Patents by Inventor Agnès Bénardeau

Agnès Bénardeau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS TO DETERMINE WHETHER A SUBJECT IS SUITABLE OF BEING TREATED WITH AN AGONIST OF SOLUBLE GYANYLYL CYCLASE (SGC)
    Publication number: 20220128561
    Abstract: The present invention provides a method for determining whether a human or animal subject suffers from oxidative stress, is suitable of being treated with an antioxidant and/or free radical scavenger, and/or is suitable of being treated with an agonist of soluble Guanylyl Cyclase (sGC), in particular with an activator of sGC, said method comprising the steps of providing a tissue or liquid sample from said subject, and determining whether or not said sample is characterized by the presence, upregulation or overexpression of sGC comprising a heme free ?1 subunit.
    Type: Application
    Filed: January 16, 2020
    Publication date: April 28, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventors: Rene Hoet, Peter Sandner, Jan Robert Krähling, Agnes Benardeau, Ana Lúcia Freitas de Mesquita Barbas, Ligia Nobre, Hugo Soares, Gabriela Silva
  • USE OF AMINODIHYDROTHIAZINES FOR THE TREATMENT OR PREVENTION OF DIABETES
    Publication number: 20140221360
    Abstract: This invention relates to compounds of formula I, wherein R1 to R3 are as defined herein, as well as pharmaceutically acceptable salts thereof, pharmaceutical compositions containing such compounds and methods for using such compounds for the treatment or prevention of diabetes, particularly type 2 diabetes.
    Type: Application
    Filed: April 4, 2014
    Publication date: August 7, 2014
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jeremy Beauchamp, Agnes Benardeau, Hans Hilpert, Cristiano Migliorini, William Riboulet, Haiyan Wang
  • Pyrazinecarboxamide derivatives as HDL-cholesterol raising agents
    Patent number: 8188093
    Abstract: The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula wherein A, G, R1 to R8 and R17 are as defined in the description.
    Type: Grant
    Filed: June 29, 2010
    Date of Patent: May 29, 2012
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Mirjana Andjelkovic, Agnes Benardeau, Evelyne Chaput, Paul Hebeisen, Matthias Nettekoven, Ulrike Obst Sander, Constantinos G. Panousis, Stephan Roever
  • Diabetogenic rat model
    Patent number: 8187572
    Abstract: The present invention provides a method of producing diabetic rats, and a method for identifying compounds that reverse diabetes in said rats.
    Type: Grant
    Filed: July 5, 2006
    Date of Patent: May 29, 2012
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Agnes Benardeau, Emmanuelle Hainaut, Philippe Verry
  • USE OF AMINODIHYDROTHIAZINES FOR THE TREATMENT OR PREVENTION OF DIABETES
    Publication number: 20110065695
    Abstract: This invention relates to compounds of formula I, wherein R1 to R3 are as defined herein, as well as pharmaceutically acceptable salts thereof, pharmaceutical compositions containing such compounds and methods for using such compounds for the treatment or prevention of diabetes, particularly type 2 diabetes.
    Type: Application
    Filed: September 2, 2010
    Publication date: March 17, 2011
    Inventors: Jeremy Beauchamp, Agnès Bénardeau, Hans Hilpert, Cristiano Mighliorini, William Riboulet, Haiyan Wang
  • COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF GLUCOCORTICOID RECEPTOR (GCR) GENES
    Publication number: 20110020300
    Abstract: This invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a GCR gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of a GCR gene using said pharmaceutical composition; and methods for inhibiting the expression of GCR in a cell.
    Type: Application
    Filed: May 14, 2010
    Publication date: January 27, 2011
    Applicant: GENENTECH, INC.
    Inventors: JACQUES BAILLY, AGNÈS BÉNARDEAU, BIRGIT BRAMLAGE, RAINER CONSTIEN, ANDREA FORST, MARKUS HOSSBACH, BRIGITTE SCHOTT
  • 3-Pyridinecarboxamide Derivatives as HDL-Cholesterol Raising Agents
    Publication number: 20100267745
    Abstract: The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula wherein A, G, R1 to R8 and R17 are as defined in the description.
    Type: Application
    Filed: June 29, 2010
    Publication date: October 21, 2010
    Inventors: Mirjana Andjelkovic, Agnès Bénardeau, Evelyne Chaput, Paul Hebeisen, Matthias Nettekoven, Ulrike Obst Sander, Constantinos G. Panousis, Stephan Roever
  • 3-pyridinecarboxamide derivatives as HDL-cholesterol raising agents
    Patent number: 7812028
    Abstract: The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula wherein A, G, R1 to R8 and R17 are as defined in the description.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: October 12, 2010
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Mirjana Andjelkovic, Agnes Benardeau, Evelyne Chaput, Paul Hebeisen, Matthias Nettekoven, Ulrike Obst Sander, Constantinos G. Panousis, Stephan Roever
  • 3-PYRIDINECARBOXAMIDE DERIVATIVES AS HDL-CHOLESTEROL RAISING AGENTS
    Publication number: 20090143409
    Abstract: The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula wherein A, G, R1 to R8 and R17 are as defined in the description.
    Type: Application
    Filed: February 6, 2009
    Publication date: June 4, 2009
    Inventors: Mirjana Andjelkovic, Agnes Benardeau, Evelyne Chaput, Paul Hebeisen, Matthias Nettekoven, Ulrike Obst Sander, Constantinos G. Panousis, Stephan Roever
  • 3-Pyridinecarboxamide derivatives as HDL-cholesterol raising agents
    Publication number: 20080085906
    Abstract: The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula wherein A, G, R1 to R8 and R17 are as defined in the description.
    Type: Application
    Filed: September 27, 2007
    Publication date: April 10, 2008
    Inventors: Mirjana Andjelkovic, Agnes Benardeau, Evelyne Chaput, Paul Hebeisen, Matthias Nettekoven, Ulrike Sander, Constantinos Panousis, Stephan Roever
  • Diabetogenic rat model
    Publication number: 20070009439
    Abstract: The present invention provides a method of producing diabetic rats, and a method for identifying compounds that reverse diabetes in said rats.
    Type: Application
    Filed: July 5, 2006
    Publication date: January 11, 2007
    Inventors: Agnes Benardeau, Emmanuelle Hainaut, Philippe Verry