Abstract: Antimicrobial cationic polymers having one or two cationic polycarbonate chains were prepared by organocatalyzed ring opening polymerization. One antimicrobial cationic polymer has a polymer chain consisting essentially of cationic carbonate repeat units linked to one or two end groups. The end groups can comprise a covalently bound form of biologically active compound such as cholesterol. Other antimicrobial cationic polymers have a random copolycarbonate chain comprising a minor mole fraction of hydrophobic repeat units bearing a covalently bound form of a vitamin E and/or vitamin D2. The cationic polymers exhibit high activity and selectivity against Gram-negative and Gram-positive microbes and fungi.

Abstract: Described herein are polymers comprising a polyester and at least one polyhedral oligomeric silsesquioxane, wherein the polyester is capable of forming a stereocomplex with a polymer comprising a complimentary polyester and composites thereof.

Abstract: We disclose a method comprising: (a) providing an embryonic stem (ES) cell; and (b) establishing a progenitor cell line from the embryonic stem cell; in which the progenitor cell line is selected based on its ability to self-renew. Preferably, the method selects against somatic cells based on their inability to self-renew. Preferably, the progenitor cell line is derived or established in the absence of co-culture, preferably in the absence of feeder cells, which preferably selects against embryonic stem cells. Optionally, the method comprises (d) deriving a differentiated cell from the progenitor cell line.

Abstract: A data storage device is provided. The data storage device includes a data storage medium having a plurality of data blocks, a cache having a plurality of cache blocks, wherein each cache block is identified by a cache block address, a cache control memory including a memory element for each data block configured to store the cache block address of the cache block in which data of the data block is written.

Abstract: According to embodiments of the present invention, a probe device is provided. The probe device includes a flexible probe that is implantable into a biological tissue, a rigid carrier, and a biodegradable material received in a recess defined between the flexible probe and the rigid carrier, the biodegradable material bonding the flexible probe and the rigid carrier to each other, wherein the biodegradable material is dissolvable in the biological tissue such that the flexible probe and the rigid carrier are separable and the rigid carrier is removable from the biological tissue, and wherein the biodegradable material is capable of drug delivery upon dissolution. According to further embodiments of the present invention, a method of fabricating a probe device is also provided.

Abstract: A laminate and process of making the laminate is disclosed comprising: a surgical mesh having first and second surfaces; and an adhesive structure having adhesive and non-adhesive surfaces, wherein the non-adhesive surface of the adhesive structure is laminated to at least one of said first and second surfaces of said surgical mesh, and the adhesive surface of said adhesive structure has protrusions extending therefrom comprising a resin having a Young's modulus of greater than 17 MPa, which protrusions are of sufficiently low diameter to promote adhesion by increasing physical attractive forces between the adhesive structure and a target surface, as measured by shear adhesion.

Abstract: A radiation sensor is provided. The radiation sensor includes a substrate; a diaphragm positioned over the substrate; an absorbing layer which is configured to absorb infrared radiation; a supporting element arranged between the absorbing layer and the diaphragm such that a spacing gap is formed between the absorbing layer and the diaphragm; wherein the size of the spacing gap is in a range of about 3.6 micrometer to about 100 micrometer.

Abstract: According to embodiments of the present invention, a resistive memory arrangement is provided. The resistive memory arrangement includes a nanowire, and a resistive memory cell including a resistive layer including a resistive changing material, wherein at least a section of the resistive layer is arranged covering at least a portion of a surface of the nanowire, and a conductive layer arranged on at least a part of the resistive layer. According to further embodiments of the present invention, a method of forming a resistive memory arrangement is also provided.

Abstract: There is provided a method for promoting stem cell chondrogenesis, comprising the step of culturing a population of stem cells on a plurality of imprints disposed on a substrate, the imprints being configured to selectively promote chondrogenesis of the stem cells.

