area. The mid cavities are configured to contribute to buoyancy of the floating horticultural raft, allow germinants in the growing medium to communicate via capillary action with a nutrient solution when the raft is floating in the nutrient solution, and mitigate hyperhydration and asphyxiation at respective root-stem junctions of the germinants.

Abstract: A vertically-stacked growing system includes vertical beams and horizontal shelves respectively arranged on different vertical levels, Each horizontal shelf has a length and a width, and includes horizontal structural supports coupled to at least some of the vertical beams, decking coupled to the horizontal structural supports, and multiple walls to form a shallow pond when the horizontal shelf contains a plant nutrient water culture, thereby constituting a growing layer of the growing system. The walls include two side walls along the length and two end walls along the width. Each horizontal shelf further includes a loading and/or unloading apparatus to facilitate loading and/or unloading of a plurality of rafts into and/or out of the shallow pond, via the two end walls, wherein respective rafts of the plurality of rafts include a plurality of germinated plants.

Abstract: The present disclosure relates to a system for obtaining a therapeutic solution for treatment of a disease or a disorder. The present disclosure also relates to a method of drug discovery and designing therapeutic solutions for various medical conditions, through the said system, comprising database, digital drug library and a processor.

Abstract: A visualization method for the computation and display of seismic attributes from time-frequency spectral analysis enables high resolution investigation of 3D seismic data for the exploration of oil and gas. First, high frequency resolution time derivative or space derivative of the amplitude and phase spectra of time-windowed signals are computed. Second, the derivatives are transformed into seismic attributes that are suitable for seismic data processing or interpretation. Applications for the method are illustrated with graphical screen 3D volume displays of dip and azimuth, curvature and faults. Aside from providing high resolution these displays may improve the productivity of a seismic interpreter or data processor.

Abstract: A method and visualization apparatus for spectral analysis of time-and-space varying signals enables high resolution investigation of 3D seismic data for the exploration of oil and gas. The method extrapolates multi-resolution short windows into an average long window then computes its FFT. Extrapolation uses the continuity relationship between data inside and outside of short windows. Applications of the method are illustrated with graphical screen 3D volume displays of amplitude spectra, dip and azimuth, curvature and faults (figure below). Aside from high resolution these displays improve the productivity of a seismic interpreter.

Abstract: A dialysis device having a dialysis tube with a closed end and an open end, the open end is provided with a dialysis reservoir having a dialysis membrane.

Abstract: A method and visualization apparatus for spectral analysis of time-and-space varying signals enables high resolution investigation of 3D seismic data for the exploration of oil and gas. The method extrapolates multi-resolution short windows into an average long window then computes its FFT. Extrapolation uses the continuity relationship between data inside and outside of short windows. Applications of the method are illustrated with graphical screen 3D volume displays of amplitude spectra, dip and azimuth, curvature and faults (figure below). Aside from high resolution these displays improve the productivity of a seismic interpreter.

Abstract: A method of protein precipitation, concentration and removal of non-protein agents from the protein solution wherein the protein solution is treated with a protein-precipitation agent containing an acidic agent, a salt and a precipitate forming agent. After precipitation, the protein precipitate is washed with a water miscible organic solvent agent to remove non-protein agents present in the protein precipitate.

Abstract: A device for application of multiple liquid samples on membrane by capillary action and creation of sample arrays.

Abstract: A method of protein precipitation, concentration and removal of non-protein agents from the protein solution wherein the protein solution is treated with a protein-precipitation agent containing an acidic agent, a salt and a precipitate forming agent. After precipitation, the protein precipitate is washed with a water miscible organic solvent agent to remove non-protein agents present in the protein precipitate.

Abstract: A method of protein precipitation, concentration and removal of non-protein agents from the protein solution wherein the protein solution is treated with a protein-precipitation agent containing an acidic agent, a salt and a precipitate forming agent. After precipitation, the protein precipitate is washed with a water miscible organic solvent agent to remove non-protein agents present in the protein precipitate.

Abstract: A protein solubilization reagent made in two parts, of which one part is a dry urea-agent and the second part is a diluent for re-hydration of the dry urea-agent. The urea-agent comprises of urea and one or more agents selected from a group consisting of dry thiourea, detergents, sufobetaines, sulfonates, buffer agents, and dyes. The diluent contain pure water and other agents.

Abstract: A device for application of multiple liquid samples on membrane by capillary action and creation of sample arrays.