Patents by Inventor Agnes Csiszar

Agnes Csiszar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecule mixture comprising an amphipathic molecule type A, which has a positive total charge in the hydrophilic range, and an amphipathic molecule type B and A polyphenol C, method for producing said molecule mixture and use thereof
    Patent number: 9610254
    Abstract: A molecule mixture comprising an amphipathic molecule of type A, which has an overall positive charge in the hydrophilic region, an amphipathic molecule of type B and a polyphenol C, the method for producing the molecule mixture, and the use thereof. The molecules of types A and B are present at a molecular ratio of A:B of 1(±0.2):1(±0.2) mol/mol. A method for producing the mixture and the use is also disclosed.
    Type: Grant
    Filed: October 1, 2012
    Date of Patent: April 4, 2017
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Agnes Csiszar, Christian Kleusch, Bernd Hoffmann, Rudolf Merkel
  • METHOD FOR PRODUCING A FUSION MIXTURE FOR TRANSFER OF A CHARGED MOLECULE INTO AND/OR THROUGH A LIPID MEMBRANE
    Publication number: 20170009255
    Abstract: A method for producing a fusion mixture for a transfer of a charged molecule into and/or through a lipid membrane is disclosed. In an embodiment, the method comprises: providing an initial mixture comprising a positively charged amphipathic molecule A, an aromatic molecule B with hydrophobic range and a neutral, amphipathic molecule C, whereby the molecule types are at hand in a ratio A:B:C of 1-2:0.02-1:0-1 mol/mol; generating a fusogenic liposome by absorption of the initial mixture in a watery solvent; providing a charged molecule; forming a complex from the charged molecule and a neutralizing agent; and incubating the complex with the fusogenic liposome so that a fusion mixture is obtained.
    Type: Application
    Filed: July 8, 2016
    Publication date: January 12, 2017
    Inventors: Bernd Hoffmann, Agnes Csiszar, Nils Hersch, Rudolf Merkel, Marco Hoffmann, Roman ZANTL
  • FUSION MIXTURE
    Publication number: 20160060602
    Abstract: The invention relates to a fusion mixture for the lipid-containing membrane modification of an arbitrary target membrane, a cell membrane, a constituent of a cell membrane or a cell membrane separated from remaining cell constituents, in vivo or in vitro, comprising a positively charged amphipathic molecule A and an aromatic molecule B, wherein the molecule of type A and the molecule of type B are present at a ratio A:B of 1:0:02 to 1:2 mol/mol.
    Type: Application
    Filed: March 21, 2014
    Publication date: March 3, 2016
    Inventors: Bernd HOFFMANN, Agnes CSISZAR, Nils HERSCH, Rudolf MERKEL
  • MOLECULE MIXTURE COMPRISING AN AMPHIPATHIC MOLECULE TYPE A, WHICH HAS A POSITIVE TOTAL CHARGE IN THE HYDROPHILIC RANGE, AND AN AMPHIPATHIC MOLECULE TYPE B AND A POLYPHENOL C, METHOD FOR PRODUCING SAID MOLECULE MIXTURE AND USE THEREOF
    Publication number: 20150037398
    Abstract: A molecule mixture comprising an amphipathic molecule of type A, which has an overall positive charge in the hydrophilic region, an amphipathic molecule of type B and a polyphenol C, the method for producing the molecule mixture, and the use thereof. The molecules of types A and B are present at a molecular ratio of A:B of 1(±0.2):1(±0.2) mol/mol. A method for producing the mixture and the use is also disclosed.
    Type: Application
    Filed: October 1, 2012
    Publication date: February 5, 2015
    Applicant: FORSCHUNGSZENTRUM JÜLICH GMBH
    Inventors: Agnes Csiszar, Christian Kleusch, Bernd Hoffmann, Rudolf Merkel
  • MIXTURE OF AMPHIPATHIC MOLECULES AND METHOD FOR MODIFYING CELL MEMBRANES BY MEANS OF FUSION
    Publication number: 20120100077
    Abstract: Disclosed is a mixture of amphipathic molecules and a method for modifying cells in vivo by way of membrane fusion with these molecules.
    Type: Application
    Filed: July 8, 2010
    Publication date: April 26, 2012
    Applicant: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventors: Bernd Hoffmann, Agnes Csiszar, Nils Hersch, Rudolf Merkel