Abstract: According to embodiments of the present invention, a semiconductor photomultiplier device is provided. The semiconductor photomultiplier device includes a substrate having a front side and a back side, a common electrode of a first conductivity type adjacent to the back side, and a cell including an active region of a second conductivity type adjacent to the front side, and a contact region of the second conductivity type adjacent to the front side, the contact region being spaced apart from the active region by a separation region.

Abstract: The invention relates to modulation of fungal morphology between yeast-to-hyphal growth transition by controlling muramyl-L-alanine concentration and uses thereof.

Abstract: The invention relates to modulation of fungal morphology between yeast-to-hyphal growth transition by controlling muramyl-L-alanine concentration and uses thereof.

Abstract: According to embodiments of the present invention, a piezoelectric actuator is provided. The piezoelectric actuator includes a shear mode piezoelectric material including a first arm and a second arm intersecting each other, the shear mode piezoelectric material having a polarization direction oriented at least substantially along a length of the first arm, wherein the shear mode piezoelectric material has a first surface and a second surface opposite to the first surface, the first surface and the second surface being adapted to undergo a shear displacement relative to each other along an axis at least substantially parallel to the polarization direction in response to an electric field applied between the first surface and the second surface in a direction at least substantially perpendicular to the polarization direction.

Abstract: An implant having an adhesive structure comprising a planar surface having two sides and rectangular cuboid-based protrusions having pyramidal tips extending from at least one of said sides, optionally having a porous basic supporting structure, and methods of making and using such implants.

Abstract: Various embodiments provide a recording medium. The recording medium may include: a dedicated servo layer for providing servo information, wherein the dedicated servo layer comprises a plurality of tracks, wherein a first track comprises a first servo signal of a first frequency, wherein a second track comprises a second servo signal of a second frequency, and wherein the first servo signal and the second servo signal comprise a common single tone signal.

Abstract: The present invention relates to a polymer functionalized with a dye, a nanoparticle comprising the dye-functionalized polymer on its surface, as well as to methods of preparing the same. In particular, it relates to a bimodal imaging agent, comprising said nanoparticles functionalized with a polymer bearing a dye with luminescence properties, and fabrication methods of the same.

Abstract: According to embodiments of the present invention, a method for providing a synchronization signal for at least one of a read operation or a write operation carried out by means of a head in a data storage device is provided. The method includes obtaining a readback servo signal from a storage medium of the data storage device by means of the head, the readback servo signal having at least one frequency associated with a servo track of the storage medium, frequency mixing the readback servo signal with a local signal having a local frequency to provide a frequency mixed signal, and filtering the frequency mixed signal to provide the synchronization signal for at least one of the read operation or the write operation. According to further embodiments of the present invention, a data storage device is also provided.

Abstract: A magnetoresistive device including a fixed magnetic layer structure, a first free magnetic layer structure, and a second free magnetic layer structure, wherein the fixed magnetic layer structure is arranged in between the first free magnetic layer structure and the second free magnetic layer structure, wherein the magnetization orientation of the first free magnetic layer structure is variable in response to a first electrical signal of a first polarity and the magnetization orientation of the second free magnetic layer structure is at least substantially non-variable in response to the first electrical signal, and wherein the magnetization orientation of the second free magnetic layer structure is variable in response to a second electrical signal of a second polarity and the magnetization orientation of the first free magnetic layer structure is at least substantially non-variable in response to the second electrical signal, wherein the second polarity is opposite to the first polarity.

Abstract: Various embodiments provide a recording medium. The recording medium may include a dedicated servo layer for providing servo information. The dedicated servo layer may include a plurality of tracks. A first track may include a first servo signal. A second track may include a second servo signal. The first servo signal and the second servo signal may include a plurality of common transitions. The transitions may be provided at a pre-determined frequency.

Abstract: According to embodiments of the present invention, a data storage device is provided. The data storage device includes a recording channel configured to carry a signal; a detector configured to detect the signal from the recording channel; and a noise prediction circuit configured to predict noise affecting the recording channel and the detected signal based on a noisy channel model. According to further embodiments of the present invention, a method of processing a signal in a data storage device is also provided.