Abstract: Cosmetic compositions useful intended for use in cosmetics and personal care formulations are disclosed. The cosmetic compositions include a micronized, substantially uniform powder mixture of a ferment containing a polyhydroxyalkanoate such as polyhydroxybutyrate and an amino acid derivative such as the lysine derivative N6-lauroyl-L-lysine. The cosmetic powder compositions can be intermediates that enhance the textural profile of cosmetics providing sensorial improvement, and/or soft-focus effects, line blurring effects by filling unevenness in the skin, making it appear smoother with less skin imperfections and wrinkles. The powder-based compositions can serve as detackifiers and/or viscosity modifiers due to its ability to absorb oil. The powder provides formulation options for cosmetics and personal care formulas prepared from biobased and biodegradable materials. Methods of preparing the powder compositions, as well as cosmetics containing the composition are also disclosed.